Downregulation of adipose triglyceride lipase in the heart aggravates diabetic cardiomyopathy in db/db mice

• Mutations in ATGL or CGI-58 genes are associated with myocardial TG accumulation. • Lipid deposition was significantly higher in the hearts of db/db mice. • ATGL and CGI-58 expression was decreased in the hearts of db/db mice. • Reduced ATGL and CGI-58 expression may induce myocardial steatosis in...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Inoue, Tomoaki [verfasserIn]

Kobayashi, Kunihisa

Inoguchi, Toyoshi

Sonoda, Noriyuki

Maeda, Yasutaka

Hirata, Eiichi

Fujimura, Yoshinori

Miura, Daisuke

Hirano, Ken-ichi

Takayanagi, Ryoichi

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2013

Schlagwörter:

Adipose triglyceride lipase

Myocardial steatosis

Protein kinase C

Comparative gene identification-58

Diabetic cardiomyopathy

Umfang:

6

Übergeordnetes Werk:

Enthalten in: Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag - Zhang, Zhikun ELSEVIER, 2019, BBRC, Orlando, Fla

Übergeordnetes Werk:

volume:438 ; year:2013 ; number:1 ; day:16 ; month:08 ; pages:224-229 ; extent:6

Links:

Volltext

DOI / URN:

10.1016/j.bbrc.2013.07.063

Katalog-ID:

ELV017070953

Nicht das Richtige dabei?

Schreiben Sie uns!