Downregulation of the polyamine regulator spermidine/spermine N1-acetyltransferase by Epstein–Barr virus in a Burkitt's lymphoma cell line

• EBV-positive Akata BL demonstrated reduced SAT1 mRNA levels. • EBV-positive Akata BL showed altered SAT1 enzyme activity and polyamine levels. • Reduction of SAT1 in EBV-positive Akata BL occurred at the level of transcription. • Forced expression of the EBV BCL2 homolog, BHRF1, reduced SAT1 mRNA...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Shi, Mingxia [verfasserIn]

Gan, Yan-jun

Davis, Timothy O.

Scott, Rona S.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2013

Schlagwörter:

Akata

c-myc

EBV

Spermidine/spermine N1-acetyltransferase

Polyamines

Burkitt's lymphoma

Umfang:

11

Übergeordnetes Werk:

Enthalten in: AKT-mediated enhanced aerobic glycolysis causes acquired radioresistance by human tumor cells - Shimura, Tsutomu ELSEVIER, 2014, an international journal of molecular and cellular virology, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:177 ; year:2013 ; number:1 ; pages:11-21 ; extent:11

Links:

Volltext

DOI / URN:

10.1016/j.virusres.2013.07.004

Katalog-ID:

ELV027098486

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