Solubility of anti-inflammatory drug lornoxicam in ten different green solvents at different temperatures
In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-et...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Shakeel, Faiyaz [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015transfer abstract |
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| Umfang: |
4 |
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| Übergeordnetes Werk: |
Enthalten in: Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects - Moreno-Cabezali, Belen Maria ELSEVIER, 2020, an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids, New York, NY [u.a.] |
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| Übergeordnetes Werk: |
volume:209 ; year:2015 ; pages:280-283 ; extent:4 |
| Links: |
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| DOI / URN: |
10.1016/j.molliq.2015.05.035 |
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| 520 | |a In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. | ||
| 520 | |a In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. | ||
| 700 | 1 | |a Haq, Nazrul |4 oth | |
| 700 | 1 | |a Alanazi, Fars K. |4 oth | |
| 700 | 1 | |a Alsarra, Ibrahim A. |4 oth | |
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10.1016/j.molliq.2015.05.035 doi GBVA2015004000025.pica (DE-627)ELV018261825 (ELSEVIER)S0167-7322(15)30108-2 DE-627 ger DE-627 rakwb eng 540 540 DE-600 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility of anti-inflammatory drug lornoxicam in ten different green solvents at different temperatures 2015transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:209 year:2015 pages:280-283 extent:4 https://doi.org/10.1016/j.molliq.2015.05.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 209 2015 280-283 4 045F 540 |
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10.1016/j.molliq.2015.05.035 doi GBVA2015004000025.pica (DE-627)ELV018261825 (ELSEVIER)S0167-7322(15)30108-2 DE-627 ger DE-627 rakwb eng 540 540 DE-600 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility of anti-inflammatory drug lornoxicam in ten different green solvents at different temperatures 2015transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:209 year:2015 pages:280-283 extent:4 https://doi.org/10.1016/j.molliq.2015.05.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 209 2015 280-283 4 045F 540 |
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10.1016/j.molliq.2015.05.035 doi GBVA2015004000025.pica (DE-627)ELV018261825 (ELSEVIER)S0167-7322(15)30108-2 DE-627 ger DE-627 rakwb eng 540 540 DE-600 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility of anti-inflammatory drug lornoxicam in ten different green solvents at different temperatures 2015transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:209 year:2015 pages:280-283 extent:4 https://doi.org/10.1016/j.molliq.2015.05.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 209 2015 280-283 4 045F 540 |
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10.1016/j.molliq.2015.05.035 doi GBVA2015004000025.pica (DE-627)ELV018261825 (ELSEVIER)S0167-7322(15)30108-2 DE-627 ger DE-627 rakwb eng 540 540 DE-600 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility of anti-inflammatory drug lornoxicam in ten different green solvents at different temperatures 2015transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:209 year:2015 pages:280-283 extent:4 https://doi.org/10.1016/j.molliq.2015.05.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 209 2015 280-283 4 045F 540 |
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10.1016/j.molliq.2015.05.035 doi GBVA2015004000025.pica (DE-627)ELV018261825 (ELSEVIER)S0167-7322(15)30108-2 DE-627 ger DE-627 rakwb eng 540 540 DE-600 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility of anti-inflammatory drug lornoxicam in ten different green solvents at different temperatures 2015transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:209 year:2015 pages:280-283 extent:4 https://doi.org/10.1016/j.molliq.2015.05.035 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 209 2015 280-283 4 045F 540 |
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Enthalten in Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects New York, NY [u.a.] volume:209 year:2015 pages:280-283 extent:4 |
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The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. 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solubility of anti-inflammatory drug lornoxicam in ten different green solvents at different temperatures |
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Solubility of anti-inflammatory drug lornoxicam in ten different green solvents at different temperatures |
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In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. |
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In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. |
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In this work, the solubility of poorly water soluble anti-inflammatory drug lornoxicam (LOX) in ten different green solvents such as water, ethanol, 1-butanol, 2-butanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG), polyethylene glycol-400 (PEG-400) and 2-(2-ethoxyethoxy) ethanol was measured at T =(298.15 to 323.15) K and p =0.1MPa using an isothermal method. The measured solubility data of LOX were correlated with Apelblat and Van't Hoff models with root mean square deviations in the range of 0.33 to 3.70%. The mole fraction solubility of LOX was observed highest in PEG-400 (8.55×10−3) followed by 2-(2-ethoxyethoxy) ethanol, EG, EA, PG, 2-butanol, 1-butanol, IPA, ethanol and water at T =298.15K. Thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of LOX in all green solvents. |
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