HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

Intrathecal delivery of histone deacetylase inhibitors ameliorates hypersensitivity in models of neuropathic pain. This effect may be mediated at the level of the spinal cord through inhibition of HDAC1 function.

Gespeichert in:
Autor*in:

Denk, Franziska [verfasserIn]

Huang, Wenlong

Sidders, Ben

Bithell, Angela

Crow, Megan

Grist, John

Sharma, Simone

Ziemek, Daniel

Rice, Andrew S.C.

Buckley, Noel J.

McMahon, Stephen B.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2013

Schlagwörter:

Histone deacetylase

Histone deacetylase inhibitors

Neuropathic pain

Umfang:

12

Übergeordnetes Werk:

Enthalten in: 336 MECHANISMS OF EGFR INHIBITORS - 2012, the journal of the International Association for the Study of Pain, New York, NY [u.a.]

Übergeordnetes Werk:

volume:154 ; year:2013 ; number:9 ; pages:1668-1679 ; extent:12

Links:

Volltext

DOI / URN:

10.1016/j.pain.2013.05.021

Katalog-ID:

ELV027247996

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