The fate of human platelets exposed to porcine renal endothelium: a single-pass model of platelet uptake in domestic and genetically modified porcine organs
Thrombocytopenia may represent a significant challenge to the clinical application of solid-organ xenotransplantation. When studied in a pig-to-primate model, consumptive coagulopathy has challenged renal xenografts. New strategies of genetic manipulation have altered porcine carbohydrate profiles t...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Butler, James R. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Umfang: |
9 |
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| Übergeordnetes Werk: |
Enthalten in: Iatrogenic pneumothorax during hypoglossal nerve stimulator implantation - Arteaga, Alberto A. ELSEVIER, 2018, JSR : clinical and laboratory investigation : official publication of the Association for Academic Surgery : official publication of the Association of Veterans Administration Surgeons, Orlando, Fla |
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| Übergeordnetes Werk: |
volume:200 ; year:2016 ; number:2 ; pages:698-706 ; extent:9 |
| Links: |
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| DOI / URN: |
10.1016/j.jss.2015.08.034 |
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| 520 | |a Thrombocytopenia may represent a significant challenge to the clinical application of solid-organ xenotransplantation. When studied in a pig-to-primate model, consumptive coagulopathy has challenged renal xenografts. New strategies of genetic manipulation have altered porcine carbohydrate profiles to significantly reduce human antibody binding to pig cells. As this process continues to eliminate immunologic barriers to clinical xenotransplantation, the relationship between human platelets and pig organs must be considered. | ||
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10.1016/j.jss.2015.08.034 doi GBVA2016021000029.pica (DE-627)ELV01982369X (ELSEVIER)S0022-4804(15)00873-2 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.94 bkl Butler, James R. verfasserin aut The fate of human platelets exposed to porcine renal endothelium: a single-pass model of platelet uptake in domestic and genetically modified porcine organs 2016 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Thrombocytopenia may represent a significant challenge to the clinical application of solid-organ xenotransplantation. When studied in a pig-to-primate model, consumptive coagulopathy has challenged renal xenografts. New strategies of genetic manipulation have altered porcine carbohydrate profiles to significantly reduce human antibody binding to pig cells. As this process continues to eliminate immunologic barriers to clinical xenotransplantation, the relationship between human platelets and pig organs must be considered. Thrombocytopenia Elsevier Xenotransplantation Elsevier Platelets Elsevier Kidney Elsevier Martens, Gregory R. oth Li, Ping oth Wang, Zheng-Yu oth Estrada, Jose L. oth Ladowski, Joseph M. oth Tector, Matt oth Tector, A. Joseph oth Enthalten in Academic Press Arteaga, Alberto A. ELSEVIER Iatrogenic pneumothorax during hypoglossal nerve stimulator implantation 2018 JSR : clinical and laboratory investigation : official publication of the Association for Academic Surgery : official publication of the Association of Veterans Administration Surgeons Orlando, Fla (DE-627)ELV00028954X volume:200 year:2016 number:2 pages:698-706 extent:9 https://doi.org/10.1016/j.jss.2015.08.034 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.94 Hals-Nasen-Ohrenheilkunde VZ AR 200 2016 2 698-706 9 045F 610 |
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The fate of human platelets exposed to porcine renal endothelium: a single-pass model of platelet uptake in domestic and genetically modified porcine organs |
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Thrombocytopenia may represent a significant challenge to the clinical application of solid-organ xenotransplantation. When studied in a pig-to-primate model, consumptive coagulopathy has challenged renal xenografts. New strategies of genetic manipulation have altered porcine carbohydrate profiles to significantly reduce human antibody binding to pig cells. As this process continues to eliminate immunologic barriers to clinical xenotransplantation, the relationship between human platelets and pig organs must be considered. |
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Thrombocytopenia may represent a significant challenge to the clinical application of solid-organ xenotransplantation. When studied in a pig-to-primate model, consumptive coagulopathy has challenged renal xenografts. New strategies of genetic manipulation have altered porcine carbohydrate profiles to significantly reduce human antibody binding to pig cells. As this process continues to eliminate immunologic barriers to clinical xenotransplantation, the relationship between human platelets and pig organs must be considered. |
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Thrombocytopenia may represent a significant challenge to the clinical application of solid-organ xenotransplantation. When studied in a pig-to-primate model, consumptive coagulopathy has challenged renal xenografts. New strategies of genetic manipulation have altered porcine carbohydrate profiles to significantly reduce human antibody binding to pig cells. As this process continues to eliminate immunologic barriers to clinical xenotransplantation, the relationship between human platelets and pig organs must be considered. |
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The fate of human platelets exposed to porcine renal endothelium: a single-pass model of platelet uptake in domestic and genetically modified porcine organs |
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https://doi.org/10.1016/j.jss.2015.08.034 |
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Martens, Gregory R. Li, Ping Wang, Zheng-Yu Estrada, Jose L. Ladowski, Joseph M. Tector, Matt Tector, A. Joseph |
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Martens, Gregory R. Li, Ping Wang, Zheng-Yu Estrada, Jose L. Ladowski, Joseph M. Tector, Matt Tector, A. Joseph |
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10.1016/j.jss.2015.08.034 |
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2024-07-06T22:28:54.397Z |
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