Improved DNA microarray detection sensitivity through immobilization of preformed in solution streptavidin/biotinylated oligonucleotide conjugates

Highlights • Immobilization approach based on biotinylated oligo/streptavidin conjugates. • Enhanced oligonucleotides immobilization efficiency and detection sensitivity. • Improved hybridization kinetics and discrimination ability of mutations. • Microarray for detection of seven most common BRCA1...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Mavrogiannopoulou, E. [verfasserIn]

Petrou, P.S.

Koukouvinos, G.

Yannoukakos, D.

Siafaka-Kapadai, A.

Fornal, K.

Awsiuk, K.

Budkowski, A.

Kakabakos, S.E.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2015

Schlagwörter:

Biotinylated oligonucleotides

Microarrays

BRCA1 gene mutations

Streptavidin

Oligonucleotide immobilization

Umfang:

9

Übergeordnetes Werk:

Enthalten in: Pharmacy students' perceptions toward peer assessment and its use in teaching patient presentation skills - Han, Zhe ELSEVIER, 2019, an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:128 ; year:2015 ; day:1 ; month:04 ; pages:464-472 ; extent:9

Links:

Volltext

DOI / URN:

10.1016/j.colsurfb.2015.02.045

Katalog-ID:

ELV023797630

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