Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration
An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of...
Ausführliche Beschreibung
Autor*in: |
Trunec, Martin [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2017transfer abstract |
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9 |
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Übergeordnetes Werk: |
Enthalten in: Soil and water bioengineering: Practice and research needs for reconciling natural hazard control and ecological restoration - Rey, F. ELSEVIER, 2018, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:43 ; year:2017 ; number:14 ; day:1 ; month:10 ; pages:11265-11273 ; extent:9 |
Links: |
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DOI / URN: |
10.1016/j.ceramint.2017.05.177 |
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ELV014998017 |
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520 | |a An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. | ||
520 | |a An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. | ||
650 | 7 | |a Milling (A) |2 Elsevier | |
650 | 7 | |a Biopmedical properties (E) |2 Elsevier | |
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10.1016/j.ceramint.2017.05.177 doi GBV00000000000375.pica (DE-627)ELV014998017 (ELSEVIER)S0272-8842(17)30990-2 DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Trunec, Martin verfasserin aut Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. Milling (A) Elsevier Biopmedical properties (E) Elsevier Porosity (B) Elsevier Scaffold Elsevier Apatite (D) Elsevier Chlup, Zdenek oth Enthalten in Elsevier Science Rey, F. ELSEVIER Soil and water bioengineering: Practice and research needs for reconciling natural hazard control and ecological restoration 2018 Amsterdam [u.a.] (DE-627)ELV000899798 volume:43 year:2017 number:14 day:1 month:10 pages:11265-11273 extent:9 https://doi.org/10.1016/j.ceramint.2017.05.177 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 43 2017 14 1 1001 11265-11273 9 |
spelling |
10.1016/j.ceramint.2017.05.177 doi GBV00000000000375.pica (DE-627)ELV014998017 (ELSEVIER)S0272-8842(17)30990-2 DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Trunec, Martin verfasserin aut Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. Milling (A) Elsevier Biopmedical properties (E) Elsevier Porosity (B) Elsevier Scaffold Elsevier Apatite (D) Elsevier Chlup, Zdenek oth Enthalten in Elsevier Science Rey, F. ELSEVIER Soil and water bioengineering: Practice and research needs for reconciling natural hazard control and ecological restoration 2018 Amsterdam [u.a.] (DE-627)ELV000899798 volume:43 year:2017 number:14 day:1 month:10 pages:11265-11273 extent:9 https://doi.org/10.1016/j.ceramint.2017.05.177 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 43 2017 14 1 1001 11265-11273 9 |
allfields_unstemmed |
10.1016/j.ceramint.2017.05.177 doi GBV00000000000375.pica (DE-627)ELV014998017 (ELSEVIER)S0272-8842(17)30990-2 DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Trunec, Martin verfasserin aut Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. Milling (A) Elsevier Biopmedical properties (E) Elsevier Porosity (B) Elsevier Scaffold Elsevier Apatite (D) Elsevier Chlup, Zdenek oth Enthalten in Elsevier Science Rey, F. ELSEVIER Soil and water bioengineering: Practice and research needs for reconciling natural hazard control and ecological restoration 2018 Amsterdam [u.a.] (DE-627)ELV000899798 volume:43 year:2017 number:14 day:1 month:10 pages:11265-11273 extent:9 https://doi.org/10.1016/j.ceramint.2017.05.177 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 43 2017 14 1 1001 11265-11273 9 |
allfieldsGer |
10.1016/j.ceramint.2017.05.177 doi GBV00000000000375.pica (DE-627)ELV014998017 (ELSEVIER)S0272-8842(17)30990-2 DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Trunec, Martin verfasserin aut Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. Milling (A) Elsevier Biopmedical properties (E) Elsevier Porosity (B) Elsevier Scaffold Elsevier Apatite (D) Elsevier Chlup, Zdenek oth Enthalten in Elsevier Science Rey, F. ELSEVIER Soil and water bioengineering: Practice and research needs for reconciling natural hazard control and ecological restoration 2018 Amsterdam [u.a.] (DE-627)ELV000899798 volume:43 year:2017 number:14 day:1 month:10 pages:11265-11273 extent:9 https://doi.org/10.1016/j.ceramint.2017.05.177 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 43 2017 14 1 1001 11265-11273 9 |
allfieldsSound |
10.1016/j.ceramint.2017.05.177 doi GBV00000000000375.pica (DE-627)ELV014998017 (ELSEVIER)S0272-8842(17)30990-2 DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.12 bkl 43.13 bkl 44.13 bkl Trunec, Martin verfasserin aut Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. Milling (A) Elsevier Biopmedical properties (E) Elsevier Porosity (B) Elsevier Scaffold Elsevier Apatite (D) Elsevier Chlup, Zdenek oth Enthalten in Elsevier Science Rey, F. ELSEVIER Soil and water bioengineering: Practice and research needs for reconciling natural hazard control and ecological restoration 2018 Amsterdam [u.a.] (DE-627)ELV000899798 volume:43 year:2017 number:14 day:1 month:10 pages:11265-11273 extent:9 https://doi.org/10.1016/j.ceramint.2017.05.177 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-GGO 43.12 Umweltchemie VZ 43.13 Umwelttoxikologie VZ 44.13 Medizinische Ökologie VZ AR 43 2017 14 1 1001 11265-11273 9 |
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Enthalten in Soil and water bioengineering: Practice and research needs for reconciling natural hazard control and ecological restoration Amsterdam [u.a.] volume:43 year:2017 number:14 day:1 month:10 pages:11265-11273 extent:9 |
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Enthalten in Soil and water bioengineering: Practice and research needs for reconciling natural hazard control and ecological restoration Amsterdam [u.a.] volume:43 year:2017 number:14 day:1 month:10 pages:11265-11273 extent:9 |
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An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. |
abstractGer |
An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. |
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An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613µm, which were connected through windows with an average diameter of 161µm. The compressive strength of the sintered foam reached an average value of 2MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100°C. The milling process was demonstrated and scaffold examples were successfully manufactured. |
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