Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis
Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called second-look surgeries, and intensified chemoradiotherapy. All previous studies assessing t...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Thompson, Eric M [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Umfang: |
12 |
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| Übergeordnetes Werk: |
Enthalten in: My - Citovsky, Vitaly ELSEVIER, 2019, London |
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| Übergeordnetes Werk: |
volume:17 ; year:2016 ; number:4 ; pages:484-495 ; extent:12 |
| Links: |
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| DOI / URN: |
10.1016/S1470-2045(15)00581-1 |
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ELV024207411 |
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| 245 | 1 | 0 | |a Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis |
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| 520 | |a Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called second-look surgeries, and intensified chemoradiotherapy. All previous studies assessing the clinical importance of extent of resection have not accounted for molecular subgroup. We analysed the prognostic value of extent of resection in a subgroup-specific manner. | ||
| 700 | 1 | |a Hielscher, Thomas |4 oth | |
| 700 | 1 | |a Bouffet, Eric |4 oth | |
| 700 | 1 | |a Remke, Marc |4 oth | |
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| 700 | 1 | |a Gururangan, Sridharan |4 oth | |
| 700 | 1 | |a McLendon, Roger E |4 oth | |
| 700 | 1 | |a Bigner, Darell D |4 oth | |
| 700 | 1 | |a Lipp, Eric S |4 oth | |
| 700 | 1 | |a Perreault, Sebastien |4 oth | |
| 700 | 1 | |a Cho, Yoon-Jae |4 oth | |
| 700 | 1 | |a Grant, Gerald |4 oth | |
| 700 | 1 | |a Kim, Seung-Ki |4 oth | |
| 700 | 1 | |a Lee, Ji Yeoun |4 oth | |
| 700 | 1 | |a Rao, Amulya A Nageswara |4 oth | |
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| 700 | 1 | |a Grajkowska, Wieslawa A |4 oth | |
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| 700 | 1 | |a Moore, Andrew S |4 oth | |
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10.1016/S1470-2045(15)00581-1 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001661.pica (DE-627)ELV024207411 (ELSEVIER)S1470-2045(15)00581-1 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Thompson, Eric M verfasserin aut Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis 2016 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called second-look surgeries, and intensified chemoradiotherapy. All previous studies assessing the clinical importance of extent of resection have not accounted for molecular subgroup. We analysed the prognostic value of extent of resection in a subgroup-specific manner. Hielscher, Thomas oth Bouffet, Eric oth Remke, Marc oth Luu, Betty oth Gururangan, Sridharan oth McLendon, Roger E oth Bigner, Darell D oth Lipp, Eric S oth Perreault, Sebastien oth Cho, Yoon-Jae oth Grant, Gerald oth Kim, Seung-Ki oth Lee, Ji Yeoun oth Rao, Amulya A Nageswara oth Giannini, Caterina oth Li, Kay Ka Wai oth Ng, Ho-Keung oth Yao, Yu oth Kumabe, Toshihiro oth Tominaga, Teiji oth Grajkowska, Wieslawa A oth Perek-Polnik, Marta oth Low, David C Y oth Seow, Wan Tew oth Chang, Kenneth T E oth Mora, Jaume oth Pollack, Ian F oth Hamilton, Ronald L oth Leary, Sarah oth Moore, Andrew S oth Ingram, Wendy J oth Hallahan, Andrew R oth Jouvet, Anne oth Fèvre-Montange, Michelle oth Vasiljevic, Alexandre oth Faure-Conter, Cecile oth Shofuda, Tomoko oth Kagawa, Naoki oth Hashimoto, Naoya oth Jabado, Nada oth Weil, Alexander G oth Gayden, Tenzin oth Wataya, Takafumi oth Shalaby, Tarek oth Grotzer, Michael oth Zitterbart, Karel oth Sterba, Jaroslav oth Kren, Leos oth Hortobágyi, Tibor oth Klekner, Almos oth László, Bognár oth Pócza, Tímea oth Hauser, Peter oth Schüller, Ulrich oth Jung, Shin oth Jang, Woo-Youl oth French, Pim J oth Kros, Johan M oth van Veelen, Marie-Lise C oth Massimi, Luca oth Leonard, Jeffrey R oth Rubin, Joshua B oth Vibhakar, Rajeev oth Chambless, Lola B oth Cooper, Michael K oth Thompson, Reid C oth Faria, Claudia C oth Carvalho, Alice oth Nunes, Sofia oth Pimentel, José oth Fan, Xing oth Muraszko, Karin M oth López-Aguilar, Enrique oth Lyden, David oth Garzia, Livia oth Shih, David J H oth Kijima, Noriyuki oth Schneider, Christian oth Adamski, Jennifer oth Northcott, Paul A oth Kool, Marcel oth Jones, David T W oth Chan, Jennifer A oth Nikolic, Ana oth Garre, Maria Luisa oth Van Meir, Erwin G oth Osuka, Satoru oth Olson, Jeffrey J oth Jahangiri, Arman oth Castro, Brandyn A oth Gupta, Nalin oth Weiss, William A oth Moxon-Emre, Iska oth Mabbott, Donald J oth Lassaletta, Alvaro oth Hawkins, Cynthia E oth Tabori, Uri oth Drake, James oth Kulkarni, Abhaya oth Dirks, Peter oth Rutka, James T oth Korshunov, Andrey oth Pfister, Stefan M oth Packer, Roger J oth Ramaswamy, Vijay oth Taylor, Michael D oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:17 year:2016 number:4 pages:484-495 extent:12 https://doi.org/10.1016/S1470-2045(15)00581-1 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 17 2016 4 484-495 12 |
| spelling |
10.1016/S1470-2045(15)00581-1 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001661.pica (DE-627)ELV024207411 (ELSEVIER)S1470-2045(15)00581-1 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Thompson, Eric M verfasserin aut Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis 2016 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called second-look surgeries, and intensified chemoradiotherapy. All previous studies assessing the clinical importance of extent of resection have not accounted for molecular subgroup. We analysed the prognostic value of extent of resection in a subgroup-specific manner. Hielscher, Thomas oth Bouffet, Eric oth Remke, Marc oth Luu, Betty oth Gururangan, Sridharan oth McLendon, Roger E oth Bigner, Darell D oth Lipp, Eric S oth Perreault, Sebastien oth Cho, Yoon-Jae oth Grant, Gerald oth Kim, Seung-Ki oth Lee, Ji Yeoun oth Rao, Amulya A Nageswara oth Giannini, Caterina oth Li, Kay Ka Wai oth Ng, Ho-Keung oth Yao, Yu oth Kumabe, Toshihiro oth Tominaga, Teiji oth Grajkowska, Wieslawa A oth Perek-Polnik, Marta oth Low, David C Y oth Seow, Wan Tew oth Chang, Kenneth T E oth Mora, Jaume oth Pollack, Ian F oth Hamilton, Ronald L oth Leary, Sarah oth Moore, Andrew S oth Ingram, Wendy J oth Hallahan, Andrew R oth Jouvet, Anne oth Fèvre-Montange, Michelle oth Vasiljevic, Alexandre oth Faure-Conter, Cecile oth Shofuda, Tomoko oth Kagawa, Naoki oth Hashimoto, Naoya oth Jabado, Nada oth Weil, Alexander G oth Gayden, Tenzin oth Wataya, Takafumi oth Shalaby, Tarek oth Grotzer, Michael oth Zitterbart, Karel oth Sterba, Jaroslav oth Kren, Leos oth Hortobágyi, Tibor oth Klekner, Almos oth László, Bognár oth Pócza, Tímea oth Hauser, Peter oth Schüller, Ulrich oth Jung, Shin oth Jang, Woo-Youl oth French, Pim J oth Kros, Johan M oth van Veelen, Marie-Lise C oth Massimi, Luca oth Leonard, Jeffrey R oth Rubin, Joshua B oth Vibhakar, Rajeev oth Chambless, Lola B oth Cooper, Michael K oth Thompson, Reid C oth Faria, Claudia C oth Carvalho, Alice oth Nunes, Sofia oth Pimentel, José oth Fan, Xing oth Muraszko, Karin M oth López-Aguilar, Enrique oth Lyden, David oth Garzia, Livia oth Shih, David J H oth Kijima, Noriyuki oth Schneider, Christian oth Adamski, Jennifer oth Northcott, Paul A oth Kool, Marcel oth Jones, David T W oth Chan, Jennifer A oth Nikolic, Ana oth Garre, Maria Luisa oth Van Meir, Erwin G oth Osuka, Satoru oth Olson, Jeffrey J oth Jahangiri, Arman oth Castro, Brandyn A oth Gupta, Nalin oth Weiss, William A oth Moxon-Emre, Iska oth Mabbott, Donald J oth Lassaletta, Alvaro oth Hawkins, Cynthia E oth Tabori, Uri oth Drake, James oth Kulkarni, Abhaya oth Dirks, Peter oth Rutka, James T oth Korshunov, Andrey oth Pfister, Stefan M oth Packer, Roger J oth Ramaswamy, Vijay oth Taylor, Michael D oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:17 year:2016 number:4 pages:484-495 extent:12 https://doi.org/10.1016/S1470-2045(15)00581-1 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 17 2016 4 484-495 12 |
| allfields_unstemmed |
10.1016/S1470-2045(15)00581-1 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001661.pica (DE-627)ELV024207411 (ELSEVIER)S1470-2045(15)00581-1 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Thompson, Eric M verfasserin aut Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis 2016 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called second-look surgeries, and intensified chemoradiotherapy. All previous studies assessing the clinical importance of extent of resection have not accounted for molecular subgroup. We analysed the prognostic value of extent of resection in a subgroup-specific manner. Hielscher, Thomas oth Bouffet, Eric oth Remke, Marc oth Luu, Betty oth Gururangan, Sridharan oth McLendon, Roger E oth Bigner, Darell D oth Lipp, Eric S oth Perreault, Sebastien oth Cho, Yoon-Jae oth Grant, Gerald oth Kim, Seung-Ki oth Lee, Ji Yeoun oth Rao, Amulya A Nageswara oth Giannini, Caterina oth Li, Kay Ka Wai oth Ng, Ho-Keung oth Yao, Yu oth Kumabe, Toshihiro oth Tominaga, Teiji oth Grajkowska, Wieslawa A oth Perek-Polnik, Marta oth Low, David C Y oth Seow, Wan Tew oth Chang, Kenneth T E oth Mora, Jaume oth Pollack, Ian F oth Hamilton, Ronald L oth Leary, Sarah oth Moore, Andrew S oth Ingram, Wendy J oth Hallahan, Andrew R oth Jouvet, Anne oth Fèvre-Montange, Michelle oth Vasiljevic, Alexandre oth Faure-Conter, Cecile oth Shofuda, Tomoko oth Kagawa, Naoki oth Hashimoto, Naoya oth Jabado, Nada oth Weil, Alexander G oth Gayden, Tenzin oth Wataya, Takafumi oth Shalaby, Tarek oth Grotzer, Michael oth Zitterbart, Karel oth Sterba, Jaroslav oth Kren, Leos oth Hortobágyi, Tibor oth Klekner, Almos oth László, Bognár oth Pócza, Tímea oth Hauser, Peter oth Schüller, Ulrich oth Jung, Shin oth Jang, Woo-Youl oth French, Pim J oth Kros, Johan M oth van Veelen, Marie-Lise C oth Massimi, Luca oth Leonard, Jeffrey R oth Rubin, Joshua B oth Vibhakar, Rajeev oth Chambless, Lola B oth Cooper, Michael K oth Thompson, Reid C oth Faria, Claudia C oth Carvalho, Alice oth Nunes, Sofia oth Pimentel, José oth Fan, Xing oth Muraszko, Karin M oth López-Aguilar, Enrique oth Lyden, David oth Garzia, Livia oth Shih, David J H oth Kijima, Noriyuki oth Schneider, Christian oth Adamski, Jennifer oth Northcott, Paul A oth Kool, Marcel oth Jones, David T W oth Chan, Jennifer A oth Nikolic, Ana oth Garre, Maria Luisa oth Van Meir, Erwin G oth Osuka, Satoru oth Olson, Jeffrey J oth Jahangiri, Arman oth Castro, Brandyn A oth Gupta, Nalin oth Weiss, William A oth Moxon-Emre, Iska oth Mabbott, Donald J oth Lassaletta, Alvaro oth Hawkins, Cynthia E oth Tabori, Uri oth Drake, James oth Kulkarni, Abhaya oth Dirks, Peter oth Rutka, James T oth Korshunov, Andrey oth Pfister, Stefan M oth Packer, Roger J oth Ramaswamy, Vijay oth Taylor, Michael D oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:17 year:2016 number:4 pages:484-495 extent:12 https://doi.org/10.1016/S1470-2045(15)00581-1 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 17 2016 4 484-495 12 |
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10.1016/S1470-2045(15)00581-1 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001661.pica (DE-627)ELV024207411 (ELSEVIER)S1470-2045(15)00581-1 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Thompson, Eric M verfasserin aut Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis 2016 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called second-look surgeries, and intensified chemoradiotherapy. All previous studies assessing the clinical importance of extent of resection have not accounted for molecular subgroup. We analysed the prognostic value of extent of resection in a subgroup-specific manner. Hielscher, Thomas oth Bouffet, Eric oth Remke, Marc oth Luu, Betty oth Gururangan, Sridharan oth McLendon, Roger E oth Bigner, Darell D oth Lipp, Eric S oth Perreault, Sebastien oth Cho, Yoon-Jae oth Grant, Gerald oth Kim, Seung-Ki oth Lee, Ji Yeoun oth Rao, Amulya A Nageswara oth Giannini, Caterina oth Li, Kay Ka Wai oth Ng, Ho-Keung oth Yao, Yu oth Kumabe, Toshihiro oth Tominaga, Teiji oth Grajkowska, Wieslawa A oth Perek-Polnik, Marta oth Low, David C Y oth Seow, Wan Tew oth Chang, Kenneth T E oth Mora, Jaume oth Pollack, Ian F oth Hamilton, Ronald L oth Leary, Sarah oth Moore, Andrew S oth Ingram, Wendy J oth Hallahan, Andrew R oth Jouvet, Anne oth Fèvre-Montange, Michelle oth Vasiljevic, Alexandre oth Faure-Conter, Cecile oth Shofuda, Tomoko oth Kagawa, Naoki oth Hashimoto, Naoya oth Jabado, Nada oth Weil, Alexander G oth Gayden, Tenzin oth Wataya, Takafumi oth Shalaby, Tarek oth Grotzer, Michael oth Zitterbart, Karel oth Sterba, Jaroslav oth Kren, Leos oth Hortobágyi, Tibor oth Klekner, Almos oth László, Bognár oth Pócza, Tímea oth Hauser, Peter oth Schüller, Ulrich oth Jung, Shin oth Jang, Woo-Youl oth French, Pim J oth Kros, Johan M oth van Veelen, Marie-Lise C oth Massimi, Luca oth Leonard, Jeffrey R oth Rubin, Joshua B oth Vibhakar, Rajeev oth Chambless, Lola B oth Cooper, Michael K oth Thompson, Reid C oth Faria, Claudia C oth Carvalho, Alice oth Nunes, Sofia oth Pimentel, José oth Fan, Xing oth Muraszko, Karin M oth López-Aguilar, Enrique oth Lyden, David oth Garzia, Livia oth Shih, David J H oth Kijima, Noriyuki oth Schneider, Christian oth Adamski, Jennifer oth Northcott, Paul A oth Kool, Marcel oth Jones, David T W oth Chan, Jennifer A oth Nikolic, Ana oth Garre, Maria Luisa oth Van Meir, Erwin G oth Osuka, Satoru oth Olson, Jeffrey J oth Jahangiri, Arman oth Castro, Brandyn A oth Gupta, Nalin oth Weiss, William A oth Moxon-Emre, Iska oth Mabbott, Donald J oth Lassaletta, Alvaro oth Hawkins, Cynthia E oth Tabori, Uri oth Drake, James oth Kulkarni, Abhaya oth Dirks, Peter oth Rutka, James T oth Korshunov, Andrey oth Pfister, Stefan M oth Packer, Roger J oth Ramaswamy, Vijay oth Taylor, Michael D oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:17 year:2016 number:4 pages:484-495 extent:12 https://doi.org/10.1016/S1470-2045(15)00581-1 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 17 2016 4 484-495 12 |
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Thompson, Eric M @@aut@@ Hielscher, Thomas @@oth@@ Bouffet, Eric @@oth@@ Remke, Marc @@oth@@ Luu, Betty @@oth@@ Gururangan, Sridharan @@oth@@ McLendon, Roger E @@oth@@ Bigner, Darell D @@oth@@ Lipp, Eric S @@oth@@ Perreault, Sebastien @@oth@@ Cho, Yoon-Jae @@oth@@ Grant, Gerald @@oth@@ Kim, Seung-Ki @@oth@@ Lee, Ji Yeoun @@oth@@ Rao, Amulya A Nageswara @@oth@@ Giannini, Caterina @@oth@@ Li, Kay Ka Wai @@oth@@ Ng, Ho-Keung @@oth@@ Yao, Yu @@oth@@ Kumabe, Toshihiro @@oth@@ Tominaga, Teiji @@oth@@ Grajkowska, Wieslawa A @@oth@@ Perek-Polnik, Marta @@oth@@ Low, David C Y @@oth@@ Seow, Wan Tew @@oth@@ Chang, Kenneth T E @@oth@@ Mora, Jaume @@oth@@ Pollack, Ian F @@oth@@ Hamilton, Ronald L @@oth@@ Leary, Sarah @@oth@@ Moore, Andrew S @@oth@@ Ingram, Wendy J @@oth@@ Hallahan, Andrew R @@oth@@ Jouvet, Anne @@oth@@ Fèvre-Montange, Michelle @@oth@@ Vasiljevic, Alexandre @@oth@@ Faure-Conter, Cecile @@oth@@ Shofuda, Tomoko @@oth@@ Kagawa, Naoki @@oth@@ Hashimoto, Naoya @@oth@@ Jabado, Nada @@oth@@ Weil, Alexander G @@oth@@ Gayden, Tenzin @@oth@@ Wataya, Takafumi @@oth@@ Shalaby, Tarek @@oth@@ Grotzer, Michael @@oth@@ Zitterbart, Karel @@oth@@ Sterba, Jaroslav @@oth@@ Kren, Leos @@oth@@ Hortobágyi, Tibor @@oth@@ Klekner, Almos @@oth@@ László, Bognár @@oth@@ Pócza, Tímea @@oth@@ Hauser, Peter @@oth@@ Schüller, Ulrich @@oth@@ Jung, Shin @@oth@@ Jang, Woo-Youl @@oth@@ French, Pim J @@oth@@ Kros, Johan M @@oth@@ van Veelen, Marie-Lise C @@oth@@ Massimi, Luca @@oth@@ Leonard, Jeffrey R @@oth@@ Rubin, Joshua B @@oth@@ Vibhakar, Rajeev @@oth@@ Chambless, Lola B @@oth@@ Cooper, Michael K @@oth@@ Thompson, Reid C @@oth@@ Faria, Claudia C @@oth@@ Carvalho, Alice @@oth@@ Nunes, Sofia @@oth@@ Pimentel, José @@oth@@ Fan, Xing @@oth@@ Muraszko, Karin M @@oth@@ López-Aguilar, Enrique @@oth@@ Lyden, David @@oth@@ Garzia, Livia @@oth@@ Shih, David J H @@oth@@ Kijima, Noriyuki @@oth@@ Schneider, Christian @@oth@@ Adamski, Jennifer @@oth@@ Northcott, Paul A @@oth@@ Kool, Marcel @@oth@@ Jones, David T W @@oth@@ Chan, Jennifer A @@oth@@ Nikolic, Ana @@oth@@ Garre, Maria Luisa @@oth@@ Van Meir, Erwin G @@oth@@ Osuka, Satoru @@oth@@ Olson, Jeffrey J @@oth@@ Jahangiri, Arman @@oth@@ Castro, Brandyn A @@oth@@ Gupta, Nalin @@oth@@ Weiss, William A @@oth@@ Moxon-Emre, Iska @@oth@@ Mabbott, Donald J @@oth@@ Lassaletta, Alvaro @@oth@@ Hawkins, Cynthia E @@oth@@ Tabori, Uri @@oth@@ Drake, James @@oth@@ Kulkarni, Abhaya @@oth@@ Dirks, Peter @@oth@@ Rutka, James T @@oth@@ Korshunov, Andrey @@oth@@ Pfister, Stefan M @@oth@@ Packer, Roger J @@oth@@ Ramaswamy, Vijay @@oth@@ Taylor, Michael D @@oth@@ |
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prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis |
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Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis |
| abstract |
Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called second-look surgeries, and intensified chemoradiotherapy. All previous studies assessing the clinical importance of extent of resection have not accounted for molecular subgroup. We analysed the prognostic value of extent of resection in a subgroup-specific manner. |
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Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called second-look surgeries, and intensified chemoradiotherapy. All previous studies assessing the clinical importance of extent of resection have not accounted for molecular subgroup. We analysed the prognostic value of extent of resection in a subgroup-specific manner. |
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Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called second-look surgeries, and intensified chemoradiotherapy. All previous studies assessing the clinical importance of extent of resection have not accounted for molecular subgroup. We analysed the prognostic value of extent of resection in a subgroup-specific manner. |
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Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis |
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