Clinical deployment of antibodies for treatment of melanoma

• Melanoma treatment has been transformed using T-cell checkpoint antibodies. • Antibodies to CTLA-4 and PD-1 have had the largest impact on melanoma management. • Combination T-cell checkpoint therapy holds great promise for clinical development. • OX40 and 4-1BB are T cell costimulators with clini...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Curti, Brendan D. [verfasserIn]

Urba, Walter J.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2015

Schlagwörter:

OX40

Melanoma

4-1BB

CTLA-4

PD-1

Umfang:

10

Übergeordnetes Werk:

Enthalten in: Letter regarding the article: Changes in BNP and cardiac troponin I after high-intensity interval and endurance exercise in heart failure patients and healthy controls - Gayda, Mathieu ELSEVIER, 2015, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:67 ; year:2015 ; number:2 ; pages:18-27 ; extent:10

Links:

Volltext

DOI / URN:

10.1016/j.molimm.2015.01.025

Katalog-ID:

ELV023268697

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