MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways
• miR-21 suppresses the expression of hSulf-1 and PTEN in HCC cells. • Suppression of hSulf-1 or PTEN by miR-21 can activate AKT/ERK1/2 signaling. • Activation of AKT/ERK1/2 pathways induces EMT in HCC cells. • miR-21 functions to promote cancer cell proliferation and movement.
Gespeichert in:
| Autor*in: |
Bao, Longlong [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2013 |
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11 |
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| Übergeordnetes Werk: |
Enthalten in: GW26-e0273 Relationship between thrombelastography test and routine platelet parameters in patients with acute coronary syndrome - Hao, Lijun ELSEVIER, 2015, an international journal providing a forum for original and pertinent contributions in cancer research, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:337 ; year:2013 ; number:2 ; day:1 ; month:09 ; pages:226-236 ; extent:11 |
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|---|
| DOI / URN: |
10.1016/j.canlet.2013.05.007 |
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MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways |
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MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways |
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microrna-21 suppresses pten and hsulf-1 expression and promotes hepatocellular carcinoma progression through akt/erk pathways |
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MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways |
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• miR-21 suppresses the expression of hSulf-1 and PTEN in HCC cells. • Suppression of hSulf-1 or PTEN by miR-21 can activate AKT/ERK1/2 signaling. • Activation of AKT/ERK1/2 pathways induces EMT in HCC cells. • miR-21 functions to promote cancer cell proliferation and movement. |
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• miR-21 suppresses the expression of hSulf-1 and PTEN in HCC cells. • Suppression of hSulf-1 or PTEN by miR-21 can activate AKT/ERK1/2 signaling. • Activation of AKT/ERK1/2 pathways induces EMT in HCC cells. • miR-21 functions to promote cancer cell proliferation and movement. |
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• miR-21 suppresses the expression of hSulf-1 and PTEN in HCC cells. • Suppression of hSulf-1 or PTEN by miR-21 can activate AKT/ERK1/2 signaling. • Activation of AKT/ERK1/2 pathways induces EMT in HCC cells. • miR-21 functions to promote cancer cell proliferation and movement. |
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MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways |
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