Involvement of dopaminergic and cholinergic systems in social isolation-induced deficits in social affiliation and conditional fear memory in mice
• Social isolation (SI) from early weaning impaired social affiliation (SA) and fear memory in mice. • Methylphenidate improved SA deficit via dopamine (DA) D1 receptors. • Tacrine (THA) improved fear memory deficit via muscarinic receptors. • The effect of THA was mediated by hippocampal neuro-sign...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Okada, R. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Umfang: |
12 |
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| Übergeordnetes Werk: |
Enthalten in: Status of beetroot processing and processed products: Thermal and emerging technologies intervention - Dhiman, Atul ELSEVIER, 2021, an international journal under the editorial direction of IBRO, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:299 ; year:2015 ; day:23 ; month:07 ; pages:134-145 ; extent:12 |
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| DOI / URN: |
10.1016/j.neuroscience.2015.04.064 |
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involvement of dopaminergic and cholinergic systems in social isolation-induced deficits in social affiliation and conditional fear memory in mice |
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Involvement of dopaminergic and cholinergic systems in social isolation-induced deficits in social affiliation and conditional fear memory in mice |
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• Social isolation (SI) from early weaning impaired social affiliation (SA) and fear memory in mice. • Methylphenidate improved SA deficit via dopamine (DA) D1 receptors. • Tacrine (THA) improved fear memory deficit via muscarinic receptors. • The effect of THA was mediated by hippocampal neuro-signaling and Egr-1 systems. • SI impairs SA and fear memory via DA and cholinergic systems, respectively. |
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• Social isolation (SI) from early weaning impaired social affiliation (SA) and fear memory in mice. • Methylphenidate improved SA deficit via dopamine (DA) D1 receptors. • Tacrine (THA) improved fear memory deficit via muscarinic receptors. • The effect of THA was mediated by hippocampal neuro-signaling and Egr-1 systems. • SI impairs SA and fear memory via DA and cholinergic systems, respectively. |
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• Social isolation (SI) from early weaning impaired social affiliation (SA) and fear memory in mice. • Methylphenidate improved SA deficit via dopamine (DA) D1 receptors. • Tacrine (THA) improved fear memory deficit via muscarinic receptors. • The effect of THA was mediated by hippocampal neuro-signaling and Egr-1 systems. • SI impairs SA and fear memory via DA and cholinergic systems, respectively. |
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Involvement of dopaminergic and cholinergic systems in social isolation-induced deficits in social affiliation and conditional fear memory in mice |
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2024-07-06T18:45:22.124Z |
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