CITALOPRAM PULSE-LOADING FOR TREATMENT-RESITANT OBSESSIVE-COMPULSIVE DISORDER: PRELIMINARY DATA FROM AN OPEN-LABEL TRIAL
Treatment resistance is a frequent situation in Obsessive Compulsive Disorder (OCD), occurring in 40–60% of patients. However, in the current literature there are only a few evidence-based options for treatment resistant patients. Pulse-loading treatment consists in a rapid titration of the pharmaco...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Grassi, Giacomo [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016transfer abstract |
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| Umfang: |
2 |
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| Übergeordnetes Werk: |
Enthalten in: Temperature-dependence laws of absorption line shape parameters of the CO - Wilzewski, J.S. ELSEVIER, 2017, ENP : the journal of the European College of Neuropsychopharmacology, Amsterdam |
|---|---|
| Übergeordnetes Werk: |
volume:26 ; year:2016 ; number:5 ; pages:898-899 ; extent:2 |
| Links: |
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| DOI / URN: |
10.1016/j.euroneuro.2015.06.034 |
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| 520 | |a Treatment resistance is a frequent situation in Obsessive Compulsive Disorder (OCD), occurring in 40–60% of patients. However, in the current literature there are only a few evidence-based options for treatment resistant patients. Pulse-loading treatment consists in a rapid titration of the pharmacological agent in the first days of treatment. A few studies suggested that this kind of titration with intravenous clomipramine could result in a greater and faster response than with a standard titration in OCD resistant patients (Koran et al., 2006; Grassi et al., 2013). The aim of this open-label trial was to investigate the effectiveness and tolerability of a citalopram pulse-loading protocol in severe treatment-resistant OCD patients. | ||
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10.1016/j.euroneuro.2015.06.034 doi GBVA2016014000027.pica (DE-627)ELV014235102 (ELSEVIER)S0924-977X(15)00204-7 DE-627 ger DE-627 rakwb eng 150 610 150 DE-600 610 DE-600 530 VZ 33.00 bkl Grassi, Giacomo verfasserin aut CITALOPRAM PULSE-LOADING FOR TREATMENT-RESITANT OBSESSIVE-COMPULSIVE DISORDER: PRELIMINARY DATA FROM AN OPEN-LABEL TRIAL 2016transfer abstract 2 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Treatment resistance is a frequent situation in Obsessive Compulsive Disorder (OCD), occurring in 40–60% of patients. However, in the current literature there are only a few evidence-based options for treatment resistant patients. Pulse-loading treatment consists in a rapid titration of the pharmacological agent in the first days of treatment. A few studies suggested that this kind of titration with intravenous clomipramine could result in a greater and faster response than with a standard titration in OCD resistant patients (Koran et al., 2006; Grassi et al., 2013). The aim of this open-label trial was to investigate the effectiveness and tolerability of a citalopram pulse-loading protocol in severe treatment-resistant OCD patients. Treatment resistance is a frequent situation in Obsessive Compulsive Disorder (OCD), occurring in 40–60% of patients. However, in the current literature there are only a few evidence-based options for treatment resistant patients. Pulse-loading treatment consists in a rapid titration of the pharmacological agent in the first days of treatment. A few studies suggested that this kind of titration with intravenous clomipramine could result in a greater and faster response than with a standard titration in OCD resistant patients (Koran et al., 2006; Grassi et al., 2013). The aim of this open-label trial was to investigate the effectiveness and tolerability of a citalopram pulse-loading protocol in severe treatment-resistant OCD patients. Pallanti, Stefano oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:26 year:2016 number:5 pages:898-899 extent:2 https://doi.org/10.1016/j.euroneuro.2015.06.034 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 26 2016 5 898-899 2 045F 150 |
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10.1016/j.euroneuro.2015.06.034 doi GBVA2016014000027.pica (DE-627)ELV014235102 (ELSEVIER)S0924-977X(15)00204-7 DE-627 ger DE-627 rakwb eng 150 610 150 DE-600 610 DE-600 530 VZ 33.00 bkl Grassi, Giacomo verfasserin aut CITALOPRAM PULSE-LOADING FOR TREATMENT-RESITANT OBSESSIVE-COMPULSIVE DISORDER: PRELIMINARY DATA FROM AN OPEN-LABEL TRIAL 2016transfer abstract 2 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Treatment resistance is a frequent situation in Obsessive Compulsive Disorder (OCD), occurring in 40–60% of patients. However, in the current literature there are only a few evidence-based options for treatment resistant patients. Pulse-loading treatment consists in a rapid titration of the pharmacological agent in the first days of treatment. A few studies suggested that this kind of titration with intravenous clomipramine could result in a greater and faster response than with a standard titration in OCD resistant patients (Koran et al., 2006; Grassi et al., 2013). The aim of this open-label trial was to investigate the effectiveness and tolerability of a citalopram pulse-loading protocol in severe treatment-resistant OCD patients. Treatment resistance is a frequent situation in Obsessive Compulsive Disorder (OCD), occurring in 40–60% of patients. However, in the current literature there are only a few evidence-based options for treatment resistant patients. Pulse-loading treatment consists in a rapid titration of the pharmacological agent in the first days of treatment. A few studies suggested that this kind of titration with intravenous clomipramine could result in a greater and faster response than with a standard titration in OCD resistant patients (Koran et al., 2006; Grassi et al., 2013). The aim of this open-label trial was to investigate the effectiveness and tolerability of a citalopram pulse-loading protocol in severe treatment-resistant OCD patients. Pallanti, Stefano oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:26 year:2016 number:5 pages:898-899 extent:2 https://doi.org/10.1016/j.euroneuro.2015.06.034 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 26 2016 5 898-899 2 045F 150 |
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citalopram pulse-loading for treatment-resitant obsessive-compulsive disorder: preliminary data from an open-label trial |
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CITALOPRAM PULSE-LOADING FOR TREATMENT-RESITANT OBSESSIVE-COMPULSIVE DISORDER: PRELIMINARY DATA FROM AN OPEN-LABEL TRIAL |
| abstract |
Treatment resistance is a frequent situation in Obsessive Compulsive Disorder (OCD), occurring in 40–60% of patients. However, in the current literature there are only a few evidence-based options for treatment resistant patients. Pulse-loading treatment consists in a rapid titration of the pharmacological agent in the first days of treatment. A few studies suggested that this kind of titration with intravenous clomipramine could result in a greater and faster response than with a standard titration in OCD resistant patients (Koran et al., 2006; Grassi et al., 2013). The aim of this open-label trial was to investigate the effectiveness and tolerability of a citalopram pulse-loading protocol in severe treatment-resistant OCD patients. |
| abstractGer |
Treatment resistance is a frequent situation in Obsessive Compulsive Disorder (OCD), occurring in 40–60% of patients. However, in the current literature there are only a few evidence-based options for treatment resistant patients. Pulse-loading treatment consists in a rapid titration of the pharmacological agent in the first days of treatment. A few studies suggested that this kind of titration with intravenous clomipramine could result in a greater and faster response than with a standard titration in OCD resistant patients (Koran et al., 2006; Grassi et al., 2013). The aim of this open-label trial was to investigate the effectiveness and tolerability of a citalopram pulse-loading protocol in severe treatment-resistant OCD patients. |
| abstract_unstemmed |
Treatment resistance is a frequent situation in Obsessive Compulsive Disorder (OCD), occurring in 40–60% of patients. However, in the current literature there are only a few evidence-based options for treatment resistant patients. Pulse-loading treatment consists in a rapid titration of the pharmacological agent in the first days of treatment. A few studies suggested that this kind of titration with intravenous clomipramine could result in a greater and faster response than with a standard titration in OCD resistant patients (Koran et al., 2006; Grassi et al., 2013). The aim of this open-label trial was to investigate the effectiveness and tolerability of a citalopram pulse-loading protocol in severe treatment-resistant OCD patients. |
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CITALOPRAM PULSE-LOADING FOR TREATMENT-RESITANT OBSESSIVE-COMPULSIVE DISORDER: PRELIMINARY DATA FROM AN OPEN-LABEL TRIAL |
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https://doi.org/10.1016/j.euroneuro.2015.06.034 |
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