c-Met targeting in advanced gastric cancer: An open challenge
• Different compounds targeting c-Met have been developed and tested in gastric cancer. • Discouraging outcomes of anti-c-Met monoclonal antibodies has been recently underlined. • No clear anti-tumor activity was identified in small molecule c-Met inhibitors except for high c-Met-positive tumors. •...
Ausführliche Beschreibung
Autor*in: |
Marano, Luigi [verfasserIn] |
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Englisch |
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2015 |
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7 |
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Enthalten in: GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome - Hao, Lijun ELSEVIER, 2015, an international journal providing a forum for original and pertinent contributions in cancer research, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:365 ; year:2015 ; number:1 ; day:28 ; month:08 ; pages:30-36 ; extent:7 |
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DOI / URN: |
10.1016/j.canlet.2015.05.028 |
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ELV023514256 |
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10.1016/j.canlet.2015.05.028 doi GBVA2015010000010.pica (DE-627)ELV023514256 (ELSEVIER)S0304-3835(15)00378-X DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 600 690 VZ 51.00 bkl 51.32 bkl Marano, Luigi verfasserin aut c-Met targeting in advanced gastric cancer: An open challenge 2015 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Different compounds targeting c-Met have been developed and tested in gastric cancer. • Discouraging outcomes of anti-c-Met monoclonal antibodies has been recently underlined. • No clear anti-tumor activity was identified in small molecule c-Met inhibitors except for high c-Met-positive tumors. • Several biomarkers are being explored in order to clarify the question of potential treatment benefits in selected patients. Chiari, Rita oth Fabozzi, Alessio oth De Vita, Ferdinando oth Boccardi, Virginia oth Roviello, Giandomenico oth Petrioli, Roberto oth Marrelli, Daniele oth Roviello, Franco oth Patriti, Alberto oth Enthalten in Elsevier Science Hao, Lijun ELSEVIER GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome 2015 an international journal providing a forum for original and pertinent contributions in cancer research Amsterdam [u.a.] (DE-627)ELV013094742 volume:365 year:2015 number:1 day:28 month:08 pages:30-36 extent:7 https://doi.org/10.1016/j.canlet.2015.05.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_11 GBV_ILN_40 51.00 Werkstoffkunde: Allgemeines VZ 51.32 Werkstoffmechanik VZ AR 365 2015 1 28 0828 30-36 7 045F 570 |
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10.1016/j.canlet.2015.05.028 doi GBVA2015010000010.pica (DE-627)ELV023514256 (ELSEVIER)S0304-3835(15)00378-X DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 600 690 VZ 51.00 bkl 51.32 bkl Marano, Luigi verfasserin aut c-Met targeting in advanced gastric cancer: An open challenge 2015 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Different compounds targeting c-Met have been developed and tested in gastric cancer. • Discouraging outcomes of anti-c-Met monoclonal antibodies has been recently underlined. • No clear anti-tumor activity was identified in small molecule c-Met inhibitors except for high c-Met-positive tumors. • Several biomarkers are being explored in order to clarify the question of potential treatment benefits in selected patients. Chiari, Rita oth Fabozzi, Alessio oth De Vita, Ferdinando oth Boccardi, Virginia oth Roviello, Giandomenico oth Petrioli, Roberto oth Marrelli, Daniele oth Roviello, Franco oth Patriti, Alberto oth Enthalten in Elsevier Science Hao, Lijun ELSEVIER GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome 2015 an international journal providing a forum for original and pertinent contributions in cancer research Amsterdam [u.a.] (DE-627)ELV013094742 volume:365 year:2015 number:1 day:28 month:08 pages:30-36 extent:7 https://doi.org/10.1016/j.canlet.2015.05.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_11 GBV_ILN_40 51.00 Werkstoffkunde: Allgemeines VZ 51.32 Werkstoffmechanik VZ AR 365 2015 1 28 0828 30-36 7 045F 570 |
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10.1016/j.canlet.2015.05.028 doi GBVA2015010000010.pica (DE-627)ELV023514256 (ELSEVIER)S0304-3835(15)00378-X DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 600 690 VZ 51.00 bkl 51.32 bkl Marano, Luigi verfasserin aut c-Met targeting in advanced gastric cancer: An open challenge 2015 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Different compounds targeting c-Met have been developed and tested in gastric cancer. • Discouraging outcomes of anti-c-Met monoclonal antibodies has been recently underlined. • No clear anti-tumor activity was identified in small molecule c-Met inhibitors except for high c-Met-positive tumors. • Several biomarkers are being explored in order to clarify the question of potential treatment benefits in selected patients. Chiari, Rita oth Fabozzi, Alessio oth De Vita, Ferdinando oth Boccardi, Virginia oth Roviello, Giandomenico oth Petrioli, Roberto oth Marrelli, Daniele oth Roviello, Franco oth Patriti, Alberto oth Enthalten in Elsevier Science Hao, Lijun ELSEVIER GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome 2015 an international journal providing a forum for original and pertinent contributions in cancer research Amsterdam [u.a.] (DE-627)ELV013094742 volume:365 year:2015 number:1 day:28 month:08 pages:30-36 extent:7 https://doi.org/10.1016/j.canlet.2015.05.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_11 GBV_ILN_40 51.00 Werkstoffkunde: Allgemeines VZ 51.32 Werkstoffmechanik VZ AR 365 2015 1 28 0828 30-36 7 045F 570 |
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• Different compounds targeting c-Met have been developed and tested in gastric cancer. • Discouraging outcomes of anti-c-Met monoclonal antibodies has been recently underlined. • No clear anti-tumor activity was identified in small molecule c-Met inhibitors except for high c-Met-positive tumors. • Several biomarkers are being explored in order to clarify the question of potential treatment benefits in selected patients. |
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