Circulating tumor cells in breast cancer
Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Banys, Malgorzata [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2013transfer abstract |
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| Umfang: |
7 |
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| Übergeordnetes Werk: |
Enthalten in: Li-CO - Zhang, Peng-Fang ELSEVIER, 2022, international journal of clinical chemistry and applied molecular biology, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:423 ; year:2013 ; day:23 ; month:08 ; pages:39-45 ; extent:7 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.cca.2013.03.029 |
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| 520 | |a Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical outcome. Since bone marrow biopsy is an invasive procedure, evaluation of CTCs might become a desired alternative. Recent clinical trials have shown CTC detection to be a promising prognostic tool in both primary and metastatic setting. Evaluation of CTCs might be useful for therapy monitoring and their characterization might help to identify novel targets for biological therapies aimed at disrupting earliest steps of metastatic cascade. | ||
| 520 | |a Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical outcome. Since bone marrow biopsy is an invasive procedure, evaluation of CTCs might become a desired alternative. Recent clinical trials have shown CTC detection to be a promising prognostic tool in both primary and metastatic setting. Evaluation of CTCs might be useful for therapy monitoring and their characterization might help to identify novel targets for biological therapies aimed at disrupting earliest steps of metastatic cascade. | ||
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| 700 | 1 | |a Hagenbeck, Carsten |4 oth | |
| 700 | 1 | |a Hartkopf, Andreas |4 oth | |
| 700 | 1 | |a Fehm, Tanja |4 oth | |
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10.1016/j.cca.2013.03.029 doi GBVA2013020000001.pica (DE-627)ELV027543706 (ELSEVIER)S0009-8981(13)00129-0 DE-627 ger DE-627 rakwb eng 540 610 540 DE-600 610 DE-600 660 VZ 660 VZ 58.10 bkl Banys, Malgorzata verfasserin aut Circulating tumor cells in breast cancer 2013transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical outcome. Since bone marrow biopsy is an invasive procedure, evaluation of CTCs might become a desired alternative. Recent clinical trials have shown CTC detection to be a promising prognostic tool in both primary and metastatic setting. Evaluation of CTCs might be useful for therapy monitoring and their characterization might help to identify novel targets for biological therapies aimed at disrupting earliest steps of metastatic cascade. Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical outcome. Since bone marrow biopsy is an invasive procedure, evaluation of CTCs might become a desired alternative. Recent clinical trials have shown CTC detection to be a promising prognostic tool in both primary and metastatic setting. Evaluation of CTCs might be useful for therapy monitoring and their characterization might help to identify novel targets for biological therapies aimed at disrupting earliest steps of metastatic cascade. Müller, Volkmar oth Melcher, Carola oth Aktas, Bahriye oth Kasimir-Bauer, Sabine oth Hagenbeck, Carsten oth Hartkopf, Andreas oth Fehm, Tanja oth Enthalten in Elsevier Science Zhang, Peng-Fang ELSEVIER Li-CO 2022 international journal of clinical chemistry and applied molecular biology Amsterdam [u.a.] (DE-627)ELV008356149 volume:423 year:2013 day:23 month:08 pages:39-45 extent:7 https://doi.org/10.1016/j.cca.2013.03.029 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.10 Verfahrenstechnik: Allgemeines VZ AR 423 2013 23 0823 39-45 7 045F 540 |
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10.1016/j.cca.2013.03.029 doi GBVA2013020000001.pica (DE-627)ELV027543706 (ELSEVIER)S0009-8981(13)00129-0 DE-627 ger DE-627 rakwb eng 540 610 540 DE-600 610 DE-600 660 VZ 660 VZ 58.10 bkl Banys, Malgorzata verfasserin aut Circulating tumor cells in breast cancer 2013transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical outcome. Since bone marrow biopsy is an invasive procedure, evaluation of CTCs might become a desired alternative. Recent clinical trials have shown CTC detection to be a promising prognostic tool in both primary and metastatic setting. Evaluation of CTCs might be useful for therapy monitoring and their characterization might help to identify novel targets for biological therapies aimed at disrupting earliest steps of metastatic cascade. Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical outcome. Since bone marrow biopsy is an invasive procedure, evaluation of CTCs might become a desired alternative. Recent clinical trials have shown CTC detection to be a promising prognostic tool in both primary and metastatic setting. Evaluation of CTCs might be useful for therapy monitoring and their characterization might help to identify novel targets for biological therapies aimed at disrupting earliest steps of metastatic cascade. Müller, Volkmar oth Melcher, Carola oth Aktas, Bahriye oth Kasimir-Bauer, Sabine oth Hagenbeck, Carsten oth Hartkopf, Andreas oth Fehm, Tanja oth Enthalten in Elsevier Science Zhang, Peng-Fang ELSEVIER Li-CO 2022 international journal of clinical chemistry and applied molecular biology Amsterdam [u.a.] (DE-627)ELV008356149 volume:423 year:2013 day:23 month:08 pages:39-45 extent:7 https://doi.org/10.1016/j.cca.2013.03.029 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.10 Verfahrenstechnik: Allgemeines VZ AR 423 2013 23 0823 39-45 7 045F 540 |
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Banys, Malgorzata |
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10.1016/j.cca.2013.03.029 |
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| title_sort |
circulating tumor cells in breast cancer |
| title_auth |
Circulating tumor cells in breast cancer |
| abstract |
Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical outcome. Since bone marrow biopsy is an invasive procedure, evaluation of CTCs might become a desired alternative. Recent clinical trials have shown CTC detection to be a promising prognostic tool in both primary and metastatic setting. Evaluation of CTCs might be useful for therapy monitoring and their characterization might help to identify novel targets for biological therapies aimed at disrupting earliest steps of metastatic cascade. |
| abstractGer |
Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical outcome. Since bone marrow biopsy is an invasive procedure, evaluation of CTCs might become a desired alternative. Recent clinical trials have shown CTC detection to be a promising prognostic tool in both primary and metastatic setting. Evaluation of CTCs might be useful for therapy monitoring and their characterization might help to identify novel targets for biological therapies aimed at disrupting earliest steps of metastatic cascade. |
| abstract_unstemmed |
Detection of disseminated tumor cells (DTCs) in bone marrow and of circulating tumor cells (CTCs) in the blood has become a major focus of translational cancer research. DTC presence is a common phenomenon seen in 30–40% of primary breast cancer patients and is strongly associated with poor clinical outcome. Since bone marrow biopsy is an invasive procedure, evaluation of CTCs might become a desired alternative. Recent clinical trials have shown CTC detection to be a promising prognostic tool in both primary and metastatic setting. Evaluation of CTCs might be useful for therapy monitoring and their characterization might help to identify novel targets for biological therapies aimed at disrupting earliest steps of metastatic cascade. |
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| title_short |
Circulating tumor cells in breast cancer |
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Müller, Volkmar Melcher, Carola Aktas, Bahriye Kasimir-Bauer, Sabine Hagenbeck, Carsten Hartkopf, Andreas Fehm, Tanja |
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Müller, Volkmar Melcher, Carola Aktas, Bahriye Kasimir-Bauer, Sabine Hagenbeck, Carsten Hartkopf, Andreas Fehm, Tanja |
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2024-07-06T16:32:08.070Z |
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