Effect of particle size on the speed and resolution of chiral separations using supercritical fluid chromatography

• Smaller particle columns were evaluated for fast chiral SFC separations. • Smaller 3μm particles vs. 5μm particles showed higher optimum linear velocity. • The van Deemter plots showed typical pattern observed in HPLC. • Use of 3mL/min flow rate on the OD-3 column with 150×4.6mm i.d. is recommende...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Biba, Mirlinda [verfasserIn]

Regalado, Erik L.

Wu, Naijun

Welch, Christopher J.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2014

Schlagwörter:

Small particle size

Fast separations.

Chiral separation

High-throughput analysis

Supercritical fluid chromatography

Umfang:

7

Übergeordnetes Werk:

Enthalten in: Defense development: The role of co-creation in filling the gap between policy-makers and technology development - Liwång, Hans ELSEVIER, 2022, including electrophoresis, mass spectrometry and other separation and detection methods, New York, NY [u.a.]

Übergeordnetes Werk:

volume:1363 ; year:2014 ; day:10 ; month:10 ; pages:250-256 ; extent:7

Links:

Volltext

DOI / URN:

10.1016/j.chroma.2014.07.010

Katalog-ID:

ELV023104503

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