Ultra-high-risk pregnancies in women after renal transplantation

Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who h...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Farr, Alex [verfasserIn] Bader, Yvonne [verfasserIn] Husslein, Peter W. [verfasserIn] Györi, Georg [verfasserIn] Mühlbacher, Ferdinand [verfasserIn] Margreiter, Markus [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome

Übergeordnetes Werk:	Enthalten in: European journal of obstetrics & gynecology and reproductive biology - Amsterdam [u.a.] : Elsevier Science, 1971, 180, Seite 72-76
Übergeordnetes Werk:	volume:180 ; pages:72-76

DOI / URN:	10.1016/j.ejogrb.2014.06.031

Katalog-ID:	ELV017458153

Internformat


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245	1	0	\|a Ultra-high-risk pregnancies in women after renal transplantation
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520			\|a Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who had undergone renal transplantation between 1999 and 2013 at our tertiary referral center and had subsequently become pregnant. Characteristics of pregnancy and perinatal outcome parameters; obstetrical, urological, and surgical risk factors; and graft function were assessed. Descriptive data analysis, Fisher's exact test, unpaired Student's t-test and one-way analysis of the variance were performed.Results: The overall pregnancy rate after renal transplantation was 5% (n =13). 77% of the patients (n =10) had ultra-high-risk pregnancies due to additional risk factors. These included twin pregnancy, placenta previa/percreta, hypertension; previous heart transplantation, previous myocardial infarction; postoperative lymphocele, urinary leakage, hydronephrosis, or vesico-ureteral reflux. Two patients had two consecutive pregnancies. A total of 12 deliveries with 13 newborns were achieved. Cesarean section and preterm delivery rates were 67% and 50%, respectively. Mean gestational week at delivery was 36±3. Mean creatinine levels were higher in women with preterm deliveries and in those of advanced age. Mean time between transplantation and delivery was 79±36 months. All patients had adequate graft function after a mean follow-up of 128±50 months after renal transplantation.Conclusions: Pregnant women after renal transplantation commonly present with additional risk factors. In these ultra-high-risk pregnancies successful outcomes can be achieved in a multidisciplinary setting. Adequate graft function and urinary tract evaluation is necessary.
650		4	\|a High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome
700	1		\|a Bader, Yvonne \|e verfasserin \|4 aut
700	1		\|a Husslein, Peter W. \|e verfasserin \|4 aut
700	1		\|a Györi, Georg \|e verfasserin \|4 aut
700	1		\|a Mühlbacher, Ferdinand \|e verfasserin \|0 (orcid)0000-0002-1884-2914 \|4 aut
700	1		\|a Margreiter, Markus \|e verfasserin \|4 aut
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publishDate	2014
allfields	10.1016/j.ejogrb.2014.06.031 doi (DE-627)ELV017458153 (ELSEVIER)S0301-2115(14)00360-1 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Farr, Alex verfasserin aut Ultra-high-risk pregnancies in women after renal transplantation 2014 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who had undergone renal transplantation between 1999 and 2013 at our tertiary referral center and had subsequently become pregnant. Characteristics of pregnancy and perinatal outcome parameters; obstetrical, urological, and surgical risk factors; and graft function were assessed. Descriptive data analysis, Fisher's exact test, unpaired Student's t-test and one-way analysis of the variance were performed.Results: The overall pregnancy rate after renal transplantation was 5% (n =13). 77% of the patients (n =10) had ultra-high-risk pregnancies due to additional risk factors. These included twin pregnancy, placenta previa/percreta, hypertension; previous heart transplantation, previous myocardial infarction; postoperative lymphocele, urinary leakage, hydronephrosis, or vesico-ureteral reflux. Two patients had two consecutive pregnancies. A total of 12 deliveries with 13 newborns were achieved. Cesarean section and preterm delivery rates were 67% and 50%, respectively. Mean gestational week at delivery was 36±3. Mean creatinine levels were higher in women with preterm deliveries and in those of advanced age. Mean time between transplantation and delivery was 79±36 months. All patients had adequate graft function after a mean follow-up of 128±50 months after renal transplantation.Conclusions: Pregnant women after renal transplantation commonly present with additional risk factors. In these ultra-high-risk pregnancies successful outcomes can be achieved in a multidisciplinary setting. Adequate graft function and urinary tract evaluation is necessary. High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome Bader, Yvonne verfasserin aut Husslein, Peter W. verfasserin aut Györi, Georg verfasserin aut Mühlbacher, Ferdinand verfasserin (orcid)0000-0002-1884-2914 aut Margreiter, Markus verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 180, Seite 72-76 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:180 pages:72-76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 180 72-76
spelling	10.1016/j.ejogrb.2014.06.031 doi (DE-627)ELV017458153 (ELSEVIER)S0301-2115(14)00360-1 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Farr, Alex verfasserin aut Ultra-high-risk pregnancies in women after renal transplantation 2014 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who had undergone renal transplantation between 1999 and 2013 at our tertiary referral center and had subsequently become pregnant. Characteristics of pregnancy and perinatal outcome parameters; obstetrical, urological, and surgical risk factors; and graft function were assessed. Descriptive data analysis, Fisher's exact test, unpaired Student's t-test and one-way analysis of the variance were performed.Results: The overall pregnancy rate after renal transplantation was 5% (n =13). 77% of the patients (n =10) had ultra-high-risk pregnancies due to additional risk factors. These included twin pregnancy, placenta previa/percreta, hypertension; previous heart transplantation, previous myocardial infarction; postoperative lymphocele, urinary leakage, hydronephrosis, or vesico-ureteral reflux. Two patients had two consecutive pregnancies. A total of 12 deliveries with 13 newborns were achieved. Cesarean section and preterm delivery rates were 67% and 50%, respectively. Mean gestational week at delivery was 36±3. Mean creatinine levels were higher in women with preterm deliveries and in those of advanced age. Mean time between transplantation and delivery was 79±36 months. All patients had adequate graft function after a mean follow-up of 128±50 months after renal transplantation.Conclusions: Pregnant women after renal transplantation commonly present with additional risk factors. In these ultra-high-risk pregnancies successful outcomes can be achieved in a multidisciplinary setting. Adequate graft function and urinary tract evaluation is necessary. High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome Bader, Yvonne verfasserin aut Husslein, Peter W. verfasserin aut Györi, Georg verfasserin aut Mühlbacher, Ferdinand verfasserin (orcid)0000-0002-1884-2914 aut Margreiter, Markus verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 180, Seite 72-76 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:180 pages:72-76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 180 72-76
allfields_unstemmed	10.1016/j.ejogrb.2014.06.031 doi (DE-627)ELV017458153 (ELSEVIER)S0301-2115(14)00360-1 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Farr, Alex verfasserin aut Ultra-high-risk pregnancies in women after renal transplantation 2014 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who had undergone renal transplantation between 1999 and 2013 at our tertiary referral center and had subsequently become pregnant. Characteristics of pregnancy and perinatal outcome parameters; obstetrical, urological, and surgical risk factors; and graft function were assessed. Descriptive data analysis, Fisher's exact test, unpaired Student's t-test and one-way analysis of the variance were performed.Results: The overall pregnancy rate after renal transplantation was 5% (n =13). 77% of the patients (n =10) had ultra-high-risk pregnancies due to additional risk factors. These included twin pregnancy, placenta previa/percreta, hypertension; previous heart transplantation, previous myocardial infarction; postoperative lymphocele, urinary leakage, hydronephrosis, or vesico-ureteral reflux. Two patients had two consecutive pregnancies. A total of 12 deliveries with 13 newborns were achieved. Cesarean section and preterm delivery rates were 67% and 50%, respectively. Mean gestational week at delivery was 36±3. Mean creatinine levels were higher in women with preterm deliveries and in those of advanced age. Mean time between transplantation and delivery was 79±36 months. All patients had adequate graft function after a mean follow-up of 128±50 months after renal transplantation.Conclusions: Pregnant women after renal transplantation commonly present with additional risk factors. In these ultra-high-risk pregnancies successful outcomes can be achieved in a multidisciplinary setting. Adequate graft function and urinary tract evaluation is necessary. High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome Bader, Yvonne verfasserin aut Husslein, Peter W. verfasserin aut Györi, Georg verfasserin aut Mühlbacher, Ferdinand verfasserin (orcid)0000-0002-1884-2914 aut Margreiter, Markus verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 180, Seite 72-76 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:180 pages:72-76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 180 72-76
allfieldsGer	10.1016/j.ejogrb.2014.06.031 doi (DE-627)ELV017458153 (ELSEVIER)S0301-2115(14)00360-1 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Farr, Alex verfasserin aut Ultra-high-risk pregnancies in women after renal transplantation 2014 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who had undergone renal transplantation between 1999 and 2013 at our tertiary referral center and had subsequently become pregnant. Characteristics of pregnancy and perinatal outcome parameters; obstetrical, urological, and surgical risk factors; and graft function were assessed. Descriptive data analysis, Fisher's exact test, unpaired Student's t-test and one-way analysis of the variance were performed.Results: The overall pregnancy rate after renal transplantation was 5% (n =13). 77% of the patients (n =10) had ultra-high-risk pregnancies due to additional risk factors. These included twin pregnancy, placenta previa/percreta, hypertension; previous heart transplantation, previous myocardial infarction; postoperative lymphocele, urinary leakage, hydronephrosis, or vesico-ureteral reflux. Two patients had two consecutive pregnancies. A total of 12 deliveries with 13 newborns were achieved. Cesarean section and preterm delivery rates were 67% and 50%, respectively. Mean gestational week at delivery was 36±3. Mean creatinine levels were higher in women with preterm deliveries and in those of advanced age. Mean time between transplantation and delivery was 79±36 months. All patients had adequate graft function after a mean follow-up of 128±50 months after renal transplantation.Conclusions: Pregnant women after renal transplantation commonly present with additional risk factors. In these ultra-high-risk pregnancies successful outcomes can be achieved in a multidisciplinary setting. Adequate graft function and urinary tract evaluation is necessary. High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome Bader, Yvonne verfasserin aut Husslein, Peter W. verfasserin aut Györi, Georg verfasserin aut Mühlbacher, Ferdinand verfasserin (orcid)0000-0002-1884-2914 aut Margreiter, Markus verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 180, Seite 72-76 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:180 pages:72-76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 180 72-76
allfieldsSound	10.1016/j.ejogrb.2014.06.031 doi (DE-627)ELV017458153 (ELSEVIER)S0301-2115(14)00360-1 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Farr, Alex verfasserin aut Ultra-high-risk pregnancies in women after renal transplantation 2014 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who had undergone renal transplantation between 1999 and 2013 at our tertiary referral center and had subsequently become pregnant. Characteristics of pregnancy and perinatal outcome parameters; obstetrical, urological, and surgical risk factors; and graft function were assessed. Descriptive data analysis, Fisher's exact test, unpaired Student's t-test and one-way analysis of the variance were performed.Results: The overall pregnancy rate after renal transplantation was 5% (n =13). 77% of the patients (n =10) had ultra-high-risk pregnancies due to additional risk factors. These included twin pregnancy, placenta previa/percreta, hypertension; previous heart transplantation, previous myocardial infarction; postoperative lymphocele, urinary leakage, hydronephrosis, or vesico-ureteral reflux. Two patients had two consecutive pregnancies. A total of 12 deliveries with 13 newborns were achieved. Cesarean section and preterm delivery rates were 67% and 50%, respectively. Mean gestational week at delivery was 36±3. Mean creatinine levels were higher in women with preterm deliveries and in those of advanced age. Mean time between transplantation and delivery was 79±36 months. All patients had adequate graft function after a mean follow-up of 128±50 months after renal transplantation.Conclusions: Pregnant women after renal transplantation commonly present with additional risk factors. In these ultra-high-risk pregnancies successful outcomes can be achieved in a multidisciplinary setting. Adequate graft function and urinary tract evaluation is necessary. High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome Bader, Yvonne verfasserin aut Husslein, Peter W. verfasserin aut Györi, Georg verfasserin aut Mühlbacher, Ferdinand verfasserin (orcid)0000-0002-1884-2914 aut Margreiter, Markus verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 180, Seite 72-76 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:180 pages:72-76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 180 72-76
language	English
source	Enthalten in European journal of obstetrics & gynecology and reproductive biology 180, Seite 72-76 volume:180 pages:72-76
sourceStr	Enthalten in European journal of obstetrics & gynecology and reproductive biology 180, Seite 72-76 volume:180 pages:72-76
format_phy_str_mv	Article
bklname	Gynäkologie
institution	findex.gbv.de
topic_facet	High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome
dewey-raw	610
isfreeaccess_bool	false
container_title	European journal of obstetrics & gynecology and reproductive biology
authorswithroles_txt_mv	Farr, Alex @@aut@@ Bader, Yvonne @@aut@@ Husslein, Peter W. @@aut@@ Györi, Georg @@aut@@ Mühlbacher, Ferdinand @@aut@@ Margreiter, Markus @@aut@@
publishDateDaySort_date	2014-01-01T00:00:00Z
hierarchy_top_id	320443469
dewey-sort	3610
id	ELV017458153
language_de	englisch
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author	Farr, Alex
spellingShingle	Farr, Alex ddc 610 bkl 44.92 misc High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome Ultra-high-risk pregnancies in women after renal transplantation
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topic_title	610 VZ 44.92 bkl Ultra-high-risk pregnancies in women after renal transplantation High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome
topic	ddc 610 bkl 44.92 misc High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome
topic_unstemmed	ddc 610 bkl 44.92 misc High-risk pregnancy, Pregnancy outcome, Renal transplantation, Transplant outcome
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title	Ultra-high-risk pregnancies in women after renal transplantation
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title_full	Ultra-high-risk pregnancies in women after renal transplantation
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author_browse	Farr, Alex Bader, Yvonne Husslein, Peter W. Györi, Georg Mühlbacher, Ferdinand Margreiter, Markus
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doi_str_mv	10.1016/j.ejogrb.2014.06.031
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title_sort	ultra-high-risk pregnancies in women after renal transplantation
title_auth	Ultra-high-risk pregnancies in women after renal transplantation
abstract	Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who had undergone renal transplantation between 1999 and 2013 at our tertiary referral center and had subsequently become pregnant. Characteristics of pregnancy and perinatal outcome parameters; obstetrical, urological, and surgical risk factors; and graft function were assessed. Descriptive data analysis, Fisher's exact test, unpaired Student's t-test and one-way analysis of the variance were performed.Results: The overall pregnancy rate after renal transplantation was 5% (n =13). 77% of the patients (n =10) had ultra-high-risk pregnancies due to additional risk factors. These included twin pregnancy, placenta previa/percreta, hypertension; previous heart transplantation, previous myocardial infarction; postoperative lymphocele, urinary leakage, hydronephrosis, or vesico-ureteral reflux. Two patients had two consecutive pregnancies. A total of 12 deliveries with 13 newborns were achieved. Cesarean section and preterm delivery rates were 67% and 50%, respectively. Mean gestational week at delivery was 36±3. Mean creatinine levels were higher in women with preterm deliveries and in those of advanced age. Mean time between transplantation and delivery was 79±36 months. All patients had adequate graft function after a mean follow-up of 128±50 months after renal transplantation.Conclusions: Pregnant women after renal transplantation commonly present with additional risk factors. In these ultra-high-risk pregnancies successful outcomes can be achieved in a multidisciplinary setting. Adequate graft function and urinary tract evaluation is necessary.
abstractGer	Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who had undergone renal transplantation between 1999 and 2013 at our tertiary referral center and had subsequently become pregnant. Characteristics of pregnancy and perinatal outcome parameters; obstetrical, urological, and surgical risk factors; and graft function were assessed. Descriptive data analysis, Fisher's exact test, unpaired Student's t-test and one-way analysis of the variance were performed.Results: The overall pregnancy rate after renal transplantation was 5% (n =13). 77% of the patients (n =10) had ultra-high-risk pregnancies due to additional risk factors. These included twin pregnancy, placenta previa/percreta, hypertension; previous heart transplantation, previous myocardial infarction; postoperative lymphocele, urinary leakage, hydronephrosis, or vesico-ureteral reflux. Two patients had two consecutive pregnancies. A total of 12 deliveries with 13 newborns were achieved. Cesarean section and preterm delivery rates were 67% and 50%, respectively. Mean gestational week at delivery was 36±3. Mean creatinine levels were higher in women with preterm deliveries and in those of advanced age. Mean time between transplantation and delivery was 79±36 months. All patients had adequate graft function after a mean follow-up of 128±50 months after renal transplantation.Conclusions: Pregnant women after renal transplantation commonly present with additional risk factors. In these ultra-high-risk pregnancies successful outcomes can be achieved in a multidisciplinary setting. Adequate graft function and urinary tract evaluation is necessary.
abstract_unstemmed	Objectives: This study evaluates pregnancy outcomes in renal transplant recipients who have additional obstetrical, surgical, or urological risk factors.Study design: Data from our transplantation and obstetrical databases were retrospectively analyzed to identify all women of reproductive age who had undergone renal transplantation between 1999 and 2013 at our tertiary referral center and had subsequently become pregnant. Characteristics of pregnancy and perinatal outcome parameters; obstetrical, urological, and surgical risk factors; and graft function were assessed. Descriptive data analysis, Fisher's exact test, unpaired Student's t-test and one-way analysis of the variance were performed.Results: The overall pregnancy rate after renal transplantation was 5% (n =13). 77% of the patients (n =10) had ultra-high-risk pregnancies due to additional risk factors. These included twin pregnancy, placenta previa/percreta, hypertension; previous heart transplantation, previous myocardial infarction; postoperative lymphocele, urinary leakage, hydronephrosis, or vesico-ureteral reflux. Two patients had two consecutive pregnancies. A total of 12 deliveries with 13 newborns were achieved. Cesarean section and preterm delivery rates were 67% and 50%, respectively. Mean gestational week at delivery was 36±3. Mean creatinine levels were higher in women with preterm deliveries and in those of advanced age. Mean time between transplantation and delivery was 79±36 months. All patients had adequate graft function after a mean follow-up of 128±50 months after renal transplantation.Conclusions: Pregnant women after renal transplantation commonly present with additional risk factors. In these ultra-high-risk pregnancies successful outcomes can be achieved in a multidisciplinary setting. Adequate graft function and urinary tract evaluation is necessary.
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title_short	Ultra-high-risk pregnancies in women after renal transplantation
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author2	Bader, Yvonne Husslein, Peter W. Györi, Georg Mühlbacher, Ferdinand Margreiter, Markus
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up_date	2024-07-06T22:02:16.651Z
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Ultra-high-risk pregnancies in women after renal transplantation

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