Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats
Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have d...
Ausführliche Beschreibung
Autor*in: |
Jiao, Yukun [verfasserIn] |
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Sprache: |
Englisch |
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2017transfer abstract |
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Schlagwörter: |
Citric acid (PubChem CID: 22230) Hematoxylin (PubChem CID: 10603) Tween-20 (PubChem CID: 443314) Trisodium citrate dehydrate (PubChem CID: 71474) |
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Umfang: |
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Übergeordnetes Werk: |
Enthalten in: Oocyte provision as a (quasi) social market: Insights from Spain - Degli Esposti, Sara ELSEVIER, 2019, an interdisciplinary journal devoted to bioscientific research on indigenous drugs : the official journal of the International Society of Ethnopharmacology, New York, NY [u.a.] |
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Übergeordnetes Werk: |
volume:199 ; year:2017 ; day:6 ; month:03 ; pages:119-127 ; extent:9 |
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DOI / URN: |
10.1016/j.jep.2017.02.003 |
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520 | |a Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. | ||
520 | |a Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. | ||
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10.1016/j.jep.2017.02.003 doi GBVA2017012000013.pica (DE-627)ELV02031745X (ELSEVIER)S0378-8741(17)30420-8 DE-627 ger DE-627 rakwb eng 610 390 610 DE-600 390 DE-600 300 610 VZ 44.06 bkl Jiao, Yukun verfasserin aut Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Citric acid (PubChem CID: 22230) Elsevier Hematoxylin (PubChem CID: 10603) Elsevier Eosin Y (PubChem CID: 11048) Elsevier Ethanol (PubChem CID: 702) Elsevier Glucose (PubChem CID: 107526) Elsevier Tween-20 (PubChem CID: 443314) Elsevier Trisodium citrate dehydrate (PubChem CID: 71474) Elsevier Methanol (PubChem CID: 887) Elsevier Streptozotocin (PubChem CID: 29327) Elsevier Glycerol (PubChem CID: 753) Elsevier Wang, Xueqian oth Jiang, Xiang oth Kong, Fansheng oth Wang, Shumei oth Yan, Chunyan oth Enthalten in Elsevier Degli Esposti, Sara ELSEVIER Oocyte provision as a (quasi) social market: Insights from Spain 2019 an interdisciplinary journal devoted to bioscientific research on indigenous drugs : the official journal of the International Society of Ethnopharmacology New York, NY [u.a.] (DE-627)ELV002571021 volume:199 year:2017 day:6 month:03 pages:119-127 extent:9 https://doi.org/10.1016/j.jep.2017.02.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.06 Medizinsoziologie VZ AR 199 2017 6 0306 119-127 9 045F 610 |
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10.1016/j.jep.2017.02.003 doi GBVA2017012000013.pica (DE-627)ELV02031745X (ELSEVIER)S0378-8741(17)30420-8 DE-627 ger DE-627 rakwb eng 610 390 610 DE-600 390 DE-600 300 610 VZ 44.06 bkl Jiao, Yukun verfasserin aut Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Citric acid (PubChem CID: 22230) Elsevier Hematoxylin (PubChem CID: 10603) Elsevier Eosin Y (PubChem CID: 11048) Elsevier Ethanol (PubChem CID: 702) Elsevier Glucose (PubChem CID: 107526) Elsevier Tween-20 (PubChem CID: 443314) Elsevier Trisodium citrate dehydrate (PubChem CID: 71474) Elsevier Methanol (PubChem CID: 887) Elsevier Streptozotocin (PubChem CID: 29327) Elsevier Glycerol (PubChem CID: 753) Elsevier Wang, Xueqian oth Jiang, Xiang oth Kong, Fansheng oth Wang, Shumei oth Yan, Chunyan oth Enthalten in Elsevier Degli Esposti, Sara ELSEVIER Oocyte provision as a (quasi) social market: Insights from Spain 2019 an interdisciplinary journal devoted to bioscientific research on indigenous drugs : the official journal of the International Society of Ethnopharmacology New York, NY [u.a.] (DE-627)ELV002571021 volume:199 year:2017 day:6 month:03 pages:119-127 extent:9 https://doi.org/10.1016/j.jep.2017.02.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.06 Medizinsoziologie VZ AR 199 2017 6 0306 119-127 9 045F 610 |
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10.1016/j.jep.2017.02.003 doi GBVA2017012000013.pica (DE-627)ELV02031745X (ELSEVIER)S0378-8741(17)30420-8 DE-627 ger DE-627 rakwb eng 610 390 610 DE-600 390 DE-600 300 610 VZ 44.06 bkl Jiao, Yukun verfasserin aut Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Citric acid (PubChem CID: 22230) Elsevier Hematoxylin (PubChem CID: 10603) Elsevier Eosin Y (PubChem CID: 11048) Elsevier Ethanol (PubChem CID: 702) Elsevier Glucose (PubChem CID: 107526) Elsevier Tween-20 (PubChem CID: 443314) Elsevier Trisodium citrate dehydrate (PubChem CID: 71474) Elsevier Methanol (PubChem CID: 887) Elsevier Streptozotocin (PubChem CID: 29327) Elsevier Glycerol (PubChem CID: 753) Elsevier Wang, Xueqian oth Jiang, Xiang oth Kong, Fansheng oth Wang, Shumei oth Yan, Chunyan oth Enthalten in Elsevier Degli Esposti, Sara ELSEVIER Oocyte provision as a (quasi) social market: Insights from Spain 2019 an interdisciplinary journal devoted to bioscientific research on indigenous drugs : the official journal of the International Society of Ethnopharmacology New York, NY [u.a.] (DE-627)ELV002571021 volume:199 year:2017 day:6 month:03 pages:119-127 extent:9 https://doi.org/10.1016/j.jep.2017.02.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.06 Medizinsoziologie VZ AR 199 2017 6 0306 119-127 9 045F 610 |
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10.1016/j.jep.2017.02.003 doi GBVA2017012000013.pica (DE-627)ELV02031745X (ELSEVIER)S0378-8741(17)30420-8 DE-627 ger DE-627 rakwb eng 610 390 610 DE-600 390 DE-600 300 610 VZ 44.06 bkl Jiao, Yukun verfasserin aut Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Citric acid (PubChem CID: 22230) Elsevier Hematoxylin (PubChem CID: 10603) Elsevier Eosin Y (PubChem CID: 11048) Elsevier Ethanol (PubChem CID: 702) Elsevier Glucose (PubChem CID: 107526) Elsevier Tween-20 (PubChem CID: 443314) Elsevier Trisodium citrate dehydrate (PubChem CID: 71474) Elsevier Methanol (PubChem CID: 887) Elsevier Streptozotocin (PubChem CID: 29327) Elsevier Glycerol (PubChem CID: 753) Elsevier Wang, Xueqian oth Jiang, Xiang oth Kong, Fansheng oth Wang, Shumei oth Yan, Chunyan oth Enthalten in Elsevier Degli Esposti, Sara ELSEVIER Oocyte provision as a (quasi) social market: Insights from Spain 2019 an interdisciplinary journal devoted to bioscientific research on indigenous drugs : the official journal of the International Society of Ethnopharmacology New York, NY [u.a.] (DE-627)ELV002571021 volume:199 year:2017 day:6 month:03 pages:119-127 extent:9 https://doi.org/10.1016/j.jep.2017.02.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.06 Medizinsoziologie VZ AR 199 2017 6 0306 119-127 9 045F 610 |
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10.1016/j.jep.2017.02.003 doi GBVA2017012000013.pica (DE-627)ELV02031745X (ELSEVIER)S0378-8741(17)30420-8 DE-627 ger DE-627 rakwb eng 610 390 610 DE-600 390 DE-600 300 610 VZ 44.06 bkl Jiao, Yukun verfasserin aut Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats 2017transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. Citric acid (PubChem CID: 22230) Elsevier Hematoxylin (PubChem CID: 10603) Elsevier Eosin Y (PubChem CID: 11048) Elsevier Ethanol (PubChem CID: 702) Elsevier Glucose (PubChem CID: 107526) Elsevier Tween-20 (PubChem CID: 443314) Elsevier Trisodium citrate dehydrate (PubChem CID: 71474) Elsevier Methanol (PubChem CID: 887) Elsevier Streptozotocin (PubChem CID: 29327) Elsevier Glycerol (PubChem CID: 753) Elsevier Wang, Xueqian oth Jiang, Xiang oth Kong, Fansheng oth Wang, Shumei oth Yan, Chunyan oth Enthalten in Elsevier Degli Esposti, Sara ELSEVIER Oocyte provision as a (quasi) social market: Insights from Spain 2019 an interdisciplinary journal devoted to bioscientific research on indigenous drugs : the official journal of the International Society of Ethnopharmacology New York, NY [u.a.] (DE-627)ELV002571021 volume:199 year:2017 day:6 month:03 pages:119-127 extent:9 https://doi.org/10.1016/j.jep.2017.02.003 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.06 Medizinsoziologie VZ AR 199 2017 6 0306 119-127 9 045F 610 |
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Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats |
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Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. |
abstractGer |
Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. |
abstract_unstemmed |
Type 2 diabetes mellitus (T2DM) is becoming a serious threat to human health. The fruit of Morus alba L. is widely used as a traditional Chinese medicine for the treatment of DM, dizziness, tinnitus, insomnia, and premature graying, as well as to protect the liver and kidneys. Several studies have demonstrated that the aqueous extracts of the roots bark, leaves, and ramuli of mulberry, which are known to contain polyphenols and polysaccharides, have antihyperglycemic and antihyperlipidemic activities. The aim of the present study was to further investigate the active polysaccharides from M. alba fruit by evaluating the antidiabetic activities of different fractions on T2DM rats and elucidate the mechanism underlying these activities. |
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