Randomized placebo-controlled trial of sodium valproate in progressive supranuclear palsy

• Inhibition of glycogen synthase kinase (GSK-3) is a therapeutic option for PSP. • We assessed the safety and efficacy of sodium valproate (VPA), a GSK-3 inhibitor, in PSP. • VPA was not effective as a disease-modifying agent in PSP.

Gespeichert in:
Autor*in:

Leclair-Visonneau, Laurène [verfasserIn]

Rouaud, Tiphaine

Debilly, Bérangère

Durif, Franck

Houeto, Jean-Luc

Kreisler, Alexandre

Defebvre, Luc

Lamy, Estelle

Volteau, Christelle

Nguyen, Jean-Michel

Dily, Séverine Le

Damier, Philippe

Boutoleau-Bretonnière, Claire

Lejeune, Pascal

Derkinderen, Pascal

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2016

Schlagwörter:

Neuroprotection

Controlled-trial

Progressive supranuclear palsy

Sodium valproate

Umfang:

5

Übergeordnetes Werk:

Enthalten in: SUDDEN CARDIAC DEATH IN MALIGNANT BILEAFLET MITRAL VALVE PROLAPSE - Kanuri, Swapna ELSEVIER, 2015, official publication of the Netherlands Society of Neurology and the Netherlands Society of Neurosurgery and the Flemish Society of Neurology, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:146 ; year:2016 ; pages:35-39 ; extent:5

Links:

Volltext

DOI / URN:

10.1016/j.clineuro.2016.04.021

Katalog-ID:

ELV024436097

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