Fc receptor-targeting of immunogen as a strategy for enhanced antigen loading, vaccination, and protection using intranasally administered antigen-pulsed dendritic cells
Highlights • Efficacy: Effective i.n. vaccination via DCs pulsed ex vivo with FcγR-targeted Ag is demonstrated. • Immune responses: Mucosal, peripheral, humoral, and cellular immune responses are enhanced. • Immune advantages: Traditional adjuvant is not required and inhibition via FcγRIIB is absent...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Pham, Giang H. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014 |
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| Schlagwörter: |
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| Umfang: |
9 |
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| Übergeordnetes Werk: |
Enthalten in: Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement - Li, Yaoyao ELSEVIER, 2022, Amsterdam |
|---|---|
| Übergeordnetes Werk: |
volume:32 ; year:2014 ; number:40 ; day:8 ; month:09 ; pages:5212-5220 ; extent:9 |
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| DOI / URN: |
10.1016/j.vaccine.2014.07.050 |
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10.1016/j.vaccine.2014.07.050 doi GBVA2014008000005.pica (DE-627)ELV022587500 (ELSEVIER)S0264-410X(14)00993-1 DE-627 ger DE-627 rakwb eng 610 610 DE-600 630 640 VZ 48.00 bkl Pham, Giang H. verfasserin aut Fc receptor-targeting of immunogen as a strategy for enhanced antigen loading, vaccination, and protection using intranasally administered antigen-pulsed dendritic cells 2014 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Highlights • Efficacy: Effective i.n. vaccination via DCs pulsed ex vivo with FcγR-targeted Ag is demonstrated. • Immune responses: Mucosal, peripheral, humoral, and cellular immune responses are enhanced. • Immune advantages: Traditional adjuvant is not required and inhibition via FcγRIIB is absent. • Clinical advantages: Ability to use a less invasive i.n. route and stimulate CD4 and CD8 responses. • Applications: Vaccines and therapeutics against chronic infectious diseases and cancer. Fcγ receptor-targeted vaccine Elsevier Intranasal vaccine Elsevier Vaccine platform Elsevier Chronic infection Elsevier Dendritic cell vaccine Elsevier Cancer Elsevier Iglesias, Bibiana V. oth Gosselin, Edmund J. oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:32 year:2014 number:40 day:8 month:09 pages:5212-5220 extent:9 https://doi.org/10.1016/j.vaccine.2014.07.050 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 32 2014 40 8 0908 5212-5220 9 045F 610 |
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Fc receptor-targeting of immunogen as a strategy for enhanced antigen loading, vaccination, and protection using intranasally administered antigen-pulsed dendritic cells |
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Highlights • Efficacy: Effective i.n. vaccination via DCs pulsed ex vivo with FcγR-targeted Ag is demonstrated. • Immune responses: Mucosal, peripheral, humoral, and cellular immune responses are enhanced. • Immune advantages: Traditional adjuvant is not required and inhibition via FcγRIIB is absent. • Clinical advantages: Ability to use a less invasive i.n. route and stimulate CD4 and CD8 responses. • Applications: Vaccines and therapeutics against chronic infectious diseases and cancer. |
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Highlights • Efficacy: Effective i.n. vaccination via DCs pulsed ex vivo with FcγR-targeted Ag is demonstrated. • Immune responses: Mucosal, peripheral, humoral, and cellular immune responses are enhanced. • Immune advantages: Traditional adjuvant is not required and inhibition via FcγRIIB is absent. • Clinical advantages: Ability to use a less invasive i.n. route and stimulate CD4 and CD8 responses. • Applications: Vaccines and therapeutics against chronic infectious diseases and cancer. |
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Highlights • Efficacy: Effective i.n. vaccination via DCs pulsed ex vivo with FcγR-targeted Ag is demonstrated. • Immune responses: Mucosal, peripheral, humoral, and cellular immune responses are enhanced. • Immune advantages: Traditional adjuvant is not required and inhibition via FcγRIIB is absent. • Clinical advantages: Ability to use a less invasive i.n. route and stimulate CD4 and CD8 responses. • Applications: Vaccines and therapeutics against chronic infectious diseases and cancer. |
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Fc receptor-targeting of immunogen as a strategy for enhanced antigen loading, vaccination, and protection using intranasally administered antigen-pulsed dendritic cells |
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