Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA
A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-l...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Charbonnier, Louis-Marie [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
LPS-responsive beige-like anchor |
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| Umfang: |
2063 |
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| Übergeordnetes Werk: |
Enthalten in: Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward - Papakitsou, I. ELSEVIER, 2022, official publication of the American Academy of Allergy, Asthma and Immunology, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:135 ; year:2015 ; number:1 ; pages:217-2279 ; extent:2063 |
| Links: |
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| DOI / URN: |
10.1016/j.jaci.2014.10.019 |
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| Katalog-ID: |
ELV012728594 |
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| 520 | |a A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused by mutations in IL-2 receptor α (IL2RA), signal transducer and activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT1). However, the genetic defects underlying many cases of IPEX-like disorders remain unknown. | ||
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| 650 | 7 | |a autoimmunity |2 Elsevier | |
| 650 | 7 | |a polyendocrinopathy |2 Elsevier | |
| 650 | 7 | |a enteropathy |2 Elsevier | |
| 650 | 7 | |a X-linked syndrome |2 Elsevier | |
| 650 | 7 | |a mammalian target of rapamycin complex |2 Elsevier | |
| 650 | 7 | |a forkhead box P3 |2 Elsevier | |
| 650 | 7 | |a T follicular helper cells |2 Elsevier | |
| 650 | 7 | |a immune dysregulation |2 Elsevier | |
| 650 | 7 | |a T follicular regulatory cells |2 Elsevier | |
| 700 | 1 | |a Janssen, Erin |4 oth | |
| 700 | 1 | |a Chou, Janet |4 oth | |
| 700 | 1 | |a Ohsumi, Toshiro K. |4 oth | |
| 700 | 1 | |a Keles, Sevgi |4 oth | |
| 700 | 1 | |a Hsu, Joyce T. |4 oth | |
| 700 | 1 | |a Massaad, Michel J. |4 oth | |
| 700 | 1 | |a Garcia-Lloret, Maria |4 oth | |
| 700 | 1 | |a Hanna-Wakim, Rima |4 oth | |
| 700 | 1 | |a Dbaibo, Ghassan |4 oth | |
| 700 | 1 | |a Alangari, Abdullah A. |4 oth | |
| 700 | 1 | |a Alsultan, Abdulrahman |4 oth | |
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| 700 | 1 | |a Geha, Raif S. |4 oth | |
| 700 | 1 | |a Chatila, Talal A. |4 oth | |
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10.1016/j.jaci.2014.10.019 doi GBVA2015001000029.pica (DE-627)ELV012728594 (ELSEVIER)S0091-6749(14)01514-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Charbonnier, Louis-Marie verfasserin aut Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA 2015 2063 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused by mutations in IL-2 receptor α (IL2RA), signal transducer and activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT1). However, the genetic defects underlying many cases of IPEX-like disorders remain unknown. regulatory T cells Elsevier LPS-responsive beige-like anchor Elsevier Autoantibodies Elsevier autoimmunity Elsevier polyendocrinopathy Elsevier enteropathy Elsevier X-linked syndrome Elsevier mammalian target of rapamycin complex Elsevier forkhead box P3 Elsevier T follicular helper cells Elsevier immune dysregulation Elsevier T follicular regulatory cells Elsevier Janssen, Erin oth Chou, Janet oth Ohsumi, Toshiro K. oth Keles, Sevgi oth Hsu, Joyce T. oth Massaad, Michel J. oth Garcia-Lloret, Maria oth Hanna-Wakim, Rima oth Dbaibo, Ghassan oth Alangari, Abdullah A. oth Alsultan, Abdulrahman oth Al-Zahrani, Daifulah oth Geha, Raif S. oth Chatila, Talal A. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:135 year:2015 number:1 pages:217-2279 extent:2063 https://doi.org/10.1016/j.jaci.2014.10.019 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 135 2015 1 217-2279 2063 045F 610 |
| spelling |
10.1016/j.jaci.2014.10.019 doi GBVA2015001000029.pica (DE-627)ELV012728594 (ELSEVIER)S0091-6749(14)01514-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Charbonnier, Louis-Marie verfasserin aut Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA 2015 2063 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused by mutations in IL-2 receptor α (IL2RA), signal transducer and activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT1). However, the genetic defects underlying many cases of IPEX-like disorders remain unknown. regulatory T cells Elsevier LPS-responsive beige-like anchor Elsevier Autoantibodies Elsevier autoimmunity Elsevier polyendocrinopathy Elsevier enteropathy Elsevier X-linked syndrome Elsevier mammalian target of rapamycin complex Elsevier forkhead box P3 Elsevier T follicular helper cells Elsevier immune dysregulation Elsevier T follicular regulatory cells Elsevier Janssen, Erin oth Chou, Janet oth Ohsumi, Toshiro K. oth Keles, Sevgi oth Hsu, Joyce T. oth Massaad, Michel J. oth Garcia-Lloret, Maria oth Hanna-Wakim, Rima oth Dbaibo, Ghassan oth Alangari, Abdullah A. oth Alsultan, Abdulrahman oth Al-Zahrani, Daifulah oth Geha, Raif S. oth Chatila, Talal A. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:135 year:2015 number:1 pages:217-2279 extent:2063 https://doi.org/10.1016/j.jaci.2014.10.019 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 135 2015 1 217-2279 2063 045F 610 |
| allfields_unstemmed |
10.1016/j.jaci.2014.10.019 doi GBVA2015001000029.pica (DE-627)ELV012728594 (ELSEVIER)S0091-6749(14)01514-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Charbonnier, Louis-Marie verfasserin aut Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA 2015 2063 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused by mutations in IL-2 receptor α (IL2RA), signal transducer and activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT1). However, the genetic defects underlying many cases of IPEX-like disorders remain unknown. regulatory T cells Elsevier LPS-responsive beige-like anchor Elsevier Autoantibodies Elsevier autoimmunity Elsevier polyendocrinopathy Elsevier enteropathy Elsevier X-linked syndrome Elsevier mammalian target of rapamycin complex Elsevier forkhead box P3 Elsevier T follicular helper cells Elsevier immune dysregulation Elsevier T follicular regulatory cells Elsevier Janssen, Erin oth Chou, Janet oth Ohsumi, Toshiro K. oth Keles, Sevgi oth Hsu, Joyce T. oth Massaad, Michel J. oth Garcia-Lloret, Maria oth Hanna-Wakim, Rima oth Dbaibo, Ghassan oth Alangari, Abdullah A. oth Alsultan, Abdulrahman oth Al-Zahrani, Daifulah oth Geha, Raif S. oth Chatila, Talal A. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:135 year:2015 number:1 pages:217-2279 extent:2063 https://doi.org/10.1016/j.jaci.2014.10.019 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 135 2015 1 217-2279 2063 045F 610 |
| allfieldsGer |
10.1016/j.jaci.2014.10.019 doi GBVA2015001000029.pica (DE-627)ELV012728594 (ELSEVIER)S0091-6749(14)01514-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Charbonnier, Louis-Marie verfasserin aut Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA 2015 2063 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused by mutations in IL-2 receptor α (IL2RA), signal transducer and activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT1). However, the genetic defects underlying many cases of IPEX-like disorders remain unknown. regulatory T cells Elsevier LPS-responsive beige-like anchor Elsevier Autoantibodies Elsevier autoimmunity Elsevier polyendocrinopathy Elsevier enteropathy Elsevier X-linked syndrome Elsevier mammalian target of rapamycin complex Elsevier forkhead box P3 Elsevier T follicular helper cells Elsevier immune dysregulation Elsevier T follicular regulatory cells Elsevier Janssen, Erin oth Chou, Janet oth Ohsumi, Toshiro K. oth Keles, Sevgi oth Hsu, Joyce T. oth Massaad, Michel J. oth Garcia-Lloret, Maria oth Hanna-Wakim, Rima oth Dbaibo, Ghassan oth Alangari, Abdullah A. oth Alsultan, Abdulrahman oth Al-Zahrani, Daifulah oth Geha, Raif S. oth Chatila, Talal A. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:135 year:2015 number:1 pages:217-2279 extent:2063 https://doi.org/10.1016/j.jaci.2014.10.019 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 135 2015 1 217-2279 2063 045F 610 |
| allfieldsSound |
10.1016/j.jaci.2014.10.019 doi GBVA2015001000029.pica (DE-627)ELV012728594 (ELSEVIER)S0091-6749(14)01514-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Charbonnier, Louis-Marie verfasserin aut Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA 2015 2063 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused by mutations in IL-2 receptor α (IL2RA), signal transducer and activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT1). However, the genetic defects underlying many cases of IPEX-like disorders remain unknown. regulatory T cells Elsevier LPS-responsive beige-like anchor Elsevier Autoantibodies Elsevier autoimmunity Elsevier polyendocrinopathy Elsevier enteropathy Elsevier X-linked syndrome Elsevier mammalian target of rapamycin complex Elsevier forkhead box P3 Elsevier T follicular helper cells Elsevier immune dysregulation Elsevier T follicular regulatory cells Elsevier Janssen, Erin oth Chou, Janet oth Ohsumi, Toshiro K. oth Keles, Sevgi oth Hsu, Joyce T. oth Massaad, Michel J. oth Garcia-Lloret, Maria oth Hanna-Wakim, Rima oth Dbaibo, Ghassan oth Alangari, Abdullah A. oth Alsultan, Abdulrahman oth Al-Zahrani, Daifulah oth Geha, Raif S. oth Chatila, Talal A. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:135 year:2015 number:1 pages:217-2279 extent:2063 https://doi.org/10.1016/j.jaci.2014.10.019 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 135 2015 1 217-2279 2063 045F 610 |
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Enthalten in Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward Amsterdam [u.a.] volume:135 year:2015 number:1 pages:217-2279 extent:2063 |
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Enthalten in Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward Amsterdam [u.a.] volume:135 year:2015 number:1 pages:217-2279 extent:2063 |
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regulatory T cells LPS-responsive beige-like anchor Autoantibodies autoimmunity polyendocrinopathy enteropathy X-linked syndrome mammalian target of rapamycin complex forkhead box P3 T follicular helper cells immune dysregulation T follicular regulatory cells |
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Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward |
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Charbonnier, Louis-Marie @@aut@@ Janssen, Erin @@oth@@ Chou, Janet @@oth@@ Ohsumi, Toshiro K. @@oth@@ Keles, Sevgi @@oth@@ Hsu, Joyce T. @@oth@@ Massaad, Michel J. @@oth@@ Garcia-Lloret, Maria @@oth@@ Hanna-Wakim, Rima @@oth@@ Dbaibo, Ghassan @@oth@@ Alangari, Abdullah A. @@oth@@ Alsultan, Abdulrahman @@oth@@ Al-Zahrani, Daifulah @@oth@@ Geha, Raif S. @@oth@@ Chatila, Talal A. @@oth@@ |
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Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA |
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A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused by mutations in IL-2 receptor α (IL2RA), signal transducer and activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT1). However, the genetic defects underlying many cases of IPEX-like disorders remain unknown. |
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A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused by mutations in IL-2 receptor α (IL2RA), signal transducer and activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT1). However, the genetic defects underlying many cases of IPEX-like disorders remain unknown. |
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A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They include immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, which is caused by mutations in forkhead box P3 (FOXP3), and IPEX-like disorders caused by mutations in IL-2 receptor α (IL2RA), signal transducer and activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT1). However, the genetic defects underlying many cases of IPEX-like disorders remain unknown. |
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