The brain mineralocorticoid receptor and stress resilience
• The brain MR is an important stress modulator and influences stress appraisal. • The brain MR influences basal and stress-induced HPA-axis activity. • Cortisol effects on the MR appear to be at least partially sex-dependent. • Lower MR functionality may result in an increased susceptibility for st...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
ter Heegde, Freija [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Umfang: |
19 |
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| Übergeordnetes Werk: |
Enthalten in: Crystal structure details of - Wang, Weiwei ELSEVIER, 2021, an international journal : the official journal of the International Society of Psychoneuroendocrinology, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:52 ; year:2015 ; pages:92-110 ; extent:19 |
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| DOI / URN: |
10.1016/j.psyneuen.2014.10.022 |
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| 520 | |a • The brain MR is an important stress modulator and influences stress appraisal. • The brain MR influences basal and stress-induced HPA-axis activity. • Cortisol effects on the MR appear to be at least partially sex-dependent. • Lower MR functionality may result in an increased susceptibility for stress. • Increasing activity or expression of brain MRs may prevent or reverse depression. | ||
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• The brain MR is an important stress modulator and influences stress appraisal. • The brain MR influences basal and stress-induced HPA-axis activity. • Cortisol effects on the MR appear to be at least partially sex-dependent. • Lower MR functionality may result in an increased susceptibility for stress. • Increasing activity or expression of brain MRs may prevent or reverse depression. |
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