A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion
• BM-MCSs increase proliferation, migration and invasion in osteosarcoma (OS) and hepatocellular carcinoma (HCC) cell lines. • BM-MCSs activate the AKT and ERK pathways in OS and HCC cells. • CXCR4 plays a key role in the cross-talk between BM-MCSs and tumor cells. • A novel CXCR4 antagonist prevent...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Fontanella, Raffaela [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Umfang: |
8 |
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| Übergeordnetes Werk: |
Enthalten in: GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome - Hao, Lijun ELSEVIER, 2015, an international journal providing a forum for original and pertinent contributions in cancer research, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:370 ; year:2016 ; number:1 ; day:1 ; month:01 ; pages:100-107 ; extent:8 |
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10.1016/j.canlet.2015.10.018 |
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A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion |
| abstract |
• BM-MCSs increase proliferation, migration and invasion in osteosarcoma (OS) and hepatocellular carcinoma (HCC) cell lines. • BM-MCSs activate the AKT and ERK pathways in OS and HCC cells. • CXCR4 plays a key role in the cross-talk between BM-MCSs and tumor cells. • A novel CXCR4 antagonist prevents BM-MSC-mediated OS and HCC progression. |
| abstractGer |
• BM-MCSs increase proliferation, migration and invasion in osteosarcoma (OS) and hepatocellular carcinoma (HCC) cell lines. • BM-MCSs activate the AKT and ERK pathways in OS and HCC cells. • CXCR4 plays a key role in the cross-talk between BM-MCSs and tumor cells. • A novel CXCR4 antagonist prevents BM-MSC-mediated OS and HCC progression. |
| abstract_unstemmed |
• BM-MCSs increase proliferation, migration and invasion in osteosarcoma (OS) and hepatocellular carcinoma (HCC) cell lines. • BM-MCSs activate the AKT and ERK pathways in OS and HCC cells. • CXCR4 plays a key role in the cross-talk between BM-MCSs and tumor cells. • A novel CXCR4 antagonist prevents BM-MSC-mediated OS and HCC progression. |
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| title_short |
A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion |
| url |
https://doi.org/10.1016/j.canlet.2015.10.018 |
| remote_bool |
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| author2 |
Pelagalli, Alessandra Nardelli, Anna D'Alterio, Crescenzo Ieranò, Caterina Cerchia, Laura Lucarelli, Enrico Scala, Stefania Zannetti, Antonella |
| author2Str |
Pelagalli, Alessandra Nardelli, Anna D'Alterio, Crescenzo Ieranò, Caterina Cerchia, Laura Lucarelli, Enrico Scala, Stefania Zannetti, Antonella |
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| doi_str |
10.1016/j.canlet.2015.10.018 |
| up_date |
2024-07-06T21:26:49.272Z |
| _version_ |
1803866560814645248 |
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