Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells
• Relative potencies (REPs) of dioxin-like compounds (DLCs) in lymphocytes (PBLs). • REPs for some DLCs varied by species (human vs. mouse) and congener. • REPs for PCB 126 in human PBLs significantly lower than WHO TEF. • In vitro-derived REPs similar to systemic REPs from in vivo experiments. • Hu...
Ausführliche Beschreibung
Autor*in: |
van Ede, Karin I. [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2014 |
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Schlagwörter: |
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Umfang: |
10 |
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Übergeordnetes Werk: |
Enthalten in: Toxicology letters - Chen, Yun-Ru ELSEVIER, 2019, an international journal for the rapid publication of short reports on all aspects of toxicology especially mechanisms of toxicity, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:226 ; year:2014 ; number:1 ; day:7 ; month:04 ; pages:43-52 ; extent:10 |
Links: |
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DOI / URN: |
10.1016/j.toxlet.2014.01.026 |
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Katalog-ID: |
ELV028160045 |
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10.1016/j.toxlet.2014.01.026 doi GBVA2014012000029.pica (DE-627)ELV028160045 (ELSEVIER)S0378-4274(14)00037-X DE-627 ger DE-627 rakwb eng 570 540 610 570 DE-600 540 DE-600 610 DE-600 610 VZ 42.13 bkl 44.33 bkl van Ede, Karin I. verfasserin aut Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells 2014 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Relative potencies (REPs) of dioxin-like compounds (DLCs) in lymphocytes (PBLs). • REPs for some DLCs varied by species (human vs. mouse) and congener. • REPs for PCB 126 in human PBLs significantly lower than WHO TEF. • In vitro-derived REPs similar to systemic REPs from in vivo experiments. • Human PBL-derived REPs contribute to improved human risk assessment for DLCs. 1234678-HpCDD Elsevier 123478-HxCDF Elsevier 1234678-HpCDF Elsevier TCDD Elsevier 12378-PeCDD Elsevier PCDF Elsevier PCDD Elsevier NDL Elsevier HepG2 Elsevier 123678-HxCDD Elsevier PCB 156 Elsevier CYP Elsevier PBL Elsevier 2378-TCDF Elsevier PCB 118 Elsevier EROD Elsevier PCB 77 Elsevier BMR Elsevier PCB 153 Elsevier 23478-PeCDF Elsevier 1234789-HpCDF Elsevier AhR Elsevier PCB Elsevier TEF Elsevier PAH Elsevier PCB 167 Elsevier PCB 189 Elsevier DLC Elsevier PCB 169 Elsevier PCB 74 Elsevier PCB 126 Elsevier REP Elsevier PCB 105 Elsevier 234678-HxCDF Elsevier Gaisch, Konrad P.J. oth van den Berg, Martin oth van Duursen, Majorie B.M. oth Enthalten in Elsevier Science Chen, Yun-Ru ELSEVIER Toxicology letters 2019 an international journal for the rapid publication of short reports on all aspects of toxicology especially mechanisms of toxicity Amsterdam [u.a.] (DE-627)ELV003574431 volume:226 year:2014 number:1 day:7 month:04 pages:43-52 extent:10 https://doi.org/10.1016/j.toxlet.2014.01.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 42.13 Molekularbiologie VZ 44.33 Physiologische Chemie VZ AR 226 2014 1 7 0407 43-52 10 045F 570 |
spelling |
10.1016/j.toxlet.2014.01.026 doi GBVA2014012000029.pica (DE-627)ELV028160045 (ELSEVIER)S0378-4274(14)00037-X DE-627 ger DE-627 rakwb eng 570 540 610 570 DE-600 540 DE-600 610 DE-600 610 VZ 42.13 bkl 44.33 bkl van Ede, Karin I. verfasserin aut Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells 2014 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Relative potencies (REPs) of dioxin-like compounds (DLCs) in lymphocytes (PBLs). • REPs for some DLCs varied by species (human vs. mouse) and congener. • REPs for PCB 126 in human PBLs significantly lower than WHO TEF. • In vitro-derived REPs similar to systemic REPs from in vivo experiments. • Human PBL-derived REPs contribute to improved human risk assessment for DLCs. 1234678-HpCDD Elsevier 123478-HxCDF Elsevier 1234678-HpCDF Elsevier TCDD Elsevier 12378-PeCDD Elsevier PCDF Elsevier PCDD Elsevier NDL Elsevier HepG2 Elsevier 123678-HxCDD Elsevier PCB 156 Elsevier CYP Elsevier PBL Elsevier 2378-TCDF Elsevier PCB 118 Elsevier EROD Elsevier PCB 77 Elsevier BMR Elsevier PCB 153 Elsevier 23478-PeCDF Elsevier 1234789-HpCDF Elsevier AhR Elsevier PCB Elsevier TEF Elsevier PAH Elsevier PCB 167 Elsevier PCB 189 Elsevier DLC Elsevier PCB 169 Elsevier PCB 74 Elsevier PCB 126 Elsevier REP Elsevier PCB 105 Elsevier 234678-HxCDF Elsevier Gaisch, Konrad P.J. oth van den Berg, Martin oth van Duursen, Majorie B.M. oth Enthalten in Elsevier Science Chen, Yun-Ru ELSEVIER Toxicology letters 2019 an international journal for the rapid publication of short reports on all aspects of toxicology especially mechanisms of toxicity Amsterdam [u.a.] (DE-627)ELV003574431 volume:226 year:2014 number:1 day:7 month:04 pages:43-52 extent:10 https://doi.org/10.1016/j.toxlet.2014.01.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 42.13 Molekularbiologie VZ 44.33 Physiologische Chemie VZ AR 226 2014 1 7 0407 43-52 10 045F 570 |
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10.1016/j.toxlet.2014.01.026 doi GBVA2014012000029.pica (DE-627)ELV028160045 (ELSEVIER)S0378-4274(14)00037-X DE-627 ger DE-627 rakwb eng 570 540 610 570 DE-600 540 DE-600 610 DE-600 610 VZ 42.13 bkl 44.33 bkl van Ede, Karin I. verfasserin aut Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells 2014 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Relative potencies (REPs) of dioxin-like compounds (DLCs) in lymphocytes (PBLs). • REPs for some DLCs varied by species (human vs. mouse) and congener. • REPs for PCB 126 in human PBLs significantly lower than WHO TEF. • In vitro-derived REPs similar to systemic REPs from in vivo experiments. • Human PBL-derived REPs contribute to improved human risk assessment for DLCs. 1234678-HpCDD Elsevier 123478-HxCDF Elsevier 1234678-HpCDF Elsevier TCDD Elsevier 12378-PeCDD Elsevier PCDF Elsevier PCDD Elsevier NDL Elsevier HepG2 Elsevier 123678-HxCDD Elsevier PCB 156 Elsevier CYP Elsevier PBL Elsevier 2378-TCDF Elsevier PCB 118 Elsevier EROD Elsevier PCB 77 Elsevier BMR Elsevier PCB 153 Elsevier 23478-PeCDF Elsevier 1234789-HpCDF Elsevier AhR Elsevier PCB Elsevier TEF Elsevier PAH Elsevier PCB 167 Elsevier PCB 189 Elsevier DLC Elsevier PCB 169 Elsevier PCB 74 Elsevier PCB 126 Elsevier REP Elsevier PCB 105 Elsevier 234678-HxCDF Elsevier Gaisch, Konrad P.J. oth van den Berg, Martin oth van Duursen, Majorie B.M. oth Enthalten in Elsevier Science Chen, Yun-Ru ELSEVIER Toxicology letters 2019 an international journal for the rapid publication of short reports on all aspects of toxicology especially mechanisms of toxicity Amsterdam [u.a.] (DE-627)ELV003574431 volume:226 year:2014 number:1 day:7 month:04 pages:43-52 extent:10 https://doi.org/10.1016/j.toxlet.2014.01.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 42.13 Molekularbiologie VZ 44.33 Physiologische Chemie VZ AR 226 2014 1 7 0407 43-52 10 045F 570 |
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10.1016/j.toxlet.2014.01.026 doi GBVA2014012000029.pica (DE-627)ELV028160045 (ELSEVIER)S0378-4274(14)00037-X DE-627 ger DE-627 rakwb eng 570 540 610 570 DE-600 540 DE-600 610 DE-600 610 VZ 42.13 bkl 44.33 bkl van Ede, Karin I. verfasserin aut Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells 2014 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Relative potencies (REPs) of dioxin-like compounds (DLCs) in lymphocytes (PBLs). • REPs for some DLCs varied by species (human vs. mouse) and congener. • REPs for PCB 126 in human PBLs significantly lower than WHO TEF. • In vitro-derived REPs similar to systemic REPs from in vivo experiments. • Human PBL-derived REPs contribute to improved human risk assessment for DLCs. 1234678-HpCDD Elsevier 123478-HxCDF Elsevier 1234678-HpCDF Elsevier TCDD Elsevier 12378-PeCDD Elsevier PCDF Elsevier PCDD Elsevier NDL Elsevier HepG2 Elsevier 123678-HxCDD Elsevier PCB 156 Elsevier CYP Elsevier PBL Elsevier 2378-TCDF Elsevier PCB 118 Elsevier EROD Elsevier PCB 77 Elsevier BMR Elsevier PCB 153 Elsevier 23478-PeCDF Elsevier 1234789-HpCDF Elsevier AhR Elsevier PCB Elsevier TEF Elsevier PAH Elsevier PCB 167 Elsevier PCB 189 Elsevier DLC Elsevier PCB 169 Elsevier PCB 74 Elsevier PCB 126 Elsevier REP Elsevier PCB 105 Elsevier 234678-HxCDF Elsevier Gaisch, Konrad P.J. oth van den Berg, Martin oth van Duursen, Majorie B.M. oth Enthalten in Elsevier Science Chen, Yun-Ru ELSEVIER Toxicology letters 2019 an international journal for the rapid publication of short reports on all aspects of toxicology especially mechanisms of toxicity Amsterdam [u.a.] (DE-627)ELV003574431 volume:226 year:2014 number:1 day:7 month:04 pages:43-52 extent:10 https://doi.org/10.1016/j.toxlet.2014.01.026 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 42.13 Molekularbiologie VZ 44.33 Physiologische Chemie VZ AR 226 2014 1 7 0407 43-52 10 045F 570 |
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differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells |
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Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells |
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• Relative potencies (REPs) of dioxin-like compounds (DLCs) in lymphocytes (PBLs). • REPs for some DLCs varied by species (human vs. mouse) and congener. • REPs for PCB 126 in human PBLs significantly lower than WHO TEF. • In vitro-derived REPs similar to systemic REPs from in vivo experiments. • Human PBL-derived REPs contribute to improved human risk assessment for DLCs. |
abstractGer |
• Relative potencies (REPs) of dioxin-like compounds (DLCs) in lymphocytes (PBLs). • REPs for some DLCs varied by species (human vs. mouse) and congener. • REPs for PCB 126 in human PBLs significantly lower than WHO TEF. • In vitro-derived REPs similar to systemic REPs from in vivo experiments. • Human PBL-derived REPs contribute to improved human risk assessment for DLCs. |
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• Relative potencies (REPs) of dioxin-like compounds (DLCs) in lymphocytes (PBLs). • REPs for some DLCs varied by species (human vs. mouse) and congener. • REPs for PCB 126 in human PBLs significantly lower than WHO TEF. • In vitro-derived REPs similar to systemic REPs from in vivo experiments. • Human PBL-derived REPs contribute to improved human risk assessment for DLCs. |
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