The role of innate immunity in the immunopathology and treatment of HBV infection
In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Maini, Mala K. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016transfer abstract |
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| Schlagwörter: |
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| Umfang: |
11 |
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| Übergeordnetes Werk: |
Enthalten in: Identification of the antigenic region of - Abdelbaky, Hanan H. ELSEVIER, 2018, official journal of the European Association for the Study of the Liver, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:64 ; year:2016 ; number:1 ; pages:60-70 ; extent:11 |
| Links: |
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| DOI / URN: |
10.1016/j.jhep.2016.01.028 |
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| 520 | |a In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. | ||
| 520 | |a In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. | ||
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10.1016/j.jhep.2016.01.028 doi GBVA2016006000007.pica (DE-627)ELV013823582 (ELSEVIER)S0168-8278(16)00064-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.44 bkl Maini, Mala K. verfasserin aut The role of innate immunity in the immunopathology and treatment of HBV infection 2016transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. Monocytes Elsevier Innate immunotherapy Elsevier MDSC Elsevier HBV innate immunity Elsevier Interferon-alpha Elsevier Innate sensors Elsevier MAITs Elsevier Gehring, Adam J. oth Enthalten in Elsevier Science Abdelbaky, Hanan H. ELSEVIER Identification of the antigenic region of 2018 official journal of the European Association for the Study of the Liver Amsterdam [u.a.] (DE-627)ELV000433829 volume:64 year:2016 number:1 pages:60-70 extent:11 https://doi.org/10.1016/j.jhep.2016.01.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.44 Parasitologie Medizin VZ AR 64 2016 1 60-70 11 64.2016, 1, S60-, (11 S.) 045F 610 |
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10.1016/j.jhep.2016.01.028 doi GBVA2016006000007.pica (DE-627)ELV013823582 (ELSEVIER)S0168-8278(16)00064-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.44 bkl Maini, Mala K. verfasserin aut The role of innate immunity in the immunopathology and treatment of HBV infection 2016transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. Monocytes Elsevier Innate immunotherapy Elsevier MDSC Elsevier HBV innate immunity Elsevier Interferon-alpha Elsevier Innate sensors Elsevier MAITs Elsevier Gehring, Adam J. oth Enthalten in Elsevier Science Abdelbaky, Hanan H. ELSEVIER Identification of the antigenic region of 2018 official journal of the European Association for the Study of the Liver Amsterdam [u.a.] (DE-627)ELV000433829 volume:64 year:2016 number:1 pages:60-70 extent:11 https://doi.org/10.1016/j.jhep.2016.01.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.44 Parasitologie Medizin VZ AR 64 2016 1 60-70 11 64.2016, 1, S60-, (11 S.) 045F 610 |
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10.1016/j.jhep.2016.01.028 doi GBVA2016006000007.pica (DE-627)ELV013823582 (ELSEVIER)S0168-8278(16)00064-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.44 bkl Maini, Mala K. verfasserin aut The role of innate immunity in the immunopathology and treatment of HBV infection 2016transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. Monocytes Elsevier Innate immunotherapy Elsevier MDSC Elsevier HBV innate immunity Elsevier Interferon-alpha Elsevier Innate sensors Elsevier MAITs Elsevier Gehring, Adam J. oth Enthalten in Elsevier Science Abdelbaky, Hanan H. ELSEVIER Identification of the antigenic region of 2018 official journal of the European Association for the Study of the Liver Amsterdam [u.a.] (DE-627)ELV000433829 volume:64 year:2016 number:1 pages:60-70 extent:11 https://doi.org/10.1016/j.jhep.2016.01.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.44 Parasitologie Medizin VZ AR 64 2016 1 60-70 11 64.2016, 1, S60-, (11 S.) 045F 610 |
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10.1016/j.jhep.2016.01.028 doi GBVA2016006000007.pica (DE-627)ELV013823582 (ELSEVIER)S0168-8278(16)00064-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.44 bkl Maini, Mala K. verfasserin aut The role of innate immunity in the immunopathology and treatment of HBV infection 2016transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. Monocytes Elsevier Innate immunotherapy Elsevier MDSC Elsevier HBV innate immunity Elsevier Interferon-alpha Elsevier Innate sensors Elsevier MAITs Elsevier Gehring, Adam J. oth Enthalten in Elsevier Science Abdelbaky, Hanan H. ELSEVIER Identification of the antigenic region of 2018 official journal of the European Association for the Study of the Liver Amsterdam [u.a.] (DE-627)ELV000433829 volume:64 year:2016 number:1 pages:60-70 extent:11 https://doi.org/10.1016/j.jhep.2016.01.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.44 Parasitologie Medizin VZ AR 64 2016 1 60-70 11 64.2016, 1, S60-, (11 S.) 045F 610 |
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10.1016/j.jhep.2016.01.028 doi GBVA2016006000007.pica (DE-627)ELV013823582 (ELSEVIER)S0168-8278(16)00064-7 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.44 bkl Maini, Mala K. verfasserin aut The role of innate immunity in the immunopathology and treatment of HBV infection 2016transfer abstract 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. Monocytes Elsevier Innate immunotherapy Elsevier MDSC Elsevier HBV innate immunity Elsevier Interferon-alpha Elsevier Innate sensors Elsevier MAITs Elsevier Gehring, Adam J. oth Enthalten in Elsevier Science Abdelbaky, Hanan H. ELSEVIER Identification of the antigenic region of 2018 official journal of the European Association for the Study of the Liver Amsterdam [u.a.] (DE-627)ELV000433829 volume:64 year:2016 number:1 pages:60-70 extent:11 https://doi.org/10.1016/j.jhep.2016.01.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.44 Parasitologie Medizin VZ AR 64 2016 1 60-70 11 64.2016, 1, S60-, (11 S.) 045F 610 |
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role of innate immunity in the immunopathology and treatment of hbv infection |
| title_auth |
The role of innate immunity in the immunopathology and treatment of HBV infection |
| abstract |
In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. |
| abstractGer |
In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. |
| abstract_unstemmed |
In this review we give a brief update on sensors recently determined to be capable of detecting HBV, and examine how the virus represses the induction of pro-inflammatory cytokines like type I interferons. We overview cellular components of innate immunity that are present at high frequencies in the liver, and discuss their roles in HBV control and/or pathogenesis. We argue that many innate effectors have adaptive-like features or can exert specific effects on HBV through immunoregulation of T cells. Finally we consider current and possible future strategies to manipulate innate immunity as novel approaches towards a functional cure for HBV. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
| container_issue |
1 |
| title_short |
The role of innate immunity in the immunopathology and treatment of HBV infection |
| url |
https://doi.org/10.1016/j.jhep.2016.01.028 |
| remote_bool |
true |
| author2 |
Gehring, Adam J. |
| author2Str |
Gehring, Adam J. |
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| isOA_txt |
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| hochschulschrift_bool |
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| author2_role |
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| doi_str |
10.1016/j.jhep.2016.01.028 |
| up_date |
2024-07-06T19:53:15.654Z |
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7.3995857 |