Conserved regions of the DMD 3′ UTR regulate translation and mRNA abundance in cultured myotubes
• The effects of the DMD UTRs on dystrophin expression were examined in C2C12 cells. • DMD 5′ UTRs initiate translation with low efficiency in C2C12 cells. • The DMD 3′ UTR contains highly conserved elements (HCEs). • The DMD 3′ UTR HCEs increase mRNA levels and translation during differentiation....
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Larsen, C. Aaron [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2014 |
|---|
| Schlagwörter: |
|---|
| Umfang: |
14 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Sperm competition in golden cuttlefish - Guo, Haoyu ELSEVIER, 2020, official journal of the World Muscle Society, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:24 ; year:2014 ; number:8 ; pages:693-706 ; extent:14 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.nmd.2014.05.006 |
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ELV017757487 |
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• The effects of the DMD UTRs on dystrophin expression were examined in C2C12 cells. • DMD 5′ UTRs initiate translation with low efficiency in C2C12 cells. • The DMD 3′ UTR contains highly conserved elements (HCEs). • The DMD 3′ UTR HCEs increase mRNA levels and translation during differentiation. |
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• The effects of the DMD UTRs on dystrophin expression were examined in C2C12 cells. • DMD 5′ UTRs initiate translation with low efficiency in C2C12 cells. • The DMD 3′ UTR contains highly conserved elements (HCEs). • The DMD 3′ UTR HCEs increase mRNA levels and translation during differentiation. |
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• The effects of the DMD UTRs on dystrophin expression were examined in C2C12 cells. • DMD 5′ UTRs initiate translation with low efficiency in C2C12 cells. • The DMD 3′ UTR contains highly conserved elements (HCEs). • The DMD 3′ UTR HCEs increase mRNA levels and translation during differentiation. |
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