Parenteral nanosuspension of a novel synthesized antitumor candidate: Investigation of tissue biodistributions and plasma pharmacokinetics
Highlights • A novel synthesized p-terphenyl derivative (H2) has significant antitumor activity. • Precipitation and microfluidization method were combined to prepare nanosuspensions. • Compared with H2 solution, nanosuspension significantly changed drug biodistribution features.
Gespeichert in:
| Autor*in: |
Tian, Xiaona [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2013 |
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5 |
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| Übergeordnetes Werk: |
Enthalten in: Reaction mechanism investigation of furfural conversion to 2-methylfuran on Cu(1 1 1) surface - Ren, Guoqing ELSEVIER, 2018, an international journal devoted to the principles and applications of colloid and interface science, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:436 ; year:2013 ; day:5 ; month:09 ; pages:868-872 ; extent:5 |
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| DOI / URN: |
10.1016/j.colsurfa.2013.08.029 |
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| 520 | |a Highlights • A novel synthesized p-terphenyl derivative (H2) has significant antitumor activity. • Precipitation and microfluidization method were combined to prepare nanosuspensions. • Compared with H2 solution, nanosuspension significantly changed drug biodistribution features. | ||
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| 700 | 1 | |a Zhang, Dianrui |4 oth | |
| 700 | 1 | |a Shen, Jingyi |4 oth | |
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| 700 | 1 | |a Hao, Leilei |4 oth | |
| 700 | 1 | |a Shen, Yuemao |4 oth | |
| 700 | 1 | |a Zhang, Qiang |4 oth | |
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Parenteral nanosuspension of a novel synthesized antitumor candidate: Investigation of tissue biodistributions and plasma pharmacokinetics |
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Highlights • A novel synthesized p-terphenyl derivative (H2) has significant antitumor activity. • Precipitation and microfluidization method were combined to prepare nanosuspensions. • Compared with H2 solution, nanosuspension significantly changed drug biodistribution features. |
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Highlights • A novel synthesized p-terphenyl derivative (H2) has significant antitumor activity. • Precipitation and microfluidization method were combined to prepare nanosuspensions. • Compared with H2 solution, nanosuspension significantly changed drug biodistribution features. |
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Highlights • A novel synthesized p-terphenyl derivative (H2) has significant antitumor activity. • Precipitation and microfluidization method were combined to prepare nanosuspensions. • Compared with H2 solution, nanosuspension significantly changed drug biodistribution features. |
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Parenteral nanosuspension of a novel synthesized antitumor candidate: Investigation of tissue biodistributions and plasma pharmacokinetics |
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https://doi.org/10.1016/j.colsurfa.2013.08.029 |
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Li, Han Zhang, Dianrui Shen, Jingyi Jia, Lejiao Zheng, Dandan Liu, Guangpu Hao, Leilei Shen, Yuemao Zhang, Qiang |
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Li, Han Zhang, Dianrui Shen, Jingyi Jia, Lejiao Zheng, Dandan Liu, Guangpu Hao, Leilei Shen, Yuemao Zhang, Qiang |
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10.1016/j.colsurfa.2013.08.029 |
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2024-07-06T21:43:20.506Z |
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