Nanomaterials for delivery of nucleic acid to the central nervous system (CNS)
Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-rel...
Ausführliche Beschreibung
Autor*in: |
Wang, Danyang [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2017transfer abstract |
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Umfang: |
8 |
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Übergeordnetes Werk: |
Enthalten in: Adsorption of various metals by carboxymethyl-β-cyclodextrin-modified Zn - Kameda, Tomohito ELSEVIER, 2020, Amsterdam |
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Übergeordnetes Werk: |
volume:70 ; year:2017 ; day:1 ; month:01 ; pages:1039-1046 ; extent:8 |
Links: |
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DOI / URN: |
10.1016/j.msec.2016.04.011 |
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520 | |a Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. | ||
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10.1016/j.msec.2016.04.011 doi GBVA2017015000007.pica (DE-627)ELV015243982 (ELSEVIER)S0928-4931(16)30310-1 DE-627 ger DE-627 rakwb eng 600 600 DE-600 550 VZ 38.30 bkl 58.45 bkl 38.69 bkl 56.20 bkl Wang, Danyang verfasserin aut Nanomaterials for delivery of nucleic acid to the central nervous system (CNS) 2017transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Wu, Lin-Ping oth Enthalten in Elsevier Kameda, Tomohito ELSEVIER Adsorption of various metals by carboxymethyl-β-cyclodextrin-modified Zn 2020 Amsterdam (DE-627)ELV003774007 volume:70 year:2017 day:1 month:01 pages:1039-1046 extent:8 https://doi.org/10.1016/j.msec.2016.04.011 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 38.30 Mineralogie VZ 58.45 Gesteinshüttenkunde VZ 38.69 Bodenkunde: Sonstiges Geowissenschaften VZ 56.20 Ingenieurgeologie Bodenmechanik VZ AR 70 2017 1 0101 1039-1046 8 045F 600 |
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10.1016/j.msec.2016.04.011 doi GBVA2017015000007.pica (DE-627)ELV015243982 (ELSEVIER)S0928-4931(16)30310-1 DE-627 ger DE-627 rakwb eng 600 600 DE-600 550 VZ 38.30 bkl 58.45 bkl 38.69 bkl 56.20 bkl Wang, Danyang verfasserin aut Nanomaterials for delivery of nucleic acid to the central nervous system (CNS) 2017transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Wu, Lin-Ping oth Enthalten in Elsevier Kameda, Tomohito ELSEVIER Adsorption of various metals by carboxymethyl-β-cyclodextrin-modified Zn 2020 Amsterdam (DE-627)ELV003774007 volume:70 year:2017 day:1 month:01 pages:1039-1046 extent:8 https://doi.org/10.1016/j.msec.2016.04.011 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 38.30 Mineralogie VZ 58.45 Gesteinshüttenkunde VZ 38.69 Bodenkunde: Sonstiges Geowissenschaften VZ 56.20 Ingenieurgeologie Bodenmechanik VZ AR 70 2017 1 0101 1039-1046 8 045F 600 |
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10.1016/j.msec.2016.04.011 doi GBVA2017015000007.pica (DE-627)ELV015243982 (ELSEVIER)S0928-4931(16)30310-1 DE-627 ger DE-627 rakwb eng 600 600 DE-600 550 VZ 38.30 bkl 58.45 bkl 38.69 bkl 56.20 bkl Wang, Danyang verfasserin aut Nanomaterials for delivery of nucleic acid to the central nervous system (CNS) 2017transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Wu, Lin-Ping oth Enthalten in Elsevier Kameda, Tomohito ELSEVIER Adsorption of various metals by carboxymethyl-β-cyclodextrin-modified Zn 2020 Amsterdam (DE-627)ELV003774007 volume:70 year:2017 day:1 month:01 pages:1039-1046 extent:8 https://doi.org/10.1016/j.msec.2016.04.011 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 38.30 Mineralogie VZ 58.45 Gesteinshüttenkunde VZ 38.69 Bodenkunde: Sonstiges Geowissenschaften VZ 56.20 Ingenieurgeologie Bodenmechanik VZ AR 70 2017 1 0101 1039-1046 8 045F 600 |
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10.1016/j.msec.2016.04.011 doi GBVA2017015000007.pica (DE-627)ELV015243982 (ELSEVIER)S0928-4931(16)30310-1 DE-627 ger DE-627 rakwb eng 600 600 DE-600 550 VZ 38.30 bkl 58.45 bkl 38.69 bkl 56.20 bkl Wang, Danyang verfasserin aut Nanomaterials for delivery of nucleic acid to the central nervous system (CNS) 2017transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Wu, Lin-Ping oth Enthalten in Elsevier Kameda, Tomohito ELSEVIER Adsorption of various metals by carboxymethyl-β-cyclodextrin-modified Zn 2020 Amsterdam (DE-627)ELV003774007 volume:70 year:2017 day:1 month:01 pages:1039-1046 extent:8 https://doi.org/10.1016/j.msec.2016.04.011 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 38.30 Mineralogie VZ 58.45 Gesteinshüttenkunde VZ 38.69 Bodenkunde: Sonstiges Geowissenschaften VZ 56.20 Ingenieurgeologie Bodenmechanik VZ AR 70 2017 1 0101 1039-1046 8 045F 600 |
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10.1016/j.msec.2016.04.011 doi GBVA2017015000007.pica (DE-627)ELV015243982 (ELSEVIER)S0928-4931(16)30310-1 DE-627 ger DE-627 rakwb eng 600 600 DE-600 550 VZ 38.30 bkl 58.45 bkl 38.69 bkl 56.20 bkl Wang, Danyang verfasserin aut Nanomaterials for delivery of nucleic acid to the central nervous system (CNS) 2017transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. Wu, Lin-Ping oth Enthalten in Elsevier Kameda, Tomohito ELSEVIER Adsorption of various metals by carboxymethyl-β-cyclodextrin-modified Zn 2020 Amsterdam (DE-627)ELV003774007 volume:70 year:2017 day:1 month:01 pages:1039-1046 extent:8 https://doi.org/10.1016/j.msec.2016.04.011 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 38.30 Mineralogie VZ 58.45 Gesteinshüttenkunde VZ 38.69 Bodenkunde: Sonstiges Geowissenschaften VZ 56.20 Ingenieurgeologie Bodenmechanik VZ AR 70 2017 1 0101 1039-1046 8 045F 600 |
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title_sort |
nanomaterials for delivery of nucleic acid to the central nervous system (cns) |
title_auth |
Nanomaterials for delivery of nucleic acid to the central nervous system (CNS) |
abstract |
Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. |
abstractGer |
Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. |
abstract_unstemmed |
Billions of dollars have been invested in the therapeutic application of nucleic acid-based agents in humans in recent years. There are inspirable data from ongoing clinical trial for different diseases. However, in order to widely apply nucleic acid in prevention, diagnosis and treatment of age-related disease, such as neurodegeneration and disorders, suitable, safe and effective drug delivery nanocarriers have to been developed to overcome the blood brain barrier (BBB), which is the most inflexible barrier in human body. Here, we highlight the structure and function of barriers in the central nervous system (CNS) and summary several types of nanomaterials which can be potentially used in the brain delivery nucleic acid. |
collection_details |
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title_short |
Nanomaterials for delivery of nucleic acid to the central nervous system (CNS) |
url |
https://doi.org/10.1016/j.msec.2016.04.011 |
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Wu, Lin-Ping |
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10.1016/j.msec.2016.04.011 |
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2024-07-06T17:08:58.971Z |
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