6,7-Dihydrobenzo[f]benzo[4,5]imidazo[1,2-d][1,4]oxazepine derivatives as selective inhibitors of PI3Kα

Twenty eight new 6,7-dihydrobenzo[f]benzo[4,5]imidazo[1,2-d][1,4]oxazepine derivatives have been synthesized and evaluated for biological activities as PI3Kα inhibitors. Compound 25 showed the most potent inhibitory activity.

Gespeichert in:
Autor*in:

Yin, Yong [verfasserIn]

Zhang, Yan-Qing

Jin, Biao

Sha, Shao

Wu, Xun

Sangani, Chetan B.

Wang, She-Feng

Qiao, Fang

Lu, Ai-Min

Lv, Peng-Cheng

Zhu, Hai-Liang

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2015

Schlagwörter:

6,7-Dihydrobenzo[f]benzo[4,5]imidazo[1,2-d][1,4]oxazepine derivatives

Antitumor

PI3Kα

Umfang:

10

Übergeordnetes Werk:

Enthalten in: A theoretical model of cyberchondria development: Antecedents and intermediate processes - Zheng, Han ELSEVIER, 2021, a Tetrahedron publication for the rapid dissemination of full original research papers and critical reviews on bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:23 ; year:2015 ; number:6 ; day:15 ; month:03 ; pages:1231-1240 ; extent:10

Links:

Volltext

DOI / URN:

10.1016/j.bmc.2015.01.052

Katalog-ID:

ELV02382722X

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