Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children
Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neithe...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Chandrakasan, Shanmuganathan [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014transfer abstract |
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| Schlagwörter: |
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| Umfang: |
3 |
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| Übergeordnetes Werk: |
Enthalten in: Media usage diminishes memory for experiences - Tamir, Diana I. ELSEVIER, 2018, St. Louis, Mo |
|---|---|
| Übergeordnetes Werk: |
volume:164 ; year:2014 ; number:4 ; pages:928-930 ; extent:3 |
| Links: |
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| DOI / URN: |
10.1016/j.jpeds.2013.11.026 |
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| 520 | |a Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. | ||
| 520 | |a Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. | ||
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10.1016/j.jpeds.2013.11.026 doi GBVA2014022000005.pica (DE-627)ELV018023657 (ELSEVIER)S0022-3476(13)01461-3 DE-627 ger DE-627 rakwb eng 610 610 DE-600 150 VZ LING DE-30 fid 77.00 bkl Chandrakasan, Shanmuganathan verfasserin aut Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children 2014transfer abstract 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. CRP Elsevier CT Elsevier PCV Elsevier IL Elsevier ESR Elsevier SUV Elsevier AI Elsevier sTfR Elsevier PET Elsevier Bakeer, Nihal oth Mo, Jun Qin oth Cost, Carrye oth Quinn, Charles T. oth Enthalten in Mosby Tamir, Diana I. ELSEVIER Media usage diminishes memory for experiences 2018 St. Louis, Mo (DE-627)ELV001345303 volume:164 year:2014 number:4 pages:928-930 extent:3 https://doi.org/10.1016/j.jpeds.2013.11.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING 77.00 Psychologie: Allgemeines VZ AR 164 2014 4 928-930 3 045F 610 |
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10.1016/j.jpeds.2013.11.026 doi GBVA2014022000005.pica (DE-627)ELV018023657 (ELSEVIER)S0022-3476(13)01461-3 DE-627 ger DE-627 rakwb eng 610 610 DE-600 150 VZ LING DE-30 fid 77.00 bkl Chandrakasan, Shanmuganathan verfasserin aut Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children 2014transfer abstract 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. CRP Elsevier CT Elsevier PCV Elsevier IL Elsevier ESR Elsevier SUV Elsevier AI Elsevier sTfR Elsevier PET Elsevier Bakeer, Nihal oth Mo, Jun Qin oth Cost, Carrye oth Quinn, Charles T. oth Enthalten in Mosby Tamir, Diana I. ELSEVIER Media usage diminishes memory for experiences 2018 St. Louis, Mo (DE-627)ELV001345303 volume:164 year:2014 number:4 pages:928-930 extent:3 https://doi.org/10.1016/j.jpeds.2013.11.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING 77.00 Psychologie: Allgemeines VZ AR 164 2014 4 928-930 3 045F 610 |
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10.1016/j.jpeds.2013.11.026 doi GBVA2014022000005.pica (DE-627)ELV018023657 (ELSEVIER)S0022-3476(13)01461-3 DE-627 ger DE-627 rakwb eng 610 610 DE-600 150 VZ LING DE-30 fid 77.00 bkl Chandrakasan, Shanmuganathan verfasserin aut Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children 2014transfer abstract 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. CRP Elsevier CT Elsevier PCV Elsevier IL Elsevier ESR Elsevier SUV Elsevier AI Elsevier sTfR Elsevier PET Elsevier Bakeer, Nihal oth Mo, Jun Qin oth Cost, Carrye oth Quinn, Charles T. oth Enthalten in Mosby Tamir, Diana I. ELSEVIER Media usage diminishes memory for experiences 2018 St. Louis, Mo (DE-627)ELV001345303 volume:164 year:2014 number:4 pages:928-930 extent:3 https://doi.org/10.1016/j.jpeds.2013.11.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING 77.00 Psychologie: Allgemeines VZ AR 164 2014 4 928-930 3 045F 610 |
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10.1016/j.jpeds.2013.11.026 doi GBVA2014022000005.pica (DE-627)ELV018023657 (ELSEVIER)S0022-3476(13)01461-3 DE-627 ger DE-627 rakwb eng 610 610 DE-600 150 VZ LING DE-30 fid 77.00 bkl Chandrakasan, Shanmuganathan verfasserin aut Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children 2014transfer abstract 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. CRP Elsevier CT Elsevier PCV Elsevier IL Elsevier ESR Elsevier SUV Elsevier AI Elsevier sTfR Elsevier PET Elsevier Bakeer, Nihal oth Mo, Jun Qin oth Cost, Carrye oth Quinn, Charles T. oth Enthalten in Mosby Tamir, Diana I. ELSEVIER Media usage diminishes memory for experiences 2018 St. Louis, Mo (DE-627)ELV001345303 volume:164 year:2014 number:4 pages:928-930 extent:3 https://doi.org/10.1016/j.jpeds.2013.11.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING 77.00 Psychologie: Allgemeines VZ AR 164 2014 4 928-930 3 045F 610 |
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Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children |
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Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children |
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Chandrakasan, Shanmuganathan |
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iron-refractory microcytic anemia as the presenting feature of unicentric castleman disease in children |
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Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children |
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Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. |
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Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. |
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Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. Diagnosis was delayed because neither child had palpable lymphadenopathy and the lymphoproliferation was intra-abdominal. Surgical resection cured the anemia and the Castleman disease. A diagnostic clue to Castleman disease is an elevated concentration of interleukin-6 in blood, which causes anemia by inducing the expression of the iron-regulatory hormone hepcidin. |
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Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children |
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