Danger signals in stroke
Danger molecules are the first signals released from dying tissue after stroke. These danger signals bind to receptors on immune cells that will result in their activation and the release of inflammatory and neurotoxic mediators, resulting in amplification of the immune response and subsequent enlar...
Ausführliche Beschreibung
Autor*in: |
Gelderblom, Mathias [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2015 |
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Schlagwörter: |
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Umfang: |
6 |
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Übergeordnetes Werk: |
Enthalten in: Hierarchical nanoassembly of Ni/MoS - Fu, Zhuai ELSEVIER, 2022, ARR, Oxford [u.a.] |
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Übergeordnetes Werk: |
volume:24 ; year:2015 ; pages:77-82 ; extent:6 |
Links: |
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DOI / URN: |
10.1016/j.arr.2015.07.004 |
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10.1016/j.arr.2015.07.004 doi GBVA2015007000003.pica (DE-627)ELV018350917 (ELSEVIER)S1568-1637(15)30006-4 DE-627 ger DE-627 rakwb eng 610 610 DE-600 540 VZ 35.00 bkl Gelderblom, Mathias verfasserin aut Danger signals in stroke 2015 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Danger molecules are the first signals released from dying tissue after stroke. These danger signals bind to receptors on immune cells that will result in their activation and the release of inflammatory and neurotoxic mediators, resulting in amplification of the immune response and subsequent enlargement of the damaged brain volume. The release of danger signals is a central event that leads to a multitude of signals and cascades in the affected and neighbouring tissue, therefore providing a potential target for therapy. Stroke Elsevier Hsp Elsevier Inflammation Elsevier HMGB1 Elsevier DAMP Elsevier Sobey, Christopher G. oth Kleinschnitz, Christoph oth Magnus, Tim oth Enthalten in Elsevier Fu, Zhuai ELSEVIER Hierarchical nanoassembly of Ni/MoS 2022 ARR Oxford [u.a.] (DE-627)ELV007865341 volume:24 year:2015 pages:77-82 extent:6 https://doi.org/10.1016/j.arr.2015.07.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.00 Chemie: Allgemeines VZ AR 24 2015 77-82 6 045F 610 |
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10.1016/j.arr.2015.07.004 doi GBVA2015007000003.pica (DE-627)ELV018350917 (ELSEVIER)S1568-1637(15)30006-4 DE-627 ger DE-627 rakwb eng 610 610 DE-600 540 VZ 35.00 bkl Gelderblom, Mathias verfasserin aut Danger signals in stroke 2015 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Danger molecules are the first signals released from dying tissue after stroke. These danger signals bind to receptors on immune cells that will result in their activation and the release of inflammatory and neurotoxic mediators, resulting in amplification of the immune response and subsequent enlargement of the damaged brain volume. The release of danger signals is a central event that leads to a multitude of signals and cascades in the affected and neighbouring tissue, therefore providing a potential target for therapy. Stroke Elsevier Hsp Elsevier Inflammation Elsevier HMGB1 Elsevier DAMP Elsevier Sobey, Christopher G. oth Kleinschnitz, Christoph oth Magnus, Tim oth Enthalten in Elsevier Fu, Zhuai ELSEVIER Hierarchical nanoassembly of Ni/MoS 2022 ARR Oxford [u.a.] (DE-627)ELV007865341 volume:24 year:2015 pages:77-82 extent:6 https://doi.org/10.1016/j.arr.2015.07.004 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.00 Chemie: Allgemeines VZ AR 24 2015 77-82 6 045F 610 |
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Danger molecules are the first signals released from dying tissue after stroke. These danger signals bind to receptors on immune cells that will result in their activation and the release of inflammatory and neurotoxic mediators, resulting in amplification of the immune response and subsequent enlargement of the damaged brain volume. The release of danger signals is a central event that leads to a multitude of signals and cascades in the affected and neighbouring tissue, therefore providing a potential target for therapy. |
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Danger molecules are the first signals released from dying tissue after stroke. These danger signals bind to receptors on immune cells that will result in their activation and the release of inflammatory and neurotoxic mediators, resulting in amplification of the immune response and subsequent enlargement of the damaged brain volume. The release of danger signals is a central event that leads to a multitude of signals and cascades in the affected and neighbouring tissue, therefore providing a potential target for therapy. |
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Danger molecules are the first signals released from dying tissue after stroke. These danger signals bind to receptors on immune cells that will result in their activation and the release of inflammatory and neurotoxic mediators, resulting in amplification of the immune response and subsequent enlargement of the damaged brain volume. The release of danger signals is a central event that leads to a multitude of signals and cascades in the affected and neighbouring tissue, therefore providing a potential target for therapy. |
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