Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in S...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Meazza, Raffaella [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2014 |
|---|
| Schlagwörter: |
|---|
| Umfang: |
12497 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward - Papakitsou, I. ELSEVIER, 2022, official publication of the American Academy of Allergy, Asthma and Immunology, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:134 ; year:2014 ; number:6 ; pages:1381-13877 ; extent:12497 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.jaci.2014.04.043 |
|---|
| Katalog-ID: |
ELV011988541 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV011988541 | ||
| 003 | DE-627 | ||
| 005 | 20230623093732.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180602s2014 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.jaci.2014.04.043 |2 doi | |
| 028 | 5 | 2 | |a GBVA2014001000008.pica |
| 035 | |a (DE-627)ELV011988541 | ||
| 035 | |a (ELSEVIER)S0091-6749(14)00771-4 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | |a 610 | |
| 082 | 0 | 4 | |a 610 |q DE-600 |
| 082 | 0 | 4 | |a 610 |q VZ |
| 084 | |a 44.85 |2 bkl | ||
| 100 | 1 | |a Meazza, Raffaella |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis |
| 264 | 1 | |c 2014 | |
| 300 | |a 12497 | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells. | ||
| 650 | 7 | |a NK cells |2 Elsevier | |
| 650 | 7 | |a SAP expression |2 Elsevier | |
| 650 | 7 | |a 2B4 function |2 Elsevier | |
| 650 | 7 | |a HLH |2 Elsevier | |
| 650 | 7 | |a XLP1 |2 Elsevier | |
| 700 | 1 | |a Tuberosa, Claudia |4 oth | |
| 700 | 1 | |a Cetica, Valentina |4 oth | |
| 700 | 1 | |a Falco, Michela |4 oth | |
| 700 | 1 | |a Parolini, Silvia |4 oth | |
| 700 | 1 | |a Grieve, Sam |4 oth | |
| 700 | 1 | |a Griffiths, Gillian M. |4 oth | |
| 700 | 1 | |a Sieni, Elena |4 oth | |
| 700 | 1 | |a Marcenaro, Stefania |4 oth | |
| 700 | 1 | |a Micalizzi, Concetta |4 oth | |
| 700 | 1 | |a Montin, Davide |4 oth | |
| 700 | 1 | |a Fagioli, Franca |4 oth | |
| 700 | 1 | |a Moretta, Alessandro |4 oth | |
| 700 | 1 | |a Mingari, Maria C. |4 oth | |
| 700 | 1 | |a Moretta, Lorenzo |4 oth | |
| 700 | 1 | |a Notarangelo, Luigi D. |4 oth | |
| 700 | 1 | |a Bottino, Cristina |4 oth | |
| 700 | 1 | |a Aricò, Maurizio |4 oth | |
| 700 | 1 | |a Pende, Daniela |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier |a Papakitsou, I. ELSEVIER |t Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward |d 2022 |d official publication of the American Academy of Allergy, Asthma and Immunology |g Amsterdam [u.a.] |w (DE-627)ELV000021164 |
| 773 | 1 | 8 | |g volume:134 |g year:2014 |g number:6 |g pages:1381-13877 |g extent:12497 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.jaci.2014.04.043 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a SSG-OLC-PHA | ||
| 936 | b | k | |a 44.85 |j Kardiologie |j Angiologie |q VZ |
| 951 | |a AR | ||
| 952 | |d 134 |j 2014 |e 6 |h 1381-13877 |g 12497 | ||
| 953 | |2 045F |a 610 | ||
| author_variant |
r m rm |
|---|---|
| matchkey_str |
meazzaraffaellatuberosaclaudiaceticavale:2014----:igoigl1nainsiheohgctcy |
| hierarchy_sort_str |
2014 |
| bklnumber |
44.85 |
| publishDate |
2014 |
| allfields |
10.1016/j.jaci.2014.04.043 doi GBVA2014001000008.pica (DE-627)ELV011988541 (ELSEVIER)S0091-6749(14)00771-4 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Meazza, Raffaella verfasserin aut Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis 2014 12497 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells. NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 Elsevier Tuberosa, Claudia oth Cetica, Valentina oth Falco, Michela oth Parolini, Silvia oth Grieve, Sam oth Griffiths, Gillian M. oth Sieni, Elena oth Marcenaro, Stefania oth Micalizzi, Concetta oth Montin, Davide oth Fagioli, Franca oth Moretta, Alessandro oth Mingari, Maria C. oth Moretta, Lorenzo oth Notarangelo, Luigi D. oth Bottino, Cristina oth Aricò, Maurizio oth Pende, Daniela oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:134 year:2014 number:6 pages:1381-13877 extent:12497 https://doi.org/10.1016/j.jaci.2014.04.043 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 134 2014 6 1381-13877 12497 045F 610 |
| spelling |
10.1016/j.jaci.2014.04.043 doi GBVA2014001000008.pica (DE-627)ELV011988541 (ELSEVIER)S0091-6749(14)00771-4 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Meazza, Raffaella verfasserin aut Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis 2014 12497 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells. NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 Elsevier Tuberosa, Claudia oth Cetica, Valentina oth Falco, Michela oth Parolini, Silvia oth Grieve, Sam oth Griffiths, Gillian M. oth Sieni, Elena oth Marcenaro, Stefania oth Micalizzi, Concetta oth Montin, Davide oth Fagioli, Franca oth Moretta, Alessandro oth Mingari, Maria C. oth Moretta, Lorenzo oth Notarangelo, Luigi D. oth Bottino, Cristina oth Aricò, Maurizio oth Pende, Daniela oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:134 year:2014 number:6 pages:1381-13877 extent:12497 https://doi.org/10.1016/j.jaci.2014.04.043 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 134 2014 6 1381-13877 12497 045F 610 |
| allfields_unstemmed |
10.1016/j.jaci.2014.04.043 doi GBVA2014001000008.pica (DE-627)ELV011988541 (ELSEVIER)S0091-6749(14)00771-4 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Meazza, Raffaella verfasserin aut Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis 2014 12497 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells. NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 Elsevier Tuberosa, Claudia oth Cetica, Valentina oth Falco, Michela oth Parolini, Silvia oth Grieve, Sam oth Griffiths, Gillian M. oth Sieni, Elena oth Marcenaro, Stefania oth Micalizzi, Concetta oth Montin, Davide oth Fagioli, Franca oth Moretta, Alessandro oth Mingari, Maria C. oth Moretta, Lorenzo oth Notarangelo, Luigi D. oth Bottino, Cristina oth Aricò, Maurizio oth Pende, Daniela oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:134 year:2014 number:6 pages:1381-13877 extent:12497 https://doi.org/10.1016/j.jaci.2014.04.043 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 134 2014 6 1381-13877 12497 045F 610 |
| allfieldsGer |
10.1016/j.jaci.2014.04.043 doi GBVA2014001000008.pica (DE-627)ELV011988541 (ELSEVIER)S0091-6749(14)00771-4 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Meazza, Raffaella verfasserin aut Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis 2014 12497 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells. NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 Elsevier Tuberosa, Claudia oth Cetica, Valentina oth Falco, Michela oth Parolini, Silvia oth Grieve, Sam oth Griffiths, Gillian M. oth Sieni, Elena oth Marcenaro, Stefania oth Micalizzi, Concetta oth Montin, Davide oth Fagioli, Franca oth Moretta, Alessandro oth Mingari, Maria C. oth Moretta, Lorenzo oth Notarangelo, Luigi D. oth Bottino, Cristina oth Aricò, Maurizio oth Pende, Daniela oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:134 year:2014 number:6 pages:1381-13877 extent:12497 https://doi.org/10.1016/j.jaci.2014.04.043 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 134 2014 6 1381-13877 12497 045F 610 |
| allfieldsSound |
10.1016/j.jaci.2014.04.043 doi GBVA2014001000008.pica (DE-627)ELV011988541 (ELSEVIER)S0091-6749(14)00771-4 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Meazza, Raffaella verfasserin aut Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis 2014 12497 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells. NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 Elsevier Tuberosa, Claudia oth Cetica, Valentina oth Falco, Michela oth Parolini, Silvia oth Grieve, Sam oth Griffiths, Gillian M. oth Sieni, Elena oth Marcenaro, Stefania oth Micalizzi, Concetta oth Montin, Davide oth Fagioli, Franca oth Moretta, Alessandro oth Mingari, Maria C. oth Moretta, Lorenzo oth Notarangelo, Luigi D. oth Bottino, Cristina oth Aricò, Maurizio oth Pende, Daniela oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:134 year:2014 number:6 pages:1381-13877 extent:12497 https://doi.org/10.1016/j.jaci.2014.04.043 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 134 2014 6 1381-13877 12497 045F 610 |
| language |
English |
| source |
Enthalten in Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward Amsterdam [u.a.] volume:134 year:2014 number:6 pages:1381-13877 extent:12497 |
| sourceStr |
Enthalten in Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward Amsterdam [u.a.] volume:134 year:2014 number:6 pages:1381-13877 extent:12497 |
| format_phy_str_mv |
Article |
| bklname |
Kardiologie Angiologie |
| institution |
findex.gbv.de |
| topic_facet |
NK cells SAP expression 2B4 function HLH XLP1 |
| dewey-raw |
610 |
| isfreeaccess_bool |
false |
| container_title |
Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward |
| authorswithroles_txt_mv |
Meazza, Raffaella @@aut@@ Tuberosa, Claudia @@oth@@ Cetica, Valentina @@oth@@ Falco, Michela @@oth@@ Parolini, Silvia @@oth@@ Grieve, Sam @@oth@@ Griffiths, Gillian M. @@oth@@ Sieni, Elena @@oth@@ Marcenaro, Stefania @@oth@@ Micalizzi, Concetta @@oth@@ Montin, Davide @@oth@@ Fagioli, Franca @@oth@@ Moretta, Alessandro @@oth@@ Mingari, Maria C. @@oth@@ Moretta, Lorenzo @@oth@@ Notarangelo, Luigi D. @@oth@@ Bottino, Cristina @@oth@@ Aricò, Maurizio @@oth@@ Pende, Daniela @@oth@@ |
| publishDateDaySort_date |
2014-01-01T00:00:00Z |
| hierarchy_top_id |
ELV000021164 |
| dewey-sort |
3610 |
| id |
ELV011988541 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV011988541</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230623093732.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180602s2014 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.jaci.2014.04.043</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBVA2014001000008.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV011988541</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0091-6749(14)00771-4</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.85</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Meazza, Raffaella</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">12497</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">NK cells</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">SAP expression</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">2B4 function</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">HLH</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">XLP1</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tuberosa, Claudia</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cetica, Valentina</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Falco, Michela</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Parolini, Silvia</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Grieve, Sam</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Griffiths, Gillian M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sieni, Elena</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Marcenaro, Stefania</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Micalizzi, Concetta</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Montin, Davide</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fagioli, Franca</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Moretta, Alessandro</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mingari, Maria C.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Moretta, Lorenzo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Notarangelo, Luigi D.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bottino, Cristina</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Aricò, Maurizio</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pende, Daniela</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Papakitsou, I. ELSEVIER</subfield><subfield code="t">Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward</subfield><subfield code="d">2022</subfield><subfield code="d">official publication of the American Academy of Allergy, Asthma and Immunology</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV000021164</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:134</subfield><subfield code="g">year:2014</subfield><subfield code="g">number:6</subfield><subfield code="g">pages:1381-13877</subfield><subfield code="g">extent:12497</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.jaci.2014.04.043</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.85</subfield><subfield code="j">Kardiologie</subfield><subfield code="j">Angiologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">134</subfield><subfield code="j">2014</subfield><subfield code="e">6</subfield><subfield code="h">1381-13877</subfield><subfield code="g">12497</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">610</subfield></datafield></record></collection>
|
| author |
Meazza, Raffaella |
| spellingShingle |
Meazza, Raffaella ddc 610 bkl 44.85 Elsevier NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis |
| authorStr |
Meazza, Raffaella |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV000021164 |
| format |
electronic Article |
| dewey-ones |
610 - Medicine & health |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
610 610 DE-600 610 VZ 44.85 bkl Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 Elsevier |
| topic |
ddc 610 bkl 44.85 Elsevier NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 |
| topic_unstemmed |
ddc 610 bkl 44.85 Elsevier NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 |
| topic_browse |
ddc 610 bkl 44.85 Elsevier NK cells Elsevier SAP expression Elsevier 2B4 function Elsevier HLH Elsevier XLP1 |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
c t ct v c vc m f mf s p sp s g sg g m g gm gmg e s es s m sm c m cm d m dm f f ff a m am m c m mc mcm l m lm l d n ld ldn c b cb m a ma d p dp |
| hierarchy_parent_title |
Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward |
| hierarchy_parent_id |
ELV000021164 |
| dewey-tens |
610 - Medicine & health |
| hierarchy_top_title |
Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV000021164 |
| title |
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis |
| ctrlnum |
(DE-627)ELV011988541 (ELSEVIER)S0091-6749(14)00771-4 |
| title_full |
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis |
| author_sort |
Meazza, Raffaella |
| journal |
Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward |
| journalStr |
Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
600 - Technology |
| recordtype |
marc |
| publishDateSort |
2014 |
| contenttype_str_mv |
zzz |
| container_start_page |
1381 |
| author_browse |
Meazza, Raffaella |
| container_volume |
134 |
| physical |
12497 |
| class |
610 610 DE-600 610 VZ 44.85 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Meazza, Raffaella |
| doi_str_mv |
10.1016/j.jaci.2014.04.043 |
| dewey-full |
610 |
| title_sort |
diagnosing xlp1 in patients with hemophagocytic lymphohistiocytosis |
| title_auth |
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis |
| abstract |
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells. |
| abstractGer |
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells. |
| abstract_unstemmed |
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
| container_issue |
6 |
| title_short |
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis |
| url |
https://doi.org/10.1016/j.jaci.2014.04.043 |
| remote_bool |
true |
| author2 |
Tuberosa, Claudia Cetica, Valentina Falco, Michela Parolini, Silvia Grieve, Sam Griffiths, Gillian M. Sieni, Elena Marcenaro, Stefania Micalizzi, Concetta Montin, Davide Fagioli, Franca Moretta, Alessandro Mingari, Maria C. Moretta, Lorenzo Notarangelo, Luigi D. Bottino, Cristina Aricò, Maurizio Pende, Daniela |
| author2Str |
Tuberosa, Claudia Cetica, Valentina Falco, Michela Parolini, Silvia Grieve, Sam Griffiths, Gillian M. Sieni, Elena Marcenaro, Stefania Micalizzi, Concetta Montin, Davide Fagioli, Franca Moretta, Alessandro Mingari, Maria C. Moretta, Lorenzo Notarangelo, Luigi D. Bottino, Cristina Aricò, Maurizio Pende, Daniela |
| ppnlink |
ELV000021164 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth oth oth oth oth oth oth oth oth oth oth oth oth oth |
| doi_str |
10.1016/j.jaci.2014.04.043 |
| up_date |
2024-07-06T21:14:14.266Z |
| _version_ |
1803865769134522368 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV011988541</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230623093732.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">180602s2014 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.jaci.2014.04.043</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBVA2014001000008.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV011988541</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0091-6749(14)00771-4</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.85</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Meazza, Raffaella</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">12497</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, heterogeneous, hyperinflammmatory disorder. Prompt identification of inherited forms resulting from mutation in genes involved in cellular cytotoxicity can be crucial. X-linked lymphoproliferative disease 1 (XLP1), due to mutations in SH2D1A (Xq25) encoding signaling lymphocyte activation molecule–associated protein (SAP), may present with HLH. Defective SAP induces paradoxical inhibitory function of the 2B4 coreceptor and impaired natural killer (NK) (and T) cell response against EBV-infected cells.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">NK cells</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">SAP expression</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">2B4 function</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">HLH</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">XLP1</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tuberosa, Claudia</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cetica, Valentina</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Falco, Michela</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Parolini, Silvia</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Grieve, Sam</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Griffiths, Gillian M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sieni, Elena</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Marcenaro, Stefania</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Micalizzi, Concetta</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Montin, Davide</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fagioli, Franca</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Moretta, Alessandro</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mingari, Maria C.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Moretta, Lorenzo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Notarangelo, Luigi D.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bottino, Cristina</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Aricò, Maurizio</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pende, Daniela</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Papakitsou, I. ELSEVIER</subfield><subfield code="t">Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward</subfield><subfield code="d">2022</subfield><subfield code="d">official publication of the American Academy of Allergy, Asthma and Immunology</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV000021164</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:134</subfield><subfield code="g">year:2014</subfield><subfield code="g">number:6</subfield><subfield code="g">pages:1381-13877</subfield><subfield code="g">extent:12497</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.jaci.2014.04.043</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.85</subfield><subfield code="j">Kardiologie</subfield><subfield code="j">Angiologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">134</subfield><subfield code="j">2014</subfield><subfield code="e">6</subfield><subfield code="h">1381-13877</subfield><subfield code="g">12497</subfield></datafield><datafield tag="953" ind1=" " ind2=" "><subfield code="2">045F</subfield><subfield code="a">610</subfield></datafield></record></collection>
|
| score |
7.3986187 |