Reactive oxygen species and c-Jun N-terminal kinases contribute to TEMPO-induced apoptosis in L5178Y cells
• TEMPO induced time- and concentration-dependent intracellular ROS production. • TEMPO increased caspase-3/7 activity and the proportion of annexin V stained cells. • TEMPO decreased expression of anti-apoptotic proteins (Bcl-2, Bcl-xL, and Mcl-1). • TEMPO activated c-Jun N-terminal kinases (JNK) i...
Ausführliche Beschreibung
Autor*in: |
Guo, Xiaoqing [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2015 |
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Schlagwörter: |
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Umfang: |
10 |
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Übergeordnetes Werk: |
Enthalten in: Ambiguous information and dilation: An experiment - Shishkin, Denis ELSEVIER, 2023, a journal of molecular and biochemical toxicology, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:235 ; year:2015 ; day:25 ; month:06 ; pages:27-36 ; extent:10 |
Links: |
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DOI / URN: |
10.1016/j.cbi.2015.04.009 |
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ELV023922702 |
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10.1016/j.cbi.2015.04.009 doi GBVA2015020000006.pica (DE-627)ELV023922702 (ELSEVIER)S0009-2797(15)00153-2 DE-627 ger DE-627 rakwb eng 570 540 570 DE-600 540 DE-600 330 VZ 31.00 bkl 83.10 bkl Guo, Xiaoqing verfasserin aut Reactive oxygen species and c-Jun N-terminal kinases contribute to TEMPO-induced apoptosis in L5178Y cells 2015 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • TEMPO induced time- and concentration-dependent intracellular ROS production. • TEMPO increased caspase-3/7 activity and the proportion of annexin V stained cells. • TEMPO decreased expression of anti-apoptotic proteins (Bcl-2, Bcl-xL, and Mcl-1). • TEMPO activated c-Jun N-terminal kinases (JNK) in the MAPK signaling pathway. MAPK pathway Elsevier Reactive oxygen species Elsevier TEMPO Elsevier Nitroxide Elsevier Apoptosis Elsevier Chen, Si oth Zhang, Zhuhong oth Dobrovolsky, Vasily N. oth Dial, Stacey L. oth Guo, Lei oth Mei, Nan oth Enthalten in Elsevier Science Shishkin, Denis ELSEVIER Ambiguous information and dilation: An experiment 2023 a journal of molecular and biochemical toxicology Amsterdam [u.a.] (DE-627)ELV009268340 volume:235 year:2015 day:25 month:06 pages:27-36 extent:10 https://doi.org/10.1016/j.cbi.2015.04.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-MAT 31.00 Mathematik: Allgemeines VZ 83.10 Wirtschaftstheorie: Allgemeines VZ AR 235 2015 25 0625 27-36 10 045F 570 |
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Reactive oxygen species and c-Jun N-terminal kinases contribute to TEMPO-induced apoptosis in L5178Y cells |
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• TEMPO induced time- and concentration-dependent intracellular ROS production. • TEMPO increased caspase-3/7 activity and the proportion of annexin V stained cells. • TEMPO decreased expression of anti-apoptotic proteins (Bcl-2, Bcl-xL, and Mcl-1). • TEMPO activated c-Jun N-terminal kinases (JNK) in the MAPK signaling pathway. |
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• TEMPO induced time- and concentration-dependent intracellular ROS production. • TEMPO increased caspase-3/7 activity and the proportion of annexin V stained cells. • TEMPO decreased expression of anti-apoptotic proteins (Bcl-2, Bcl-xL, and Mcl-1). • TEMPO activated c-Jun N-terminal kinases (JNK) in the MAPK signaling pathway. |
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• TEMPO induced time- and concentration-dependent intracellular ROS production. • TEMPO increased caspase-3/7 activity and the proportion of annexin V stained cells. • TEMPO decreased expression of anti-apoptotic proteins (Bcl-2, Bcl-xL, and Mcl-1). • TEMPO activated c-Jun N-terminal kinases (JNK) in the MAPK signaling pathway. |
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Reactive oxygen species and c-Jun N-terminal kinases contribute to TEMPO-induced apoptosis in L5178Y cells |
url |
https://doi.org/10.1016/j.cbi.2015.04.009 |
remote_bool |
true |
author2 |
Chen, Si Zhang, Zhuhong Dobrovolsky, Vasily N. Dial, Stacey L. Guo, Lei Mei, Nan |
author2Str |
Chen, Si Zhang, Zhuhong Dobrovolsky, Vasily N. Dial, Stacey L. Guo, Lei Mei, Nan |
ppnlink |
ELV009268340 |
mediatype_str_mv |
z |
isOA_txt |
false |
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author2_role |
oth oth oth oth oth oth |
doi_str |
10.1016/j.cbi.2015.04.009 |
up_date |
2024-07-06T20:04:24.095Z |
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1803861375419678720 |
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