TALE nickase mediates high efficient targeted transgene integration at the human multi-copy ribosomal DNA locus
• TALENickases were described for the first time. • TALENickases stimulated targeted gene addition remarkably. • TALENickases were even more effective than TALENs at the rDNA locus.
Gespeichert in:
| Autor*in: |
Wu, Yong [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014 |
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| Schlagwörter: |
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| Umfang: |
6 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Preparation and characterization of glass-ceramics via co-sintering of coal fly ash and oil shale ash-derived amorphous slag - Zhang, Zhikun ELSEVIER, 2019, BBRC, Orlando, Fla |
|---|---|
| Übergeordnetes Werk: |
volume:446 ; year:2014 ; number:1 ; day:28 ; month:03 ; pages:261-266 ; extent:6 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.bbrc.2014.02.099 |
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TALE nickase mediates high efficient targeted transgene integration at the human multi-copy ribosomal DNA locus |
| abstract |
• TALENickases were described for the first time. • TALENickases stimulated targeted gene addition remarkably. • TALENickases were even more effective than TALENs at the rDNA locus. |
| abstractGer |
• TALENickases were described for the first time. • TALENickases stimulated targeted gene addition remarkably. • TALENickases were even more effective than TALENs at the rDNA locus. |
| abstract_unstemmed |
• TALENickases were described for the first time. • TALENickases stimulated targeted gene addition remarkably. • TALENickases were even more effective than TALENs at the rDNA locus. |
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| title_short |
TALE nickase mediates high efficient targeted transgene integration at the human multi-copy ribosomal DNA locus |
| url |
https://doi.org/10.1016/j.bbrc.2014.02.099 |
| remote_bool |
true |
| author2 |
Gao, Tieli Wang, Xiaolin Hu, Youjin Hu, Xuyun Hu, Zhiqing Pang, Jialun Li, Zhuo Xue, Jinfeng Feng, Mai Wu, Lingqian Liang, Desheng |
| author2Str |
Gao, Tieli Wang, Xiaolin Hu, Youjin Hu, Xuyun Hu, Zhiqing Pang, Jialun Li, Zhuo Xue, Jinfeng Feng, Mai Wu, Lingqian Liang, Desheng |
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ELV002811154 |
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| doi_str |
10.1016/j.bbrc.2014.02.099 |
| up_date |
2024-07-06T17:35:11.884Z |
| _version_ |
1803851988348174336 |
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7.39979 |