Combined immunotherapy: CTLA-4 blockade potentiates anti-tumor response induced by transcutaneous immunization
• Check point blockade of CTLA-4 augments TCI mediated T-cell responses and supports memory formation. • Combined immunotherapy with TCI and CTLA-4 blockade improves survival of mice with B16 OVA melanoma. • In TCI, enhanced T-cell responses by CTLA-4 blockade are mainly independent of Treg cells....
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Rausch, Johanna [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2017 |
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| Schlagwörter: |
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| Umfang: |
7 |
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| Übergeordnetes Werk: |
Enthalten in: Acceptability of a smartphone application with prenatal care at a federally qualified health center - Vani, Kavita ELSEVIER, 2022, the official journal of the Japanese Society for Investigative Dermatology, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:87 ; year:2017 ; number:3 ; pages:300-306 ; extent:7 |
| Links: |
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| DOI / URN: |
10.1016/j.jdermsci.2017.06.013 |
|---|
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ELV025372955 |
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• Check point blockade of CTLA-4 augments TCI mediated T-cell responses and supports memory formation. • Combined immunotherapy with TCI and CTLA-4 blockade improves survival of mice with B16 OVA melanoma. • In TCI, enhanced T-cell responses by CTLA-4 blockade are mainly independent of Treg cells. |
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• Check point blockade of CTLA-4 augments TCI mediated T-cell responses and supports memory formation. • Combined immunotherapy with TCI and CTLA-4 blockade improves survival of mice with B16 OVA melanoma. • In TCI, enhanced T-cell responses by CTLA-4 blockade are mainly independent of Treg cells. |
| abstract_unstemmed |
• Check point blockade of CTLA-4 augments TCI mediated T-cell responses and supports memory formation. • Combined immunotherapy with TCI and CTLA-4 blockade improves survival of mice with B16 OVA melanoma. • In TCI, enhanced T-cell responses by CTLA-4 blockade are mainly independent of Treg cells. |
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| title_short |
Combined immunotherapy: CTLA-4 blockade potentiates anti-tumor response induced by transcutaneous immunization |
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https://doi.org/10.1016/j.jdermsci.2017.06.013 |
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Lopez, Pamela Aranda Bialojan, Ariane Denny, Mark Langguth, Peter Probst, Hans Christian Schild, Hansjörg Radsak, Markus P. |
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Lopez, Pamela Aranda Bialojan, Ariane Denny, Mark Langguth, Peter Probst, Hans Christian Schild, Hansjörg Radsak, Markus P. |
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10.1016/j.jdermsci.2017.06.013 |
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