Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients
Several studies suggest that pathological changes in Alzheimer’s disease (AD) brain begin around 10–20 years before the onset of cognitive impairment. Biomarkers that can support early diagnosis and predict development of dementia would, therefore, be crucial for patient care and evaluation of drug...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Di Domenico, Fabio [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Umfang: |
9 |
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| Übergeordnetes Werk: |
Enthalten in: New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells - Wu, Zhi-Sheng ELSEVIER, 2020, the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research, New York, NY [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:91 ; year:2016 ; pages:1-9 ; extent:9 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.freeradbiomed.2015.12.004 |
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10.1016/j.freeradbiomed.2015.12.004 doi GBVA2016015000008.pica (DE-627)ELV014277182 (ELSEVIER)S0891-5849(15)01146-6 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Di Domenico, Fabio verfasserin aut Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients 2016 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Several studies suggest that pathological changes in Alzheimer’s disease (AD) brain begin around 10–20 years before the onset of cognitive impairment. Biomarkers that can support early diagnosis and predict development of dementia would, therefore, be crucial for patient care and evaluation of drug efficacy. Although cerebrospinal fluid (CSF) levels of Aβ42, tau, and p-tau are well-established diagnostic biomarkers of AD, there is an urgent need to identify additional molecular alterations of neuronal function that can be evaluated at the systemic level. Redox proteomics Elsevier Protein oxidation Elsevier CSF Elsevier Biomarkers Elsevier Extracellular chaperones Elsevier APOE Elsevier Pupo, Gilda oth Giraldo, Esther oth Badìa, Mari-Carmen oth Monllor, Paloma oth Lloret, Ana oth Eugenia Schininà, Maria oth Giorgi, Alessandra oth Cini, Chiara oth Tramutola, Antonella oth Butterfield, D. Allan oth Viña, José oth Perluigi, Marzia oth Enthalten in Elsevier Wu, Zhi-Sheng ELSEVIER New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells 2020 the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research New York, NY [u.a.] (DE-627)ELV003689417 volume:91 year:2016 pages:1-9 extent:9 https://doi.org/10.1016/j.freeradbiomed.2015.12.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 52.57 Energiespeicherung VZ 53.36 Energiedirektumwandler elektrische Energiespeicher VZ AR 91 2016 1-9 9 045F 570 |
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10.1016/j.freeradbiomed.2015.12.004 doi GBVA2016015000008.pica (DE-627)ELV014277182 (ELSEVIER)S0891-5849(15)01146-6 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Di Domenico, Fabio verfasserin aut Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients 2016 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Several studies suggest that pathological changes in Alzheimer’s disease (AD) brain begin around 10–20 years before the onset of cognitive impairment. Biomarkers that can support early diagnosis and predict development of dementia would, therefore, be crucial for patient care and evaluation of drug efficacy. Although cerebrospinal fluid (CSF) levels of Aβ42, tau, and p-tau are well-established diagnostic biomarkers of AD, there is an urgent need to identify additional molecular alterations of neuronal function that can be evaluated at the systemic level. Redox proteomics Elsevier Protein oxidation Elsevier CSF Elsevier Biomarkers Elsevier Extracellular chaperones Elsevier APOE Elsevier Pupo, Gilda oth Giraldo, Esther oth Badìa, Mari-Carmen oth Monllor, Paloma oth Lloret, Ana oth Eugenia Schininà, Maria oth Giorgi, Alessandra oth Cini, Chiara oth Tramutola, Antonella oth Butterfield, D. Allan oth Viña, José oth Perluigi, Marzia oth Enthalten in Elsevier Wu, Zhi-Sheng ELSEVIER New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells 2020 the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research New York, NY [u.a.] (DE-627)ELV003689417 volume:91 year:2016 pages:1-9 extent:9 https://doi.org/10.1016/j.freeradbiomed.2015.12.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 52.57 Energiespeicherung VZ 53.36 Energiedirektumwandler elektrische Energiespeicher VZ AR 91 2016 1-9 9 045F 570 |
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10.1016/j.freeradbiomed.2015.12.004 doi GBVA2016015000008.pica (DE-627)ELV014277182 (ELSEVIER)S0891-5849(15)01146-6 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Di Domenico, Fabio verfasserin aut Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients 2016 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Several studies suggest that pathological changes in Alzheimer’s disease (AD) brain begin around 10–20 years before the onset of cognitive impairment. Biomarkers that can support early diagnosis and predict development of dementia would, therefore, be crucial for patient care and evaluation of drug efficacy. Although cerebrospinal fluid (CSF) levels of Aβ42, tau, and p-tau are well-established diagnostic biomarkers of AD, there is an urgent need to identify additional molecular alterations of neuronal function that can be evaluated at the systemic level. Redox proteomics Elsevier Protein oxidation Elsevier CSF Elsevier Biomarkers Elsevier Extracellular chaperones Elsevier APOE Elsevier Pupo, Gilda oth Giraldo, Esther oth Badìa, Mari-Carmen oth Monllor, Paloma oth Lloret, Ana oth Eugenia Schininà, Maria oth Giorgi, Alessandra oth Cini, Chiara oth Tramutola, Antonella oth Butterfield, D. Allan oth Viña, José oth Perluigi, Marzia oth Enthalten in Elsevier Wu, Zhi-Sheng ELSEVIER New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells 2020 the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research New York, NY [u.a.] (DE-627)ELV003689417 volume:91 year:2016 pages:1-9 extent:9 https://doi.org/10.1016/j.freeradbiomed.2015.12.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 52.57 Energiespeicherung VZ 53.36 Energiedirektumwandler elektrische Energiespeicher VZ AR 91 2016 1-9 9 045F 570 |
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10.1016/j.freeradbiomed.2015.12.004 doi GBVA2016015000008.pica (DE-627)ELV014277182 (ELSEVIER)S0891-5849(15)01146-6 DE-627 ger DE-627 rakwb eng 570 610 570 DE-600 610 DE-600 620 VZ 52.57 bkl 53.36 bkl Di Domenico, Fabio verfasserin aut Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients 2016 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Several studies suggest that pathological changes in Alzheimer’s disease (AD) brain begin around 10–20 years before the onset of cognitive impairment. Biomarkers that can support early diagnosis and predict development of dementia would, therefore, be crucial for patient care and evaluation of drug efficacy. Although cerebrospinal fluid (CSF) levels of Aβ42, tau, and p-tau are well-established diagnostic biomarkers of AD, there is an urgent need to identify additional molecular alterations of neuronal function that can be evaluated at the systemic level. Redox proteomics Elsevier Protein oxidation Elsevier CSF Elsevier Biomarkers Elsevier Extracellular chaperones Elsevier APOE Elsevier Pupo, Gilda oth Giraldo, Esther oth Badìa, Mari-Carmen oth Monllor, Paloma oth Lloret, Ana oth Eugenia Schininà, Maria oth Giorgi, Alessandra oth Cini, Chiara oth Tramutola, Antonella oth Butterfield, D. Allan oth Viña, José oth Perluigi, Marzia oth Enthalten in Elsevier Wu, Zhi-Sheng ELSEVIER New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells 2020 the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research New York, NY [u.a.] (DE-627)ELV003689417 volume:91 year:2016 pages:1-9 extent:9 https://doi.org/10.1016/j.freeradbiomed.2015.12.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 52.57 Energiespeicherung VZ 53.36 Energiedirektumwandler elektrische Energiespeicher VZ AR 91 2016 1-9 9 045F 570 |
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New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells |
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New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells |
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Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients |
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Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients |
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Di Domenico, Fabio |
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New organic dyes with varied arylamine donors as effective co-sensitizers for ruthenium complex N719 in dye sensitized solar cells |
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oxidative signature of cerebrospinal fluid from mild cognitive impairment and alzheimer disease patients |
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Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients |
| abstract |
Several studies suggest that pathological changes in Alzheimer’s disease (AD) brain begin around 10–20 years before the onset of cognitive impairment. Biomarkers that can support early diagnosis and predict development of dementia would, therefore, be crucial for patient care and evaluation of drug efficacy. Although cerebrospinal fluid (CSF) levels of Aβ42, tau, and p-tau are well-established diagnostic biomarkers of AD, there is an urgent need to identify additional molecular alterations of neuronal function that can be evaluated at the systemic level. |
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Several studies suggest that pathological changes in Alzheimer’s disease (AD) brain begin around 10–20 years before the onset of cognitive impairment. Biomarkers that can support early diagnosis and predict development of dementia would, therefore, be crucial for patient care and evaluation of drug efficacy. Although cerebrospinal fluid (CSF) levels of Aβ42, tau, and p-tau are well-established diagnostic biomarkers of AD, there is an urgent need to identify additional molecular alterations of neuronal function that can be evaluated at the systemic level. |
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Several studies suggest that pathological changes in Alzheimer’s disease (AD) brain begin around 10–20 years before the onset of cognitive impairment. Biomarkers that can support early diagnosis and predict development of dementia would, therefore, be crucial for patient care and evaluation of drug efficacy. Although cerebrospinal fluid (CSF) levels of Aβ42, tau, and p-tau are well-established diagnostic biomarkers of AD, there is an urgent need to identify additional molecular alterations of neuronal function that can be evaluated at the systemic level. |
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Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients |
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Pupo, Gilda Giraldo, Esther Badìa, Mari-Carmen Monllor, Paloma Lloret, Ana Eugenia Schininà, Maria Giorgi, Alessandra Cini, Chiara Tramutola, Antonella Butterfield, D. Allan Viña, José Perluigi, Marzia |
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Pupo, Gilda Giraldo, Esther Badìa, Mari-Carmen Monllor, Paloma Lloret, Ana Eugenia Schininà, Maria Giorgi, Alessandra Cini, Chiara Tramutola, Antonella Butterfield, D. Allan Viña, José Perluigi, Marzia |
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