Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons

Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are unknown.

Gespeichert in:

Autor*in:	Gielen, Vera [verfasserIn] Sykes, Annemarie Zhu, Jie Chan, Brian Macintyre, Jonathan Regamey, Nicolas Kieninger, Elisabeth Gupta, Atul Shoemark, Amelia Bossley, Cara Davies, Jane Saglani, Sejal Walker, Patrick Nicholson, Sandra E. Dalpke, Alexander H. Kon, Onn-Min Bush, Andrew Johnston, Sebastian L. Edwards, Michael R.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	cytokine TH2 inflammation suppressor of cytokine signaling innate immunity atopy asthma exacerbation asthma interferon Rhinovirus

Umfang:	18635

Übergeordnetes Werk:	Enthalten in: Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward - Papakitsou, I. ELSEVIER, 2022, official publication of the American Academy of Allergy, Asthma and Immunology, Amsterdam [u.a.]
Übergeordnetes Werk:	volume:136 ; year:2015 ; number:1 ; pages:177-18811 ; extent:18635

Links:	Volltext

DOI / URN:	10.1016/j.jaci.2014.11.039

Katalog-ID:	ELV012734691

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allfields	10.1016/j.jaci.2014.11.039 doi GBVA2015001000030.pica (DE-627)ELV012734691 (ELSEVIER)S0091-6749(14)03667-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Gielen, Vera verfasserin aut Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons 2015 18635 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are unknown. cytokine Elsevier TH2 inflammation Elsevier suppressor of cytokine signaling Elsevier innate immunity Elsevier atopy Elsevier asthma exacerbation Elsevier asthma Elsevier interferon Elsevier Rhinovirus Elsevier Sykes, Annemarie oth Zhu, Jie oth Chan, Brian oth Macintyre, Jonathan oth Regamey, Nicolas oth Kieninger, Elisabeth oth Gupta, Atul oth Shoemark, Amelia oth Bossley, Cara oth Davies, Jane oth Saglani, Sejal oth Walker, Patrick oth Nicholson, Sandra E. oth Dalpke, Alexander H. oth Kon, Onn-Min oth Bush, Andrew oth Johnston, Sebastian L. oth Edwards, Michael R. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:136 year:2015 number:1 pages:177-18811 extent:18635 https://doi.org/10.1016/j.jaci.2014.11.039 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 136 2015 1 177-18811 18635 045F 610
spelling	10.1016/j.jaci.2014.11.039 doi GBVA2015001000030.pica (DE-627)ELV012734691 (ELSEVIER)S0091-6749(14)03667-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Gielen, Vera verfasserin aut Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons 2015 18635 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are unknown. cytokine Elsevier TH2 inflammation Elsevier suppressor of cytokine signaling Elsevier innate immunity Elsevier atopy Elsevier asthma exacerbation Elsevier asthma Elsevier interferon Elsevier Rhinovirus Elsevier Sykes, Annemarie oth Zhu, Jie oth Chan, Brian oth Macintyre, Jonathan oth Regamey, Nicolas oth Kieninger, Elisabeth oth Gupta, Atul oth Shoemark, Amelia oth Bossley, Cara oth Davies, Jane oth Saglani, Sejal oth Walker, Patrick oth Nicholson, Sandra E. oth Dalpke, Alexander H. oth Kon, Onn-Min oth Bush, Andrew oth Johnston, Sebastian L. oth Edwards, Michael R. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:136 year:2015 number:1 pages:177-18811 extent:18635 https://doi.org/10.1016/j.jaci.2014.11.039 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 136 2015 1 177-18811 18635 045F 610
allfields_unstemmed	10.1016/j.jaci.2014.11.039 doi GBVA2015001000030.pica (DE-627)ELV012734691 (ELSEVIER)S0091-6749(14)03667-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Gielen, Vera verfasserin aut Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons 2015 18635 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are unknown. cytokine Elsevier TH2 inflammation Elsevier suppressor of cytokine signaling Elsevier innate immunity Elsevier atopy Elsevier asthma exacerbation Elsevier asthma Elsevier interferon Elsevier Rhinovirus Elsevier Sykes, Annemarie oth Zhu, Jie oth Chan, Brian oth Macintyre, Jonathan oth Regamey, Nicolas oth Kieninger, Elisabeth oth Gupta, Atul oth Shoemark, Amelia oth Bossley, Cara oth Davies, Jane oth Saglani, Sejal oth Walker, Patrick oth Nicholson, Sandra E. oth Dalpke, Alexander H. oth Kon, Onn-Min oth Bush, Andrew oth Johnston, Sebastian L. oth Edwards, Michael R. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:136 year:2015 number:1 pages:177-18811 extent:18635 https://doi.org/10.1016/j.jaci.2014.11.039 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 136 2015 1 177-18811 18635 045F 610
allfieldsGer	10.1016/j.jaci.2014.11.039 doi GBVA2015001000030.pica (DE-627)ELV012734691 (ELSEVIER)S0091-6749(14)03667-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Gielen, Vera verfasserin aut Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons 2015 18635 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are unknown. cytokine Elsevier TH2 inflammation Elsevier suppressor of cytokine signaling Elsevier innate immunity Elsevier atopy Elsevier asthma exacerbation Elsevier asthma Elsevier interferon Elsevier Rhinovirus Elsevier Sykes, Annemarie oth Zhu, Jie oth Chan, Brian oth Macintyre, Jonathan oth Regamey, Nicolas oth Kieninger, Elisabeth oth Gupta, Atul oth Shoemark, Amelia oth Bossley, Cara oth Davies, Jane oth Saglani, Sejal oth Walker, Patrick oth Nicholson, Sandra E. oth Dalpke, Alexander H. oth Kon, Onn-Min oth Bush, Andrew oth Johnston, Sebastian L. oth Edwards, Michael R. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:136 year:2015 number:1 pages:177-18811 extent:18635 https://doi.org/10.1016/j.jaci.2014.11.039 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 136 2015 1 177-18811 18635 045F 610
allfieldsSound	10.1016/j.jaci.2014.11.039 doi GBVA2015001000030.pica (DE-627)ELV012734691 (ELSEVIER)S0091-6749(14)03667-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.85 bkl Gielen, Vera verfasserin aut Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons 2015 18635 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are unknown. cytokine Elsevier TH2 inflammation Elsevier suppressor of cytokine signaling Elsevier innate immunity Elsevier atopy Elsevier asthma exacerbation Elsevier asthma Elsevier interferon Elsevier Rhinovirus Elsevier Sykes, Annemarie oth Zhu, Jie oth Chan, Brian oth Macintyre, Jonathan oth Regamey, Nicolas oth Kieninger, Elisabeth oth Gupta, Atul oth Shoemark, Amelia oth Bossley, Cara oth Davies, Jane oth Saglani, Sejal oth Walker, Patrick oth Nicholson, Sandra E. oth Dalpke, Alexander H. oth Kon, Onn-Min oth Bush, Andrew oth Johnston, Sebastian L. oth Edwards, Michael R. oth Enthalten in Elsevier Papakitsou, I. ELSEVIER Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward 2022 official publication of the American Academy of Allergy, Asthma and Immunology Amsterdam [u.a.] (DE-627)ELV000021164 volume:136 year:2015 number:1 pages:177-18811 extent:18635 https://doi.org/10.1016/j.jaci.2014.11.039 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 136 2015 1 177-18811 18635 045F 610
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hierarchy_parent_title	Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward
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title	Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons
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title_full	Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons
author_sort	Gielen, Vera
journal	Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward
journalStr	Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward
lang_code	eng
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author-letter	Gielen, Vera
doi_str_mv	10.1016/j.jaci.2014.11.039
dewey-full	610
title_sort	increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons
title_auth	Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons
abstract	Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are unknown.
abstractGer	Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are unknown.
abstract_unstemmed	Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are unknown.
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title_short	Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons
url	https://doi.org/10.1016/j.jaci.2014.11.039
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author2	Sykes, Annemarie Zhu, Jie Chan, Brian Macintyre, Jonathan Regamey, Nicolas Kieninger, Elisabeth Gupta, Atul Shoemark, Amelia Bossley, Cara Davies, Jane Saglani, Sejal Walker, Patrick Nicholson, Sandra E. Dalpke, Alexander H. Kon, Onn-Min Bush, Andrew Johnston, Sebastian L. Edwards, Michael R.
author2Str	Sykes, Annemarie Zhu, Jie Chan, Brian Macintyre, Jonathan Regamey, Nicolas Kieninger, Elisabeth Gupta, Atul Shoemark, Amelia Bossley, Cara Davies, Jane Saglani, Sejal Walker, Patrick Nicholson, Sandra E. Dalpke, Alexander H. Kon, Onn-Min Bush, Andrew Johnston, Sebastian L. Edwards, Michael R.
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doi_str	10.1016/j.jaci.2014.11.039
up_date	2024-07-06T17:04:16.351Z
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