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The outcomes of many diseases differ between women and men, with women having a higher incidence and more severe pathogenesis of autoimmune and some infectious diseases, including influenza and HIV-1. In HIV-1 infection, clinical studies have shown faster disease progression and stronger immune acti...
Ausführliche Beschreibung
Autor*in: |
Ziegler, Susanne M. [verfasserIn] |
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Sprache: |
Englisch |
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2015transfer abstract |
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Enthalten in: The minimal clinically important differences of the Simple Shoulder Test are different for different arthroplasty types - McLaughlin, Richard J. ELSEVIER, 2022, the official journal of the International Cytokine Society, Oxford [u.a.] |
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Übergeordnetes Werk: |
volume:76 ; year:2015 ; number:1 ; pages:92 |
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10.1016/j.cyto.2015.08.168 |
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The outcomes of many diseases differ between women and men, with women having a higher incidence and more severe pathogenesis of autoimmune and some infectious diseases, including influenza and HIV-1. In HIV-1 infection, clinical studies have shown faster disease progression and stronger immune activation in females compared to males for the same level of viral replication, as well as better control of initial viremia in women during primary infection (Meier, 2009; Sterling, 2001; Farzadegan, 1998). It has been suggested that this is partially due to TLR-mediated activation of pDC, the main producers of IFN- α , in response to HIV-1 ssRNA. |
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The outcomes of many diseases differ between women and men, with women having a higher incidence and more severe pathogenesis of autoimmune and some infectious diseases, including influenza and HIV-1. In HIV-1 infection, clinical studies have shown faster disease progression and stronger immune activation in females compared to males for the same level of viral replication, as well as better control of initial viremia in women during primary infection (Meier, 2009; Sterling, 2001; Farzadegan, 1998). It has been suggested that this is partially due to TLR-mediated activation of pDC, the main producers of IFN- α , in response to HIV-1 ssRNA. |
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The outcomes of many diseases differ between women and men, with women having a higher incidence and more severe pathogenesis of autoimmune and some infectious diseases, including influenza and HIV-1. In HIV-1 infection, clinical studies have shown faster disease progression and stronger immune activation in females compared to males for the same level of viral replication, as well as better control of initial viremia in women during primary infection (Meier, 2009; Sterling, 2001; Farzadegan, 1998). It has been suggested that this is partially due to TLR-mediated activation of pDC, the main producers of IFN- α , in response to HIV-1 ssRNA. |
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