Use of basic mobile phase to improve chromatography and boost sensitivity for quantifying tetrahydrocurcumin in human plasma by LC–MS/MS
• Tetrahydrocurcumin was separated by using a basic mobile phase for the first time. • Split or poor chromatographic peaks were avoided by using the basic mobile phase. • Seven-fold higher sensitivity obtained with the basic mobile phase than an acidic one. • Short residence on LC column may not cau...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Tan, Aimin [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Umfang: |
8 |
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| Übergeordnetes Werk: |
Enthalten in: Brain microstructure and morphology of very preterm-born infants at term equivalent age: Associations with motor and cognitive outcomes at 1 and 2 years - Pannek, Kerstin ELSEVIER, 2020, New York, NY [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:1028 ; year:2016 ; day:15 ; month:08 ; pages:86-93 ; extent:8 |
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| DOI / URN: |
10.1016/j.jchromb.2016.06.010 |
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| 520 | |a • Tetrahydrocurcumin was separated by using a basic mobile phase for the first time. • Split or poor chromatographic peaks were avoided by using the basic mobile phase. • Seven-fold higher sensitivity obtained with the basic mobile phase than an acidic one. • Short residence on LC column may not cause notable degradation of unstable analytes. • The unconventional approach used here is generally applicable to similar situations. | ||
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| title_sort |
use of basic mobile phase to improve chromatography and boost sensitivity for quantifying tetrahydrocurcumin in human plasma by lc–ms/ms |
| title_auth |
Use of basic mobile phase to improve chromatography and boost sensitivity for quantifying tetrahydrocurcumin in human plasma by LC–MS/MS |
| abstract |
• Tetrahydrocurcumin was separated by using a basic mobile phase for the first time. • Split or poor chromatographic peaks were avoided by using the basic mobile phase. • Seven-fold higher sensitivity obtained with the basic mobile phase than an acidic one. • Short residence on LC column may not cause notable degradation of unstable analytes. • The unconventional approach used here is generally applicable to similar situations. |
| abstractGer |
• Tetrahydrocurcumin was separated by using a basic mobile phase for the first time. • Split or poor chromatographic peaks were avoided by using the basic mobile phase. • Seven-fold higher sensitivity obtained with the basic mobile phase than an acidic one. • Short residence on LC column may not cause notable degradation of unstable analytes. • The unconventional approach used here is generally applicable to similar situations. |
| abstract_unstemmed |
• Tetrahydrocurcumin was separated by using a basic mobile phase for the first time. • Split or poor chromatographic peaks were avoided by using the basic mobile phase. • Seven-fold higher sensitivity obtained with the basic mobile phase than an acidic one. • Short residence on LC column may not cause notable degradation of unstable analytes. • The unconventional approach used here is generally applicable to similar situations. |
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| title_short |
Use of basic mobile phase to improve chromatography and boost sensitivity for quantifying tetrahydrocurcumin in human plasma by LC–MS/MS |
| url |
https://doi.org/10.1016/j.jchromb.2016.06.010 |
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Wu, Yanxin Wong, Molly Licollari, Albert Bolger, Gordon Fanaras, John C. Shopp, George Helson, Lawrence |
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Wu, Yanxin Wong, Molly Licollari, Albert Bolger, Gordon Fanaras, John C. Shopp, George Helson, Lawrence |
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