Mixtures with relatives: A pedigree perspective
DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full genera...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Egeland, Thore [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014transfer abstract |
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| Schlagwörter: |
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| Umfang: |
6 |
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| Übergeordnetes Werk: |
Enthalten in: Modelling the impact of targeted interventions on the HCV epidemic in Pakistan: the road to HCV elimination - Lim, A.G. ELSEVIER, 2017, an international journal dedicated to the applications of genetics in the administration of justice, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:10 ; year:2014 ; pages:49-54 ; extent:6 |
| Links: |
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| DOI / URN: |
10.1016/j.fsigen.2014.01.007 |
|---|
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ELV028053893 |
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| 520 | |a DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. | ||
| 520 | |a DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. | ||
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10.1016/j.fsigen.2014.01.007 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001281.pica (DE-627)ELV028053893 (ELSEVIER)S1872-4973(14)00023-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.44 bkl Egeland, Thore verfasserin aut Mixtures with relatives: A pedigree perspective 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. Likelihoods Elsevier DNA mixtures Elsevier Forensics Elsevier Related contributors Elsevier Pedigrees Elsevier Dørum, Guro oth Vigeland, Magnus Dehli oth Sheehan, Nuala A. oth Enthalten in Elsevier Science Lim, A.G. ELSEVIER Modelling the impact of targeted interventions on the HCV epidemic in Pakistan: the road to HCV elimination 2017 an international journal dedicated to the applications of genetics in the administration of justice Amsterdam [u.a.] (DE-627)ELV014877864 volume:10 year:2014 pages:49-54 extent:6 https://doi.org/10.1016/j.fsigen.2014.01.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 44.44 Parasitologie Medizin VZ AR 10 2014 49-54 6 |
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10.1016/j.fsigen.2014.01.007 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001281.pica (DE-627)ELV028053893 (ELSEVIER)S1872-4973(14)00023-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.44 bkl Egeland, Thore verfasserin aut Mixtures with relatives: A pedigree perspective 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. Likelihoods Elsevier DNA mixtures Elsevier Forensics Elsevier Related contributors Elsevier Pedigrees Elsevier Dørum, Guro oth Vigeland, Magnus Dehli oth Sheehan, Nuala A. oth Enthalten in Elsevier Science Lim, A.G. ELSEVIER Modelling the impact of targeted interventions on the HCV epidemic in Pakistan: the road to HCV elimination 2017 an international journal dedicated to the applications of genetics in the administration of justice Amsterdam [u.a.] (DE-627)ELV014877864 volume:10 year:2014 pages:49-54 extent:6 https://doi.org/10.1016/j.fsigen.2014.01.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 44.44 Parasitologie Medizin VZ AR 10 2014 49-54 6 |
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10.1016/j.fsigen.2014.01.007 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001281.pica (DE-627)ELV028053893 (ELSEVIER)S1872-4973(14)00023-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.44 bkl Egeland, Thore verfasserin aut Mixtures with relatives: A pedigree perspective 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. Likelihoods Elsevier DNA mixtures Elsevier Forensics Elsevier Related contributors Elsevier Pedigrees Elsevier Dørum, Guro oth Vigeland, Magnus Dehli oth Sheehan, Nuala A. oth Enthalten in Elsevier Science Lim, A.G. ELSEVIER Modelling the impact of targeted interventions on the HCV epidemic in Pakistan: the road to HCV elimination 2017 an international journal dedicated to the applications of genetics in the administration of justice Amsterdam [u.a.] (DE-627)ELV014877864 volume:10 year:2014 pages:49-54 extent:6 https://doi.org/10.1016/j.fsigen.2014.01.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 44.44 Parasitologie Medizin VZ AR 10 2014 49-54 6 |
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10.1016/j.fsigen.2014.01.007 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001281.pica (DE-627)ELV028053893 (ELSEVIER)S1872-4973(14)00023-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.44 bkl Egeland, Thore verfasserin aut Mixtures with relatives: A pedigree perspective 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. Likelihoods Elsevier DNA mixtures Elsevier Forensics Elsevier Related contributors Elsevier Pedigrees Elsevier Dørum, Guro oth Vigeland, Magnus Dehli oth Sheehan, Nuala A. oth Enthalten in Elsevier Science Lim, A.G. ELSEVIER Modelling the impact of targeted interventions on the HCV epidemic in Pakistan: the road to HCV elimination 2017 an international journal dedicated to the applications of genetics in the administration of justice Amsterdam [u.a.] (DE-627)ELV014877864 volume:10 year:2014 pages:49-54 extent:6 https://doi.org/10.1016/j.fsigen.2014.01.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 44.44 Parasitologie Medizin VZ AR 10 2014 49-54 6 |
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10.1016/j.fsigen.2014.01.007 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001281.pica (DE-627)ELV028053893 (ELSEVIER)S1872-4973(14)00023-4 DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.44 bkl Egeland, Thore verfasserin aut Mixtures with relatives: A pedigree perspective 2014transfer abstract 6 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. Likelihoods Elsevier DNA mixtures Elsevier Forensics Elsevier Related contributors Elsevier Pedigrees Elsevier Dørum, Guro oth Vigeland, Magnus Dehli oth Sheehan, Nuala A. oth Enthalten in Elsevier Science Lim, A.G. ELSEVIER Modelling the impact of targeted interventions on the HCV epidemic in Pakistan: the road to HCV elimination 2017 an international journal dedicated to the applications of genetics in the administration of justice Amsterdam [u.a.] (DE-627)ELV014877864 volume:10 year:2014 pages:49-54 extent:6 https://doi.org/10.1016/j.fsigen.2014.01.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 44.44 Parasitologie Medizin VZ AR 10 2014 49-54 6 |
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DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. |
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DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. |
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DNA mixture evidence pertains to cases where several individuals may have contributed to a biological stain. Statistical methods and software for such problems are available and a large number of cases can be handled adequately. However, one class of mixture problems remains untreated in full generality in the literature, namely when the contributors may be related. Disregarding a plausible close relative of the perpetrator as an alternative contributor (identical twin is the most extreme case) may lead to overestimating the evidence against a suspect. Existing methods only accommodate pairwise relationships such as the case where the suspect and the victim are siblings, for example. In this paper we consider relationships in full generality, conveniently represented by pedigrees. In particular, these pedigrees may involve inbreeding, for instance when the parents of an individual of interest are first cousins. Furthermore our framework handles situations where the opposing parties in a court case (prosecution and defence) propose different family relationships. Consequently, our approach combines classical mixture and kinship problems. |
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