Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival
• MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatical...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Cosgrove, Casey M. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2017 |
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| Umfang: |
8 |
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| Übergeordnetes Werk: |
Enthalten in: Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes - Gibson, Diane M. ELSEVIER, 2017, an international journal : official publication of the Society of Gynecologic Oncologists [u.a.], Orlando, Fla |
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| Übergeordnetes Werk: |
volume:146 ; year:2017 ; number:3 ; pages:588-595 ; extent:8 |
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| DOI / URN: |
10.1016/j.ygyno.2017.07.003 |
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| 520 | |a • MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatically in advanced stage endometrial cancer. • MMR defective tumors with MLH1 methylation may exhibit chemoresistance. | ||
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10.1016/j.ygyno.2017.07.003 doi GBVA2017001000002.pica (DE-627)ELV019945515 (ELSEVIER)S0090-8258(17)30980-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.11 bkl Cosgrove, Casey M. verfasserin aut Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatically in advanced stage endometrial cancer. • MMR defective tumors with MLH1 methylation may exhibit chemoresistance. Cohn, David E. oth Hampel, Heather oth Frankel, Wendy L. oth Jones, Dan oth McElroy, Joseph P. oth Suarez, Adrian A. oth Zhao, Weiqiang oth Chen, Wei oth Salani, Ritu oth Copeland, Larry J. oth O'Malley, David M. oth Fowler, Jeffrey M. oth Yilmaz, Ahmet oth Chassen, Alexis S. oth Pearlman, Rachel oth Goodfellow, Paul J. oth Backes, Floor J. oth Enthalten in Academic Press Gibson, Diane M. ELSEVIER Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes 2017 an international journal : official publication of the Society of Gynecologic Oncologists [u.a.] Orlando, Fla (DE-627)ELV000708127 volume:146 year:2017 number:3 pages:588-595 extent:8 https://doi.org/10.1016/j.ygyno.2017.07.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.11 Präventivmedizin VZ AR 146 2017 3 588-595 8 045F 610 |
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10.1016/j.ygyno.2017.07.003 doi GBVA2017001000002.pica (DE-627)ELV019945515 (ELSEVIER)S0090-8258(17)30980-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.11 bkl Cosgrove, Casey M. verfasserin aut Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatically in advanced stage endometrial cancer. • MMR defective tumors with MLH1 methylation may exhibit chemoresistance. Cohn, David E. oth Hampel, Heather oth Frankel, Wendy L. oth Jones, Dan oth McElroy, Joseph P. oth Suarez, Adrian A. oth Zhao, Weiqiang oth Chen, Wei oth Salani, Ritu oth Copeland, Larry J. oth O'Malley, David M. oth Fowler, Jeffrey M. oth Yilmaz, Ahmet oth Chassen, Alexis S. oth Pearlman, Rachel oth Goodfellow, Paul J. oth Backes, Floor J. oth Enthalten in Academic Press Gibson, Diane M. ELSEVIER Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes 2017 an international journal : official publication of the Society of Gynecologic Oncologists [u.a.] Orlando, Fla (DE-627)ELV000708127 volume:146 year:2017 number:3 pages:588-595 extent:8 https://doi.org/10.1016/j.ygyno.2017.07.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.11 Präventivmedizin VZ AR 146 2017 3 588-595 8 045F 610 |
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10.1016/j.ygyno.2017.07.003 doi GBVA2017001000002.pica (DE-627)ELV019945515 (ELSEVIER)S0090-8258(17)30980-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.11 bkl Cosgrove, Casey M. verfasserin aut Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatically in advanced stage endometrial cancer. • MMR defective tumors with MLH1 methylation may exhibit chemoresistance. Cohn, David E. oth Hampel, Heather oth Frankel, Wendy L. oth Jones, Dan oth McElroy, Joseph P. oth Suarez, Adrian A. oth Zhao, Weiqiang oth Chen, Wei oth Salani, Ritu oth Copeland, Larry J. oth O'Malley, David M. oth Fowler, Jeffrey M. oth Yilmaz, Ahmet oth Chassen, Alexis S. oth Pearlman, Rachel oth Goodfellow, Paul J. oth Backes, Floor J. oth Enthalten in Academic Press Gibson, Diane M. ELSEVIER Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes 2017 an international journal : official publication of the Society of Gynecologic Oncologists [u.a.] Orlando, Fla (DE-627)ELV000708127 volume:146 year:2017 number:3 pages:588-595 extent:8 https://doi.org/10.1016/j.ygyno.2017.07.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.11 Präventivmedizin VZ AR 146 2017 3 588-595 8 045F 610 |
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10.1016/j.ygyno.2017.07.003 doi GBVA2017001000002.pica (DE-627)ELV019945515 (ELSEVIER)S0090-8258(17)30980-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.11 bkl Cosgrove, Casey M. verfasserin aut Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatically in advanced stage endometrial cancer. • MMR defective tumors with MLH1 methylation may exhibit chemoresistance. Cohn, David E. oth Hampel, Heather oth Frankel, Wendy L. oth Jones, Dan oth McElroy, Joseph P. oth Suarez, Adrian A. oth Zhao, Weiqiang oth Chen, Wei oth Salani, Ritu oth Copeland, Larry J. oth O'Malley, David M. oth Fowler, Jeffrey M. oth Yilmaz, Ahmet oth Chassen, Alexis S. oth Pearlman, Rachel oth Goodfellow, Paul J. oth Backes, Floor J. oth Enthalten in Academic Press Gibson, Diane M. ELSEVIER Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes 2017 an international journal : official publication of the Society of Gynecologic Oncologists [u.a.] Orlando, Fla (DE-627)ELV000708127 volume:146 year:2017 number:3 pages:588-595 extent:8 https://doi.org/10.1016/j.ygyno.2017.07.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.11 Präventivmedizin VZ AR 146 2017 3 588-595 8 045F 610 |
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10.1016/j.ygyno.2017.07.003 doi GBVA2017001000002.pica (DE-627)ELV019945515 (ELSEVIER)S0090-8258(17)30980-0 DE-627 ger DE-627 rakwb eng 610 610 DE-600 610 VZ 44.11 bkl Cosgrove, Casey M. verfasserin aut Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival 2017 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatically in advanced stage endometrial cancer. • MMR defective tumors with MLH1 methylation may exhibit chemoresistance. Cohn, David E. oth Hampel, Heather oth Frankel, Wendy L. oth Jones, Dan oth McElroy, Joseph P. oth Suarez, Adrian A. oth Zhao, Weiqiang oth Chen, Wei oth Salani, Ritu oth Copeland, Larry J. oth O'Malley, David M. oth Fowler, Jeffrey M. oth Yilmaz, Ahmet oth Chassen, Alexis S. oth Pearlman, Rachel oth Goodfellow, Paul J. oth Backes, Floor J. oth Enthalten in Academic Press Gibson, Diane M. ELSEVIER Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes 2017 an international journal : official publication of the Society of Gynecologic Oncologists [u.a.] Orlando, Fla (DE-627)ELV000708127 volume:146 year:2017 number:3 pages:588-595 extent:8 https://doi.org/10.1016/j.ygyno.2017.07.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.11 Präventivmedizin VZ AR 146 2017 3 588-595 8 045F 610 |
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Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival |
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(DE-627)ELV019945515 (ELSEVIER)S0090-8258(17)30980-0 |
| title_full |
Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival |
| author_sort |
Cosgrove, Casey M. |
| journal |
Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes |
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Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes |
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eng |
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600 - Technology |
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2017 |
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588 |
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Cosgrove, Casey M. |
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146 |
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Cosgrove, Casey M. |
| doi_str_mv |
10.1016/j.ygyno.2017.07.003 |
| dewey-full |
610 |
| title_sort |
epigenetic silencing of mlh1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival |
| title_auth |
Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival |
| abstract |
• MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatically in advanced stage endometrial cancer. • MMR defective tumors with MLH1 methylation may exhibit chemoresistance. |
| abstractGer |
• MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatically in advanced stage endometrial cancer. • MMR defective tumors with MLH1 methylation may exhibit chemoresistance. |
| abstract_unstemmed |
• MLH1 methylated endometrial tumors have poor prognostic features including larger size. • Tumor volume and mismatch repair class are associated with lymph node involvement. • Women with MLH1 methylated tumors have reduced recurrence-free survival. • Recurrence rate by MMR class differed dramatically in advanced stage endometrial cancer. • MMR defective tumors with MLH1 methylation may exhibit chemoresistance. |
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GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
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3 |
| title_short |
Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival |
| url |
https://doi.org/10.1016/j.ygyno.2017.07.003 |
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Cohn, David E. Hampel, Heather Frankel, Wendy L. Jones, Dan McElroy, Joseph P. Suarez, Adrian A. Zhao, Weiqiang Chen, Wei Salani, Ritu Copeland, Larry J. O'Malley, David M. Fowler, Jeffrey M. Yilmaz, Ahmet Chassen, Alexis S. Pearlman, Rachel Goodfellow, Paul J. Backes, Floor J. |
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Cohn, David E. Hampel, Heather Frankel, Wendy L. Jones, Dan McElroy, Joseph P. Suarez, Adrian A. Zhao, Weiqiang Chen, Wei Salani, Ritu Copeland, Larry J. O'Malley, David M. Fowler, Jeffrey M. Yilmaz, Ahmet Chassen, Alexis S. Pearlman, Rachel Goodfellow, Paul J. Backes, Floor J. |
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10.1016/j.ygyno.2017.07.003 |
| up_date |
2024-07-06T22:48:26.619Z |
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