In vivo evaluation of 18F-labeled TCO for pre-targeted PET imaging in the brain
The tetrazine-trans-cylooctene cycloaddition using radiolabeled tetrazine or radiolabeled trans-cyclooctene (TCO) has been reported to be a very fast, selective and bioorthogonal reaction that could be useful for in vivo radiolabeling of molecules. We wanted to evaluate the in vivo biodistribution p...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
wyffels, Leonie [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2014 |
|---|
| Umfang: |
11 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Inflammatory Expression Profiles in Bladder Exstrophy Smooth Muscle: Normalization Over Time - Michaud, Jason E. ELSEVIER, 2023, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:41 ; year:2014 ; number:6 ; pages:513-523 ; extent:11 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.nucmedbio.2014.03.023 |
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10.1016/j.nucmedbio.2014.03.023 doi GBVA2014016000003.pica (DE-627)ELV028280253 (ELSEVIER)S0969-8051(14)00098-5 DE-627 ger DE-627 rakwb eng 610 570 610 DE-600 570 DE-600 610 VZ 44.88 bkl wyffels, Leonie verfasserin aut In vivo evaluation of 18F-labeled TCO for pre-targeted PET imaging in the brain 2014 11 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The tetrazine-trans-cylooctene cycloaddition using radiolabeled tetrazine or radiolabeled trans-cyclooctene (TCO) has been reported to be a very fast, selective and bioorthogonal reaction that could be useful for in vivo radiolabeling of molecules. We wanted to evaluate the in vivo biodistribution profile and brain uptake of 18F-labeled TCO ([18F]TCO) to assess its potential for pre-targeted imaging in the brain. Thomae, David oth Waldron, Ann-Marie oth Fissers, Jens oth Dedeurwaerdere, Stefanie oth Van der Veken, Pieter oth Joossens, Jurgen oth Stroobants, Sigrid oth Augustyns, Koen oth Staelens, Steven oth Enthalten in Elsevier Science Michaud, Jason E. ELSEVIER Inflammatory Expression Profiles in Bladder Exstrophy Smooth Muscle: Normalization Over Time 2023 Amsterdam [u.a.] (DE-627)ELV010596976 volume:41 year:2014 number:6 pages:513-523 extent:11 https://doi.org/10.1016/j.nucmedbio.2014.03.023 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.88 Urologie Nephrologie VZ AR 41 2014 6 513-523 11 045F 610 |
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In vivo evaluation of 18F-labeled TCO for pre-targeted PET imaging in the brain |
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The tetrazine-trans-cylooctene cycloaddition using radiolabeled tetrazine or radiolabeled trans-cyclooctene (TCO) has been reported to be a very fast, selective and bioorthogonal reaction that could be useful for in vivo radiolabeling of molecules. We wanted to evaluate the in vivo biodistribution profile and brain uptake of 18F-labeled TCO ([18F]TCO) to assess its potential for pre-targeted imaging in the brain. |
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The tetrazine-trans-cylooctene cycloaddition using radiolabeled tetrazine or radiolabeled trans-cyclooctene (TCO) has been reported to be a very fast, selective and bioorthogonal reaction that could be useful for in vivo radiolabeling of molecules. We wanted to evaluate the in vivo biodistribution profile and brain uptake of 18F-labeled TCO ([18F]TCO) to assess its potential for pre-targeted imaging in the brain. |
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The tetrazine-trans-cylooctene cycloaddition using radiolabeled tetrazine or radiolabeled trans-cyclooctene (TCO) has been reported to be a very fast, selective and bioorthogonal reaction that could be useful for in vivo radiolabeling of molecules. We wanted to evaluate the in vivo biodistribution profile and brain uptake of 18F-labeled TCO ([18F]TCO) to assess its potential for pre-targeted imaging in the brain. |
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10.1016/j.nucmedbio.2014.03.023 |
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