Increased homocysteine levels correlate with the communication deficit in children with autism spectrum disorder
The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity...
Ausführliche Beschreibung
Gespeichert in:
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Puig-Alcaraz, Carmen [verfasserIn] |
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E-Artikel |
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Englisch |
| Erschienen: |
2015transfer abstract |
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7 |
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| Übergeordnetes Werk: |
Enthalten in: No title available - 229(2015), 3 vom: 30., Seite 1031-1037 |
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volume:229 ; year:2015 ; number:3 ; day:30 ; month:10 ; pages:1031-1037 ; extent:7 |
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| DOI / URN: |
10.1016/j.psychres.2015.05.021 |
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| 520 | |a The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. | ||
| 520 | |a The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. | ||
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10.1016/j.psychres.2015.05.021 doi /export/home/cbs_olc/import_discovery/elsevier/convert/GBV-Archive_01_06_pica_neu/GBVA2015004000011.pica (DE-627)ELV023303182 (ELSEVIER)S0165-1781(15)00290-5 DE-627 ger DE-627 rakwb eng Puig-Alcaraz, Carmen verfasserin aut Increased homocysteine levels correlate with the communication deficit in children with autism spectrum disorder 2015transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. Core symptoms Elsevier Biomarker Elsevier Language development Elsevier Metabolism Elsevier Homocysteine Elsevier Autism spectrum disorder Elsevier Fuentes-Albero, Milagros oth Calderón, Jesús oth Garrote, Dolores oth Cauli, Omar oth Enthalten in No title available 229(2015), 3 vom: 30., Seite 1031-1037 (DE-627)ELV013759760 (DE-600)5-1781 nnns volume:229 year:2015 number:3 day:30 month:10 pages:1031-1037 extent:7 https://doi.org/10.1016/j.psychres.2015.05.021 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U AR 229 2015 3 30 1030 1031-1037 7 |
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10.1016/j.psychres.2015.05.021 doi /export/home/cbs_olc/import_discovery/elsevier/convert/GBV-Archive_01_06_pica_neu/GBVA2015004000011.pica (DE-627)ELV023303182 (ELSEVIER)S0165-1781(15)00290-5 DE-627 ger DE-627 rakwb eng Puig-Alcaraz, Carmen verfasserin aut Increased homocysteine levels correlate with the communication deficit in children with autism spectrum disorder 2015transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. Core symptoms Elsevier Biomarker Elsevier Language development Elsevier Metabolism Elsevier Homocysteine Elsevier Autism spectrum disorder Elsevier Fuentes-Albero, Milagros oth Calderón, Jesús oth Garrote, Dolores oth Cauli, Omar oth Enthalten in No title available 229(2015), 3 vom: 30., Seite 1031-1037 (DE-627)ELV013759760 (DE-600)5-1781 nnns volume:229 year:2015 number:3 day:30 month:10 pages:1031-1037 extent:7 https://doi.org/10.1016/j.psychres.2015.05.021 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U AR 229 2015 3 30 1030 1031-1037 7 |
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10.1016/j.psychres.2015.05.021 doi /export/home/cbs_olc/import_discovery/elsevier/convert/GBV-Archive_01_06_pica_neu/GBVA2015004000011.pica (DE-627)ELV023303182 (ELSEVIER)S0165-1781(15)00290-5 DE-627 ger DE-627 rakwb eng Puig-Alcaraz, Carmen verfasserin aut Increased homocysteine levels correlate with the communication deficit in children with autism spectrum disorder 2015transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. Core symptoms Elsevier Biomarker Elsevier Language development Elsevier Metabolism Elsevier Homocysteine Elsevier Autism spectrum disorder Elsevier Fuentes-Albero, Milagros oth Calderón, Jesús oth Garrote, Dolores oth Cauli, Omar oth Enthalten in No title available 229(2015), 3 vom: 30., Seite 1031-1037 (DE-627)ELV013759760 (DE-600)5-1781 nnns volume:229 year:2015 number:3 day:30 month:10 pages:1031-1037 extent:7 https://doi.org/10.1016/j.psychres.2015.05.021 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U AR 229 2015 3 30 1030 1031-1037 7 |
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Increased homocysteine levels correlate with the communication deficit in children with autism spectrum disorder |
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Increased homocysteine levels correlate with the communication deficit in children with autism spectrum disorder |
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Puig-Alcaraz, Carmen |
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10.1016/j.psychres.2015.05.021 |
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increased homocysteine levels correlate with the communication deficit in children with autism spectrum disorder |
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Increased homocysteine levels correlate with the communication deficit in children with autism spectrum disorder |
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The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. |
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The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. |
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The clinical significance of high levels of homocysteine in autism spectrum disorder (ASD) is unknown. An experimental study was conducted in order to evaluate the concentration of homocysteine in children with ASD and typically developing children and to analyse any relationships with the severity of core symptoms of ASD and other clinical features (drugs, co-morbidities, gender, age, diet). Core symptoms of autism were evaluated by DSM-IV criteria. Homocysteine, glutathione, methionine, 3-nitrotyrosine were measured in urine. The increase in homocysteine concentration was significantly and directly correlated with the severity of the deficit in communication skills, but was unrelated to deficit in socialisation or repetitive/restricted behaviour. Urinary homocysteine concentration may be a possible biomarker for communication deficits in ASD and a potential diagnostic tool useful to evaluate new treatment options since no treatment for core symptoms of ASD are available. |
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Increased homocysteine levels correlate with the communication deficit in children with autism spectrum disorder |
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Fuentes-Albero, Milagros Calderón, Jesús Garrote, Dolores Cauli, Omar |
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