Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages

Asthma is a disease affecting more boys than girls in childhood and more women than men in adulthood. The mechanisms behind these sex-specific differences are not yet understood.

Gespeichert in:
Autor*in:

Schieck, Maximilian [verfasserIn]

Schouten, Jan P.

Michel, Sven

Suttner, Kathrin

Toncheva, Antoaneta A.

Gaertner, Vincent D.

Illig, Thomas

Lipinski, Simone

Franke, Andre

Klintschar, Michael

Kalayci, Omer

Sahiner, Umit M.

Birben, Esra

Melén, Erik

Pershagen, Göran

Freidin, Maxim B.

Ogorodova, Ludmila M.

Granell, Raquel

Henderson, John

Brunekreef, Bert

Smit, Henriëtte A.

Vogelberg, Christian

von Berg, Andrea

Bufe, Albrecht

Heinzmann, Andrea

Laub, Otto

Rietschel, Ernst

Simma, Burkhard

Genuneit, Jon

Jonigk, Danny

Postma, Dirkje S.

Koppelman, Gerard H.

Vonk, Judith M.

Timens, Wim

Boezen, H. Marike

Kabesch, Michael

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2016

Schlagwörter:

DMRT1

single nucleotide polymorphism

sex

genetic association

interaction

rs3812523

Asthma

Umfang:

11

Übergeordnetes Werk:

Enthalten in: Antidiabetic treatment in elderly patients with low performance status admitted to internal medicine ward - Papakitsou, I. ELSEVIER, 2022, official publication of the American Academy of Allergy, Asthma and Immunology, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:138 ; year:2016 ; number:2 ; pages:421-431 ; extent:11

Links:

Volltext

DOI / URN:

10.1016/j.jaci.2015.12.1305

Katalog-ID:

ELV013614584

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