Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma
• The safety and immunogenicity of hTERT-derived peptide (hTERT461) as a peptide vaccine to hepatocellular carcinoma was confirmed. • The post-vaccinated increase in hTERT461 peptide-specific T cells was due to the increase in cells with the effector memory phenotype. • We showed the possible effica...
Ausführliche Beschreibung
Autor*in: |
Mizukoshi, Eishiro [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2015 |
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Umfang: |
8 |
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Enthalten in: GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome - Hao, Lijun ELSEVIER, 2015, an international journal providing a forum for original and pertinent contributions in cancer research, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:364 ; year:2015 ; number:2 ; day:10 ; month:08 ; pages:98-105 ; extent:8 |
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DOI / URN: |
10.1016/j.canlet.2015.04.031 |
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10.1016/j.canlet.2015.04.031 doi GBVA2015010000010.pica (DE-627)ELV023514078 (ELSEVIER)S0304-3835(15)00338-9 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 600 690 VZ 51.00 bkl 51.32 bkl Mizukoshi, Eishiro verfasserin aut Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma 2015 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The safety and immunogenicity of hTERT-derived peptide (hTERT461) as a peptide vaccine to hepatocellular carcinoma was confirmed. • The post-vaccinated increase in hTERT461 peptide-specific T cells was due to the increase in cells with the effector memory phenotype. • We showed the possible efficacy of hTERT-derived peptide vaccine in preventing HCC recurrence after curative treatments. • We also succeeded in obtaining the hTERT-specific T cell receptors from hTERT461 peptide-specific T cells. Nakagawa, Hidetoshi oth Kitahara, Masaaki oth Yamashita, Tatsuya oth Arai, Kuniaki oth Sunagozaka, Hajime oth Fushimi, Kazumi oth Kobayashi, Eiji oth Kishi, Hiroyuki oth Muraguchi, Atsushi oth Kaneko, Shuichi oth Enthalten in Elsevier Science Hao, Lijun ELSEVIER GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome 2015 an international journal providing a forum for original and pertinent contributions in cancer research Amsterdam [u.a.] (DE-627)ELV013094742 volume:364 year:2015 number:2 day:10 month:08 pages:98-105 extent:8 https://doi.org/10.1016/j.canlet.2015.04.031 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_11 GBV_ILN_40 51.00 Werkstoffkunde: Allgemeines VZ 51.32 Werkstoffmechanik VZ AR 364 2015 2 10 0810 98-105 8 045F 570 |
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10.1016/j.canlet.2015.04.031 doi GBVA2015010000010.pica (DE-627)ELV023514078 (ELSEVIER)S0304-3835(15)00338-9 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 600 690 VZ 51.00 bkl 51.32 bkl Mizukoshi, Eishiro verfasserin aut Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma 2015 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The safety and immunogenicity of hTERT-derived peptide (hTERT461) as a peptide vaccine to hepatocellular carcinoma was confirmed. • The post-vaccinated increase in hTERT461 peptide-specific T cells was due to the increase in cells with the effector memory phenotype. • We showed the possible efficacy of hTERT-derived peptide vaccine in preventing HCC recurrence after curative treatments. • We also succeeded in obtaining the hTERT-specific T cell receptors from hTERT461 peptide-specific T cells. Nakagawa, Hidetoshi oth Kitahara, Masaaki oth Yamashita, Tatsuya oth Arai, Kuniaki oth Sunagozaka, Hajime oth Fushimi, Kazumi oth Kobayashi, Eiji oth Kishi, Hiroyuki oth Muraguchi, Atsushi oth Kaneko, Shuichi oth Enthalten in Elsevier Science Hao, Lijun ELSEVIER GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome 2015 an international journal providing a forum for original and pertinent contributions in cancer research Amsterdam [u.a.] (DE-627)ELV013094742 volume:364 year:2015 number:2 day:10 month:08 pages:98-105 extent:8 https://doi.org/10.1016/j.canlet.2015.04.031 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_11 GBV_ILN_40 51.00 Werkstoffkunde: Allgemeines VZ 51.32 Werkstoffmechanik VZ AR 364 2015 2 10 0810 98-105 8 045F 570 |
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10.1016/j.canlet.2015.04.031 doi GBVA2015010000010.pica (DE-627)ELV023514078 (ELSEVIER)S0304-3835(15)00338-9 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 600 690 VZ 51.00 bkl 51.32 bkl Mizukoshi, Eishiro verfasserin aut Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma 2015 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The safety and immunogenicity of hTERT-derived peptide (hTERT461) as a peptide vaccine to hepatocellular carcinoma was confirmed. • The post-vaccinated increase in hTERT461 peptide-specific T cells was due to the increase in cells with the effector memory phenotype. • We showed the possible efficacy of hTERT-derived peptide vaccine in preventing HCC recurrence after curative treatments. • We also succeeded in obtaining the hTERT-specific T cell receptors from hTERT461 peptide-specific T cells. Nakagawa, Hidetoshi oth Kitahara, Masaaki oth Yamashita, Tatsuya oth Arai, Kuniaki oth Sunagozaka, Hajime oth Fushimi, Kazumi oth Kobayashi, Eiji oth Kishi, Hiroyuki oth Muraguchi, Atsushi oth Kaneko, Shuichi oth Enthalten in Elsevier Science Hao, Lijun ELSEVIER GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome 2015 an international journal providing a forum for original and pertinent contributions in cancer research Amsterdam [u.a.] (DE-627)ELV013094742 volume:364 year:2015 number:2 day:10 month:08 pages:98-105 extent:8 https://doi.org/10.1016/j.canlet.2015.04.031 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_11 GBV_ILN_40 51.00 Werkstoffkunde: Allgemeines VZ 51.32 Werkstoffmechanik VZ AR 364 2015 2 10 0810 98-105 8 045F 570 |
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10.1016/j.canlet.2015.04.031 doi GBVA2015010000010.pica (DE-627)ELV023514078 (ELSEVIER)S0304-3835(15)00338-9 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 600 690 VZ 51.00 bkl 51.32 bkl Mizukoshi, Eishiro verfasserin aut Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma 2015 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The safety and immunogenicity of hTERT-derived peptide (hTERT461) as a peptide vaccine to hepatocellular carcinoma was confirmed. • The post-vaccinated increase in hTERT461 peptide-specific T cells was due to the increase in cells with the effector memory phenotype. • We showed the possible efficacy of hTERT-derived peptide vaccine in preventing HCC recurrence after curative treatments. • We also succeeded in obtaining the hTERT-specific T cell receptors from hTERT461 peptide-specific T cells. Nakagawa, Hidetoshi oth Kitahara, Masaaki oth Yamashita, Tatsuya oth Arai, Kuniaki oth Sunagozaka, Hajime oth Fushimi, Kazumi oth Kobayashi, Eiji oth Kishi, Hiroyuki oth Muraguchi, Atsushi oth Kaneko, Shuichi oth Enthalten in Elsevier Science Hao, Lijun ELSEVIER GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome 2015 an international journal providing a forum for original and pertinent contributions in cancer research Amsterdam [u.a.] (DE-627)ELV013094742 volume:364 year:2015 number:2 day:10 month:08 pages:98-105 extent:8 https://doi.org/10.1016/j.canlet.2015.04.031 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_11 GBV_ILN_40 51.00 Werkstoffkunde: Allgemeines VZ 51.32 Werkstoffmechanik VZ AR 364 2015 2 10 0810 98-105 8 045F 570 |
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10.1016/j.canlet.2015.04.031 doi GBVA2015010000010.pica (DE-627)ELV023514078 (ELSEVIER)S0304-3835(15)00338-9 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 600 690 VZ 51.00 bkl 51.32 bkl Mizukoshi, Eishiro verfasserin aut Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma 2015 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The safety and immunogenicity of hTERT-derived peptide (hTERT461) as a peptide vaccine to hepatocellular carcinoma was confirmed. • The post-vaccinated increase in hTERT461 peptide-specific T cells was due to the increase in cells with the effector memory phenotype. • We showed the possible efficacy of hTERT-derived peptide vaccine in preventing HCC recurrence after curative treatments. • We also succeeded in obtaining the hTERT-specific T cell receptors from hTERT461 peptide-specific T cells. Nakagawa, Hidetoshi oth Kitahara, Masaaki oth Yamashita, Tatsuya oth Arai, Kuniaki oth Sunagozaka, Hajime oth Fushimi, Kazumi oth Kobayashi, Eiji oth Kishi, Hiroyuki oth Muraguchi, Atsushi oth Kaneko, Shuichi oth Enthalten in Elsevier Science Hao, Lijun ELSEVIER GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome 2015 an international journal providing a forum for original and pertinent contributions in cancer research Amsterdam [u.a.] (DE-627)ELV013094742 volume:364 year:2015 number:2 day:10 month:08 pages:98-105 extent:8 https://doi.org/10.1016/j.canlet.2015.04.031 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_11 GBV_ILN_40 51.00 Werkstoffkunde: Allgemeines VZ 51.32 Werkstoffmechanik VZ AR 364 2015 2 10 0810 98-105 8 045F 570 |
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Mizukoshi, Eishiro |
doi_str_mv |
10.1016/j.canlet.2015.04.031 |
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title_sort |
immunological features of t cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma |
title_auth |
Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma |
abstract |
• The safety and immunogenicity of hTERT-derived peptide (hTERT461) as a peptide vaccine to hepatocellular carcinoma was confirmed. • The post-vaccinated increase in hTERT461 peptide-specific T cells was due to the increase in cells with the effector memory phenotype. • We showed the possible efficacy of hTERT-derived peptide vaccine in preventing HCC recurrence after curative treatments. • We also succeeded in obtaining the hTERT-specific T cell receptors from hTERT461 peptide-specific T cells. |
abstractGer |
• The safety and immunogenicity of hTERT-derived peptide (hTERT461) as a peptide vaccine to hepatocellular carcinoma was confirmed. • The post-vaccinated increase in hTERT461 peptide-specific T cells was due to the increase in cells with the effector memory phenotype. • We showed the possible efficacy of hTERT-derived peptide vaccine in preventing HCC recurrence after curative treatments. • We also succeeded in obtaining the hTERT-specific T cell receptors from hTERT461 peptide-specific T cells. |
abstract_unstemmed |
• The safety and immunogenicity of hTERT-derived peptide (hTERT461) as a peptide vaccine to hepatocellular carcinoma was confirmed. • The post-vaccinated increase in hTERT461 peptide-specific T cells was due to the increase in cells with the effector memory phenotype. • We showed the possible efficacy of hTERT-derived peptide vaccine in preventing HCC recurrence after curative treatments. • We also succeeded in obtaining the hTERT-specific T cell receptors from hTERT461 peptide-specific T cells. |
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title_short |
Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma |
url |
https://doi.org/10.1016/j.canlet.2015.04.031 |
remote_bool |
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author2 |
Nakagawa, Hidetoshi Kitahara, Masaaki Yamashita, Tatsuya Arai, Kuniaki Sunagozaka, Hajime Fushimi, Kazumi Kobayashi, Eiji Kishi, Hiroyuki Muraguchi, Atsushi Kaneko, Shuichi |
author2Str |
Nakagawa, Hidetoshi Kitahara, Masaaki Yamashita, Tatsuya Arai, Kuniaki Sunagozaka, Hajime Fushimi, Kazumi Kobayashi, Eiji Kishi, Hiroyuki Muraguchi, Atsushi Kaneko, Shuichi |
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doi_str |
10.1016/j.canlet.2015.04.031 |
up_date |
2024-07-06T19:03:49.615Z |
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