Pleiotrophin modulates morphine withdrawal but has no effects on morphine-conditioned place preference
• We studied the effects of morphine in PTN genetically deficient (PTN−/−) mice. • PTN−/− didn’t show significant differences with WT in morphine rewarding effects. • Naloxone-precipitated morphine withdrawal was more severe in PTN−/− mice. • PTN is a novel genetic factor with a role in morphine wit...
Ausführliche Beschreibung
Autor*in: |
Gramage, Esther [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2015 |
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Schlagwörter: |
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Umfang: |
5 |
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Übergeordnetes Werk: |
Enthalten in: Faecal sludge containment characteristics and their implications on safe desludging in unplanned settlements of Dar es Salaam, Tanzania - Seleman, Amour ELSEVIER, 2021, an international multidisciplinary journal devoted to the rapid publication of basic research in the neurosciences, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:604 ; year:2015 ; day:14 ; month:09 ; pages:75-79 ; extent:5 |
Links: |
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DOI / URN: |
10.1016/j.neulet.2015.07.022 |
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ELV023539453 |
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• We studied the effects of morphine in PTN genetically deficient (PTN−/−) mice. • PTN−/− didn’t show significant differences with WT in morphine rewarding effects. • Naloxone-precipitated morphine withdrawal was more severe in PTN−/− mice. • PTN is a novel genetic factor with a role in morphine withdrawal. |
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• We studied the effects of morphine in PTN genetically deficient (PTN−/−) mice. • PTN−/− didn’t show significant differences with WT in morphine rewarding effects. • Naloxone-precipitated morphine withdrawal was more severe in PTN−/− mice. • PTN is a novel genetic factor with a role in morphine withdrawal. |
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• We studied the effects of morphine in PTN genetically deficient (PTN−/−) mice. • PTN−/− didn’t show significant differences with WT in morphine rewarding effects. • Naloxone-precipitated morphine withdrawal was more severe in PTN−/− mice. • PTN is a novel genetic factor with a role in morphine withdrawal. |
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