Detection of new psychoactive substance use among emergency room patients: Results from the Swedish STRIDA project
The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespr...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Helander, Anders [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014transfer abstract |
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| Schlagwörter: |
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| Umfang: |
7 |
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| Übergeordnetes Werk: |
Enthalten in: Cereal/grain legume intercropping in rotation with durum wheat in crop/livestock production systems for Mediterranean farming system - Monti, Michele ELSEVIER, 2019, an international journal dedicated to the applications of medicine and science in the administration of justice, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:243 ; year:2014 ; pages:23-29 ; extent:7 |
| Links: |
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| DOI / URN: |
10.1016/j.forsciint.2014.02.022 |
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| 520 | |a The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. | ||
| 520 | |a The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. | ||
| 650 | 7 | |a NPS |2 Elsevier | |
| 650 | 7 | |a Cannabinoids |2 Elsevier | |
| 650 | 7 | |a Cathinones |2 Elsevier | |
| 650 | 7 | |a Spice |2 Elsevier | |
| 650 | 7 | |a Substance use disorder/detection |2 Elsevier | |
| 650 | 7 | |a Phenethylamines |2 Elsevier | |
| 700 | 1 | |a Bäckberg, Matilda |4 oth | |
| 700 | 1 | |a Hultén, Peter |4 oth | |
| 700 | 1 | |a Al-Saffar, Yasir |4 oth | |
| 700 | 1 | |a Beck, Olof |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier Science |a Monti, Michele ELSEVIER |t Cereal/grain legume intercropping in rotation with durum wheat in crop/livestock production systems for Mediterranean farming system |d 2019 |d an international journal dedicated to the applications of medicine and science in the administration of justice |g Amsterdam [u.a.] |w (DE-627)ELV002577267 |
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10.1016/j.forsciint.2014.02.022 doi GBVA2014013000001.pica (DE-627)ELV017569168 (ELSEVIER)S0379-0738(14)00083-8 DE-627 ger DE-627 rakwb eng 340 610 340 DE-600 610 DE-600 630 640 VZ 48.00 bkl Helander, Anders verfasserin aut Detection of new psychoactive substance use among emergency room patients: Results from the Swedish STRIDA project 2014transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. NPS Elsevier Cannabinoids Elsevier Cathinones Elsevier Spice Elsevier Substance use disorder/detection Elsevier Phenethylamines Elsevier Bäckberg, Matilda oth Hultén, Peter oth Al-Saffar, Yasir oth Beck, Olof oth Enthalten in Elsevier Science Monti, Michele ELSEVIER Cereal/grain legume intercropping in rotation with durum wheat in crop/livestock production systems for Mediterranean farming system 2019 an international journal dedicated to the applications of medicine and science in the administration of justice Amsterdam [u.a.] (DE-627)ELV002577267 volume:243 year:2014 pages:23-29 extent:7 https://doi.org/10.1016/j.forsciint.2014.02.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 243 2014 23-29 7 045F 340 |
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10.1016/j.forsciint.2014.02.022 doi GBVA2014013000001.pica (DE-627)ELV017569168 (ELSEVIER)S0379-0738(14)00083-8 DE-627 ger DE-627 rakwb eng 340 610 340 DE-600 610 DE-600 630 640 VZ 48.00 bkl Helander, Anders verfasserin aut Detection of new psychoactive substance use among emergency room patients: Results from the Swedish STRIDA project 2014transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. NPS Elsevier Cannabinoids Elsevier Cathinones Elsevier Spice Elsevier Substance use disorder/detection Elsevier Phenethylamines Elsevier Bäckberg, Matilda oth Hultén, Peter oth Al-Saffar, Yasir oth Beck, Olof oth Enthalten in Elsevier Science Monti, Michele ELSEVIER Cereal/grain legume intercropping in rotation with durum wheat in crop/livestock production systems for Mediterranean farming system 2019 an international journal dedicated to the applications of medicine and science in the administration of justice Amsterdam [u.a.] (DE-627)ELV002577267 volume:243 year:2014 pages:23-29 extent:7 https://doi.org/10.1016/j.forsciint.2014.02.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 243 2014 23-29 7 045F 340 |
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10.1016/j.forsciint.2014.02.022 doi GBVA2014013000001.pica (DE-627)ELV017569168 (ELSEVIER)S0379-0738(14)00083-8 DE-627 ger DE-627 rakwb eng 340 610 340 DE-600 610 DE-600 630 640 VZ 48.00 bkl Helander, Anders verfasserin aut Detection of new psychoactive substance use among emergency room patients: Results from the Swedish STRIDA project 2014transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. NPS Elsevier Cannabinoids Elsevier Cathinones Elsevier Spice Elsevier Substance use disorder/detection Elsevier Phenethylamines Elsevier Bäckberg, Matilda oth Hultén, Peter oth Al-Saffar, Yasir oth Beck, Olof oth Enthalten in Elsevier Science Monti, Michele ELSEVIER Cereal/grain legume intercropping in rotation with durum wheat in crop/livestock production systems for Mediterranean farming system 2019 an international journal dedicated to the applications of medicine and science in the administration of justice Amsterdam [u.a.] (DE-627)ELV002577267 volume:243 year:2014 pages:23-29 extent:7 https://doi.org/10.1016/j.forsciint.2014.02.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 243 2014 23-29 7 045F 340 |
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10.1016/j.forsciint.2014.02.022 doi GBVA2014013000001.pica (DE-627)ELV017569168 (ELSEVIER)S0379-0738(14)00083-8 DE-627 ger DE-627 rakwb eng 340 610 340 DE-600 610 DE-600 630 640 VZ 48.00 bkl Helander, Anders verfasserin aut Detection of new psychoactive substance use among emergency room patients: Results from the Swedish STRIDA project 2014transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. NPS Elsevier Cannabinoids Elsevier Cathinones Elsevier Spice Elsevier Substance use disorder/detection Elsevier Phenethylamines Elsevier Bäckberg, Matilda oth Hultén, Peter oth Al-Saffar, Yasir oth Beck, Olof oth Enthalten in Elsevier Science Monti, Michele ELSEVIER Cereal/grain legume intercropping in rotation with durum wheat in crop/livestock production systems for Mediterranean farming system 2019 an international journal dedicated to the applications of medicine and science in the administration of justice Amsterdam [u.a.] (DE-627)ELV002577267 volume:243 year:2014 pages:23-29 extent:7 https://doi.org/10.1016/j.forsciint.2014.02.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 243 2014 23-29 7 045F 340 |
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10.1016/j.forsciint.2014.02.022 doi GBVA2014013000001.pica (DE-627)ELV017569168 (ELSEVIER)S0379-0738(14)00083-8 DE-627 ger DE-627 rakwb eng 340 610 340 DE-600 610 DE-600 630 640 VZ 48.00 bkl Helander, Anders verfasserin aut Detection of new psychoactive substance use among emergency room patients: Results from the Swedish STRIDA project 2014transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. NPS Elsevier Cannabinoids Elsevier Cathinones Elsevier Spice Elsevier Substance use disorder/detection Elsevier Phenethylamines Elsevier Bäckberg, Matilda oth Hultén, Peter oth Al-Saffar, Yasir oth Beck, Olof oth Enthalten in Elsevier Science Monti, Michele ELSEVIER Cereal/grain legume intercropping in rotation with durum wheat in crop/livestock production systems for Mediterranean farming system 2019 an international journal dedicated to the applications of medicine and science in the administration of justice Amsterdam [u.a.] (DE-627)ELV002577267 volume:243 year:2014 pages:23-29 extent:7 https://doi.org/10.1016/j.forsciint.2014.02.022 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 243 2014 23-29 7 045F 340 |
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Enthalten in Cereal/grain legume intercropping in rotation with durum wheat in crop/livestock production systems for Mediterranean farming system Amsterdam [u.a.] volume:243 year:2014 pages:23-29 extent:7 |
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Detection of new psychoactive substance use among emergency room patients: Results from the Swedish STRIDA project |
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The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. |
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The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. |
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The “STRIDA” project monitors the occurrence and trends of new psychoactive substances (NPS; “Internet drugs/designer drugs/legal highs”) in Sweden, and collects information about their clinical symptoms, toxicity and associated health hazards. The initial results of the project documented a widespread use of many different NPS by mainly adolescents and young (age range 13–63 years, median 20), male (79%) adults, among cases of drug intoxications presenting at emergency departments and intensive care units across the country. The new substances were identified in samples of urine and blood by a multi-component LC–MS/MS method, and the severity of clinical symptoms were graded by the Poisoning Severity Score (PSS). Of the initial 189 samples submitted for laboratory investigation, 156 (83%) tested positive for at least one drug. Besides classical substances such as ethanol, cannabis and amphetamines, many NPS were detected comprising synthetic cannabinoid receptor agonists (“Spice”), piperazines, substituted phenethylamines, synthetic cathinones, hallucinogenic tryptamines, piperidines, opioid related substances, ketamine and related substances, and GABA analogues (in total more than 50 substances). About half of the cases were demonstrated to be multiple drug intoxications, sometimes making it hard to associate the clinical presentations with one specific substance. In conclusion, the STRIDA project has documented use of a broad variety of NPS among mainly young people all over Sweden. |
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