Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice
This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti...
Ausführliche Beschreibung
Autor*in: |
Katzav, Aviva [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2014transfer abstract |
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Umfang: |
6 |
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Übergeordnetes Werk: |
Enthalten in: Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process - Li, Kuo ELSEVIER, 2020, official journal of the International Society for Neuroimmunology, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:272 ; year:2014 ; number:1 ; day:15 ; month:07 ; pages:10-15 ; extent:6 |
Links: |
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DOI / URN: |
10.1016/j.jneuroim.2014.04.003 |
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ELV017358752 |
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520 | |a This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. | ||
520 | |a This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. | ||
700 | 1 | |a Ben-Ziv, Tal |4 oth | |
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700 | 1 | |a Pick, Chaim G. |4 oth | |
700 | 1 | |a Shoenfeld, Yehuda |4 oth | |
700 | 1 | |a Chapman, Joab |4 oth | |
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10.1016/j.jneuroim.2014.04.003 doi GBVA2014005000014.pica (DE-627)ELV017358752 (ELSEVIER)S0165-5728(14)00099-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 530 VZ 43.13 bkl 50.17 bkl 58.53 bkl Katzav, Aviva verfasserin aut Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. Ben-Ziv, Tal oth Blank, Miri oth Pick, Chaim G. oth Shoenfeld, Yehuda oth Chapman, Joab oth Enthalten in Elsevier Science Li, Kuo ELSEVIER Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process 2020 official journal of the International Society for Neuroimmunology Amsterdam [u.a.] (DE-627)ELV005164184 volume:272 year:2014 number:1 day:15 month:07 pages:10-15 extent:6 https://doi.org/10.1016/j.jneuroim.2014.04.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 43.13 Umwelttoxikologie VZ 50.17 Sicherheitstechnik VZ 58.53 Abfallwirtschaft VZ AR 272 2014 1 15 0715 10-15 6 045F 610 |
spelling |
10.1016/j.jneuroim.2014.04.003 doi GBVA2014005000014.pica (DE-627)ELV017358752 (ELSEVIER)S0165-5728(14)00099-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 530 VZ 43.13 bkl 50.17 bkl 58.53 bkl Katzav, Aviva verfasserin aut Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. Ben-Ziv, Tal oth Blank, Miri oth Pick, Chaim G. oth Shoenfeld, Yehuda oth Chapman, Joab oth Enthalten in Elsevier Science Li, Kuo ELSEVIER Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process 2020 official journal of the International Society for Neuroimmunology Amsterdam [u.a.] (DE-627)ELV005164184 volume:272 year:2014 number:1 day:15 month:07 pages:10-15 extent:6 https://doi.org/10.1016/j.jneuroim.2014.04.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 43.13 Umwelttoxikologie VZ 50.17 Sicherheitstechnik VZ 58.53 Abfallwirtschaft VZ AR 272 2014 1 15 0715 10-15 6 045F 610 |
allfields_unstemmed |
10.1016/j.jneuroim.2014.04.003 doi GBVA2014005000014.pica (DE-627)ELV017358752 (ELSEVIER)S0165-5728(14)00099-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 530 VZ 43.13 bkl 50.17 bkl 58.53 bkl Katzav, Aviva verfasserin aut Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. Ben-Ziv, Tal oth Blank, Miri oth Pick, Chaim G. oth Shoenfeld, Yehuda oth Chapman, Joab oth Enthalten in Elsevier Science Li, Kuo ELSEVIER Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process 2020 official journal of the International Society for Neuroimmunology Amsterdam [u.a.] (DE-627)ELV005164184 volume:272 year:2014 number:1 day:15 month:07 pages:10-15 extent:6 https://doi.org/10.1016/j.jneuroim.2014.04.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 43.13 Umwelttoxikologie VZ 50.17 Sicherheitstechnik VZ 58.53 Abfallwirtschaft VZ AR 272 2014 1 15 0715 10-15 6 045F 610 |
allfieldsGer |
10.1016/j.jneuroim.2014.04.003 doi GBVA2014005000014.pica (DE-627)ELV017358752 (ELSEVIER)S0165-5728(14)00099-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 530 VZ 43.13 bkl 50.17 bkl 58.53 bkl Katzav, Aviva verfasserin aut Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. Ben-Ziv, Tal oth Blank, Miri oth Pick, Chaim G. oth Shoenfeld, Yehuda oth Chapman, Joab oth Enthalten in Elsevier Science Li, Kuo ELSEVIER Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process 2020 official journal of the International Society for Neuroimmunology Amsterdam [u.a.] (DE-627)ELV005164184 volume:272 year:2014 number:1 day:15 month:07 pages:10-15 extent:6 https://doi.org/10.1016/j.jneuroim.2014.04.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 43.13 Umwelttoxikologie VZ 50.17 Sicherheitstechnik VZ 58.53 Abfallwirtschaft VZ AR 272 2014 1 15 0715 10-15 6 045F 610 |
allfieldsSound |
10.1016/j.jneuroim.2014.04.003 doi GBVA2014005000014.pica (DE-627)ELV017358752 (ELSEVIER)S0165-5728(14)00099-X DE-627 ger DE-627 rakwb eng 610 610 DE-600 530 VZ 43.13 bkl 50.17 bkl 58.53 bkl Katzav, Aviva verfasserin aut Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. Ben-Ziv, Tal oth Blank, Miri oth Pick, Chaim G. oth Shoenfeld, Yehuda oth Chapman, Joab oth Enthalten in Elsevier Science Li, Kuo ELSEVIER Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process 2020 official journal of the International Society for Neuroimmunology Amsterdam [u.a.] (DE-627)ELV005164184 volume:272 year:2014 number:1 day:15 month:07 pages:10-15 extent:6 https://doi.org/10.1016/j.jneuroim.2014.04.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO 43.13 Umwelttoxikologie VZ 50.17 Sicherheitstechnik VZ 58.53 Abfallwirtschaft VZ AR 272 2014 1 15 0715 10-15 6 045F 610 |
language |
English |
source |
Enthalten in Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process Amsterdam [u.a.] volume:272 year:2014 number:1 day:15 month:07 pages:10-15 extent:6 |
sourceStr |
Enthalten in Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process Amsterdam [u.a.] volume:272 year:2014 number:1 day:15 month:07 pages:10-15 extent:6 |
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Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process |
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Katzav, Aviva @@aut@@ Ben-Ziv, Tal @@oth@@ Blank, Miri @@oth@@ Pick, Chaim G. @@oth@@ Shoenfeld, Yehuda @@oth@@ Chapman, Joab @@oth@@ |
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610 610 DE-600 530 VZ 43.13 bkl 50.17 bkl 58.53 bkl Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice |
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Decomposition of polycarbonate/acrylonitrile-butadiene-styrene blends in e-waste packaging resin and recovery of debrominated carbon materials by supercritical water oxidation process |
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Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice |
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Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice |
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antibody-specific behavioral effects: intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-p antibodies induces depression and smell deficits in mice |
title_auth |
Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice |
abstract |
This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. |
abstractGer |
This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. |
abstract_unstemmed |
This study compares the effects of human antiphospholipid (aPL) and anti-P-ribosomal (anti-P) IgG and control IgG on the brain. Intracerebroventricular (ICV) injected aPL mice (exAPS) displayed specific hyperactivity compared to anti-P-injected (exSLE) and control mice. In contrast ICV injected anti-P-injected mice specifically displayed depression-like behavior and olfactory impairment compared to the other 2 groups. Both anti-P and aPL injected mice were impaired in the passive avoidance test compared to controls. The distinct cognitive effects of the 2 pathogenic antibodies argue for a specific and differential direct action of these autoantibodies on the brain in clinical disease. |
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Antibody-specific behavioral effects: Intracerebroventricular injection of antiphospholipid antibodies induces hyperactive behavior while anti-ribosomal-P antibodies induces depression and smell deficits in mice |
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https://doi.org/10.1016/j.jneuroim.2014.04.003 |
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