Solubility and thermodynamic function of lornoxicam in (PEG-400+water) mixtures at different temperatures
The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilit...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Shakeel, Faiyaz [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016transfer abstract |
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| Umfang: |
5 |
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| Übergeordnetes Werk: |
Enthalten in: Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects - Moreno-Cabezali, Belen Maria ELSEVIER, 2020, an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids, New York, NY [u.a.] |
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| Übergeordnetes Werk: |
volume:219 ; year:2016 ; pages:439-443 ; extent:5 |
| Links: |
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| DOI / URN: |
10.1016/j.molliq.2016.03.058 |
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| 245 | 1 | 0 | |a Solubility and thermodynamic function of lornoxicam in (PEG-400+water) mixtures at different temperatures |
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| 520 | |a The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. | ||
| 520 | |a The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. | ||
| 700 | 1 | |a Haq, Nazrul |4 oth | |
| 700 | 1 | |a Alanazi, Fars K. |4 oth | |
| 700 | 1 | |a Alsarra, Ibrahim A. |4 oth | |
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10.1016/j.molliq.2016.03.058 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000846.pica (DE-627)ELV019110553 (ELSEVIER)S0167-7322(16)30471-8 DE-627 ger DE-627 rakwb eng 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility and thermodynamic function of lornoxicam in (PEG-400+water) mixtures at different temperatures 2016transfer abstract 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:219 year:2016 pages:439-443 extent:5 https://doi.org/10.1016/j.molliq.2016.03.058 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 219 2016 439-443 5 |
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10.1016/j.molliq.2016.03.058 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000846.pica (DE-627)ELV019110553 (ELSEVIER)S0167-7322(16)30471-8 DE-627 ger DE-627 rakwb eng 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility and thermodynamic function of lornoxicam in (PEG-400+water) mixtures at different temperatures 2016transfer abstract 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:219 year:2016 pages:439-443 extent:5 https://doi.org/10.1016/j.molliq.2016.03.058 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 219 2016 439-443 5 |
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10.1016/j.molliq.2016.03.058 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000846.pica (DE-627)ELV019110553 (ELSEVIER)S0167-7322(16)30471-8 DE-627 ger DE-627 rakwb eng 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility and thermodynamic function of lornoxicam in (PEG-400+water) mixtures at different temperatures 2016transfer abstract 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:219 year:2016 pages:439-443 extent:5 https://doi.org/10.1016/j.molliq.2016.03.058 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 219 2016 439-443 5 |
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10.1016/j.molliq.2016.03.058 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000846.pica (DE-627)ELV019110553 (ELSEVIER)S0167-7322(16)30471-8 DE-627 ger DE-627 rakwb eng 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility and thermodynamic function of lornoxicam in (PEG-400+water) mixtures at different temperatures 2016transfer abstract 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:219 year:2016 pages:439-443 extent:5 https://doi.org/10.1016/j.molliq.2016.03.058 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 219 2016 439-443 5 |
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10.1016/j.molliq.2016.03.058 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000846.pica (DE-627)ELV019110553 (ELSEVIER)S0167-7322(16)30471-8 DE-627 ger DE-627 rakwb eng 004 VZ 85.35 bkl 54.80 bkl Shakeel, Faiyaz verfasserin aut Solubility and thermodynamic function of lornoxicam in (PEG-400+water) mixtures at different temperatures 2016transfer abstract 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. Haq, Nazrul oth Alanazi, Fars K. oth Alsarra, Ibrahim A. oth Enthalten in Elsevier Moreno-Cabezali, Belen Maria ELSEVIER Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects 2020 an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids New York, NY [u.a.] (DE-627)ELV004280490 volume:219 year:2016 pages:439-443 extent:5 https://doi.org/10.1016/j.molliq.2016.03.058 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 85.35 Fertigung VZ 54.80 Angewandte Informatik VZ AR 219 2016 439-443 5 |
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Enthalten in Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects New York, NY [u.a.] volume:219 year:2016 pages:439-443 extent:5 |
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The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. 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solubility and thermodynamic function of lornoxicam in (peg-400+water) mixtures at different temperatures |
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Solubility and thermodynamic function of lornoxicam in (PEG-400+water) mixtures at different temperatures |
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The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. |
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The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. |
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The present study was undertaken to determine the solubility and thermodynamic function of a poorly soluble drug lornoxicam (LNX) in various [polyethylene glycol-400 (PEG-400)+water] mixtures at five different temperatures from T =(298.15 to 323.15) K and atmospheric pressure. The measured solubilities of LNX were correlated with three different mathematical models which showed good correlation of experimental solubilities of LNX with calculated ones. The mole fraction solubility of LNX was found to be highest in pure PEG-400 (1.71×10−2 at T =323.15K) and lowest in pure water (2.90×10−6 at T =298.15K) at all five different temperatures investigated. Thermodynamic function of LNX in different (PEG-400+water) mixtures was recorded as an endothermic, spontaneous and entropy driven. These results indicated that PEG-400 could be utilized as a good solvent for solubilization and stabilization of LNX in an aqueous media. |
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Solubility and thermodynamic function of lornoxicam in (PEG-400+water) mixtures at different temperatures |
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