Intra-amygdala microinfusion of IL-6 impairs the auditory fear conditioning of rats via JAK/STAT activation
• Intra-BLA infusion of IL-6 impaired the acquisition of auditory fear conditioning. • JAK/STAT was temporally activated–phosphorylated by the IL-6 treatment. • JSI-124, a JAK/STAT3 inhibitor, could reverse the IL-6 induced impairments.
Gespeichert in:
| Autor*in: |
Hao, Yongxin [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2014 |
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| Schlagwörter: |
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| Umfang: |
8 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Combined use of cisplatin plus natural killer cells overcomes immunoresistance of cisplatin resistant ovarian cancer - Choi, Seung Hee ELSEVIER, 2021, an international journal, Amsterdam |
|---|---|
| Übergeordnetes Werk: |
volume:275 ; year:2014 ; day:15 ; month:12 ; pages:88-95 ; extent:8 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.bbr.2014.08.052 |
|---|
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Intra-amygdala microinfusion of IL-6 impairs the auditory fear conditioning of rats via JAK/STAT activation |
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• Intra-BLA infusion of IL-6 impaired the acquisition of auditory fear conditioning. • JAK/STAT was temporally activated–phosphorylated by the IL-6 treatment. • JSI-124, a JAK/STAT3 inhibitor, could reverse the IL-6 induced impairments. |
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• Intra-BLA infusion of IL-6 impaired the acquisition of auditory fear conditioning. • JAK/STAT was temporally activated–phosphorylated by the IL-6 treatment. • JSI-124, a JAK/STAT3 inhibitor, could reverse the IL-6 induced impairments. |
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• Intra-BLA infusion of IL-6 impaired the acquisition of auditory fear conditioning. • JAK/STAT was temporally activated–phosphorylated by the IL-6 treatment. • JSI-124, a JAK/STAT3 inhibitor, could reverse the IL-6 induced impairments. |
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