Generation and characterization of an induced pluripotent stem cell (iPSC) line from a patient with clozapine-resistant Schizophrenia
Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Marsoner, Fabio [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2016transfer abstract |
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| Umfang: |
4 |
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| Übergeordnetes Werk: |
Enthalten in: Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study - Hamood, Rola ELSEVIER, 2018, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:17 ; year:2016 ; number:3 ; pages:661-664 ; extent:4 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.scr.2016.11.005 |
|---|
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ELV024463116 |
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| 520 | |a Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. | ||
| 520 | |a Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. | ||
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| 700 | 1 | |a Karnavas, Thodoris |4 oth | |
| 700 | 1 | |a Bottai, Daniele |4 oth | |
| 700 | 1 | |a D'Agostino, Armando |4 oth | |
| 700 | 1 | |a Scarone, Silvio |4 oth | |
| 700 | 1 | |a Conti, Luciano |4 oth | |
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10.1016/j.scr.2016.11.005 doi GBVA2016011000002.pica (DE-627)ELV024463116 (ELSEVIER)S1873-5061(16)30177-5 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 44.85 bkl Marsoner, Fabio verfasserin aut Generation and characterization of an induced pluripotent stem cell (iPSC) line from a patient with clozapine-resistant Schizophrenia 2016transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. Marcatili, Matteo oth Karnavas, Thodoris oth Bottai, Daniele oth D'Agostino, Armando oth Scarone, Silvio oth Conti, Luciano oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:17 year:2016 number:3 pages:661-664 extent:4 https://doi.org/10.1016/j.scr.2016.11.005 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 17 2016 3 661-664 4 045F 570 |
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10.1016/j.scr.2016.11.005 doi GBVA2016011000002.pica (DE-627)ELV024463116 (ELSEVIER)S1873-5061(16)30177-5 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 44.85 bkl Marsoner, Fabio verfasserin aut Generation and characterization of an induced pluripotent stem cell (iPSC) line from a patient with clozapine-resistant Schizophrenia 2016transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. Marcatili, Matteo oth Karnavas, Thodoris oth Bottai, Daniele oth D'Agostino, Armando oth Scarone, Silvio oth Conti, Luciano oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:17 year:2016 number:3 pages:661-664 extent:4 https://doi.org/10.1016/j.scr.2016.11.005 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 17 2016 3 661-664 4 045F 570 |
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10.1016/j.scr.2016.11.005 doi GBVA2016011000002.pica (DE-627)ELV024463116 (ELSEVIER)S1873-5061(16)30177-5 DE-627 ger DE-627 rakwb eng 570 570 DE-600 610 VZ 44.85 bkl Marsoner, Fabio verfasserin aut Generation and characterization of an induced pluripotent stem cell (iPSC) line from a patient with clozapine-resistant Schizophrenia 2016transfer abstract 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. Marcatili, Matteo oth Karnavas, Thodoris oth Bottai, Daniele oth D'Agostino, Armando oth Scarone, Silvio oth Conti, Luciano oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:17 year:2016 number:3 pages:661-664 extent:4 https://doi.org/10.1016/j.scr.2016.11.005 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 17 2016 3 661-664 4 045F 570 |
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Enthalten in Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study Amsterdam [u.a.] volume:17 year:2016 number:3 pages:661-664 extent:4 |
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Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study |
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Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study |
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Marsoner, Fabio |
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generation and characterization of an induced pluripotent stem cell (ipsc) line from a patient with clozapine-resistant schizophrenia |
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Generation and characterization of an induced pluripotent stem cell (iPSC) line from a patient with clozapine-resistant Schizophrenia |
| abstract |
Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. |
| abstractGer |
Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. |
| abstract_unstemmed |
Peripheral Blood Mononuclear Cells (PBMCs) were collected from a patient with clozapine-resistant (also known as “super-refractory”) Schizophrenia. iPSCs were established with a non-integrating Sendai virus-based reprogramming system. A footprint-free hiPSC line was characterized to express the main endogenous pluripotency markers and to retain a normal karyotype. Cells showed pluripotency competency by giving rise to progeny of differentiated cells belonging to the three germ layers. This hiPSC line represents a valuable tool to obtain mature, pathology-relevant neuronal populations in vitro that are suitable to investigate the molecular background of the schizophrenic disorder and the resultant patients' response to treatments. |
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Generation and characterization of an induced pluripotent stem cell (iPSC) line from a patient with clozapine-resistant Schizophrenia |
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Marcatili, Matteo Karnavas, Thodoris Bottai, Daniele D'Agostino, Armando Scarone, Silvio Conti, Luciano |
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Marcatili, Matteo Karnavas, Thodoris Bottai, Daniele D'Agostino, Armando Scarone, Silvio Conti, Luciano |
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